Itgb6 (NM_021359) Mouse Untagged Clone
CAT＃: MC221627
Itgb6 (untagged) - Mouse integrin beta 6 (Itgb6), transcript variant 2, (10ug)
CNY 10170.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2210409C20Rik; 4831415H04Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221627 representing NM_021359
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGATTGAGCTGGTCTGCCTGTTTCTGCTACTTCTAGGAAGGAATGATCACGTCCAAGGTGGCTGTG CCTGGGGTGGTGCAGAAAGCTGCTCAGACTGCCTGCTCACAGGACCCCACTGCGCCTGGTGCTCCCAGGA GAATTTCACCCACCTGTCTGGAGCTGGCGAGAGGTGCGACACCCCAGCGAATCTTTTAGCCAAAGGATGT CAACTACCCTTCATTGAAAACCCTGTCTCCCGCATAGAAGTCCTTCAAAATAAGCCTCTCAGCGTGGGCC GACAGAAGAACAGTTCTGACATTGTTCAGATTGCTCCTCAAAGCTTGGTTCTTAAATTGAGACCAGGGCG TGAGCAGACTCTGCAAGTGCAGGTCCGCCAAACTGAAGATTACCCAGTAGATCTGTATTACCTCATGGAC CTCTCCGCCTCTATGGATGACGACCTCAACACCATCAAAGAGCTTGGCTCCCGGCTGGCCAAAGAGATGT CCAAACTAACCAGCAACTTTAGACTGGGCTTTGGCTCTTTTGTGGAAAAGCCCGTTTCTCCTTTTATGAA AACAACCCCAGAGGAAATCACCAACCCTTGCAGTAGTATCCCCTATTTCTGCTTACCTACATTTGGATTC AAGCACATTTTGCCATTAACTGATGATGCCGAGAGATTCAATGAAATTGTGAGGAAACAGAAGATTTCTG CTAATATTGACACACCTGAAGGTGGATTTGATGCAATCATGCAGGCTGCTGTGTGTAAGGAAAAGATTGG CTGGCGCAATGACTCGCTCCACCTCCTGGTTTTTGTGAGTGATGCCGATTCTCATTTTGGAATGGACAGC AAGCTGGCAGGCATTGTCATTCCCAATGATGGACTCTGTCACTTGGACCACAGGAATGAATATTCCATGT CAACTGTCTTGGAATATCCAACTATCGGCCAACTCATTGATAAACTGGTACAAAACAACGTGCTACTGAT CTTTGCAGTCACCCAAGAACAAGTCCATCTGTATGAGAACTATGCAAAACTCATTCCTGGAGCAACCGTG GGACTGCTTCAGAAGGATTCTGGGAACATCCTTCAGCTGATCATCTCCGCTTATGAAGAACTGCGGTCTG AGGTGGAACTGGAAGTGTTAGGGGACACAGAAGGACTCAACCTGTCTTTCACAGCTCTCTGTAACAATGG TGTCCTCTTCCCACACCAAAAGAAATGCTCCCACATGAAAGTTGGAGACACAGCATCCTTCAATGTGACT GTGAGCGTATCCAACTGTGAGAAAAGAAGCAGGAACCTCATCATAAAGCCAGTGGGGCTGGGGGACACCC TAGAAATACTCGTCAGTGCAGAATGTGACTGCGACTGCCAGAGAGAAATAGAAACTAACAGCTCTAAGTG TCACAATGGGAATGGCTCCTTCCAGTGTGGGGTGTGTACCTGCAACCCCGGCCACATGGGTCCTCACTGC GAGTGTGGTGAGGATATGGTGAGCACGGATTCCTGCAAGGAGTCCCCGGGTCACCCTTCATGCAGTGGAA GGGGTGACTGCTATTGTGGGCAGTGCATCTGCCACTTATCGCCGTACGGAAGCATCTACGGACCTTACTG CCAGTGTGACAACTTCTCCTGTCTGAGACACAAAGGCCTTCTCTGTGGAGATAACGGTGACTGTGACTGT GGCGAGTGTGTGTGCCGGGATGGCTGGACAGGTGAATACTGTAACTGTACAACCAACAGGGACTCGTGTA CATCTGAGGATGGAGTGCTGTGCAGTGGACGTGGGGACTGTGTCTGTGGCAAGTGTGTCTGCAGAAACCC TGGAGCCTCAGGACCCACCTGTGAACGCTGTCCTACCTGTGGCGACCCCTGTAACTCTAAACGGAGTTGC ATCGAGTGCTACCTGTCTGCAGATGGCCAGGCCCAAGAAGAGTGTGCTGACAAGTGTAAAGCCATTGGTG CCACCATCAGTGAGGAAGATTTTTCAAAGGATACTTCTGTCTCCTGCTCTCTACAAGGAGAAAATGAATG CCTTATTACATTCCTAATAACTACGGATAATGAAGGGAAAACCATCATTCACAACATCAATGAAAAAGAC TGCCCCAAACCTCCAAACATTCCCATGATCATGTTGGGGGTGTCACTGGCGATCCTGCTCATCGGAGTTG TGCTACTGTGCATTTGGAAGCTGCTGGTATCATTTCATGACCGGAAGGAAGTTGCTAAATTTGAAGCAGA ACGCTCTAAGGCCAAGTGGCAAACGGGAACCAATCCTCTGTACCGAGGTTCCACCAGCACTTTTAAGAAC GTGACCTACAAGCACAGGGAGAAGCACAAAGCAGGCCTTTCCTCAGATGGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_021359 |
| Insert Size | 2364 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021359.3, NP_067334.1 |
| RefSeq Size | 4788 bp |
| RefSeq ORF | 2364 bp |
| Locus ID | 16420 |
| UniProt ID | Q9Z0T9 |
| Gene Summary | Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (PubMed:10025398). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:10025398).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210654 | Itgb6 (tGFP-tagged) - Mouse integrin beta 6 (Itgb6) |
CNY 10248.00 |
|
| MG227017 | Itgb6 (tGFP-tagged) - Mouse integrin beta 6 (Itgb6) transcript variant 2, (10ug) |
CNY 6370.00 |
|
| MR227017 | Itgb6 (Myc-DDK-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 2 |
CNY 5768.00 |
|
| MR227017L3 | Lenti ORF clone of Itgb6 (Myc-DDK-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 2 |
CNY 7700.00 |
|
| MR227017L4 | Lenti ORF clone of Itgb6 (mGFP-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 2 |
CNY 7700.00 |
