Plaa (NM_172695) Mouse Untagged Clone
CAT＃: MC221630
Plaa (untagged) - Mouse phospholipase A2, activating protein (Plaa), (10ug)
CNY 10170.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2410007N06; AI536418; AU018445; AW208417; D4Ertd618e; PLA2P; PLAP; Ufd3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221630 representing NM_172695
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGAGCGGCGCCTCCAGATACCGGCTGAGCTGCTCGCTCCCGGGCCACGAACTGGACGTGAGGGGCC TGGTGTGCTGCCTCTACCCGCCGGGAGCCTTTGTGTCTGTGTCCCGGGATCGGACCACCCGCCTCTGGGC TCCAGACAGTCCTAACAGGGGCTTTACAGAAATGCACTGTATGAGCGGCCACTCTAATTTTGTGTCTTGT GTGTGTATCATACCCTCAAGTGACATATATCCTCATGGACTGATTGCCACTGGAGGAAATGACCACAATA TTTGCATTTTCTCGCTGGACAGTCCAATGCCACTTTATATTTTAAAGGGTCACAAAGATACTGTTTGTAG TCTTTCTTCTGGAAAATTTGGGACATTACTTAGTGGCTCATGGGACACCACTGCTAAAGTCTGGCTGAAT GACAAATGCATGATGACATTACAGGGTCATACAGCCGCAGTATGGGCAGTAAAGATTTTACCTGAACAGG GCTTAATGCTAACTGGATCAGCAGACAAGACCATTAAACTATGGAAGGCTGGAAGATGTGAGAGGACTTT TTTAGGGCATGAAGACTGTGTAAGAGGCTTGGCAATCTTGAGTGAGACAGAATTTCTTTCCTGTGCAAAC GATGCTAGTATTAGAAGGTGGCAGATCACTGGCGAGTGTCTGGAAGTATACTTTGGACATACAAATTATA TTTATAGCATATCTGTCTTTCCAAACTCCAAAGATTTTGTGACCACTGCAGAAGACAGATCTCTAAGAAT ATGGAAACATGGTGAATGCGCCCAAACAATCCGACTTCCAGCTCAGTCTATATGGTGTTGCTGCGTACTG GAAAATGGTGACATTGTGGTTGGTGCGAGTGATGGTATTATTAGGGTGTTTACAGAGTCAGAGGAGCGGA CAGCAAGTGCTGAGGAAATCAAAGCTTTTGAGAGAGAGCTCTCTCAGGCAACTATCGATTCCAAAACTGG TGACTTGGGGGATATTAATGCGGAGCAGCTTCCTGGGAGGGAACATCTCAGTGAGCCAGGTACTAGAGAA GGACAGACTCGTCTAATCAGAGATGGAGAGAGAGTTGAAGCCTATCAGTGGAGTGTTAGTGACGGGAGGT GGATAAAAATTGGTGATGTTGTTGGCTCATCTGGTGCTAATCAGCAAACATCTGGAAAAGTTTTATATGA AGGGAAAGAATTTGATTATGTTTTCTCAATCGATGTGAATGAAGGTGGACCATCGTATAAATTACCATAT AATGTCAGTGACGATCCCTGGCTAGTTGCATACAACTTCTTGCAGAAAAATGATTTGAATCCCATGTTTC TGGATCAGGTGGCTAAATTTATTATTGATAACACAAAAGGTCAAACACTGGGACTTGGGAATACCAGTTT TTCAGATCCGTTTACAGGTGGTGGTCGCTATGTTCCAGGAACTTCAGGACCTTCCAACACAGTGCAGACA GCAGATCCTTTCACAGGTGCTGGGCGTTACATGCCAGGTTCTGCAGGTATGGACACCACCATGACTGGAG TTGATCCATTTACAGGGAACAGTGCCTACCGATCAGCTGCATCTAAAACAGTGAACATTTATTTCCCCAA AAAAGAAGCTCTTACCTTTGACCAAGCAAACCCTACACAAATATTAGGAAAACTGAAGGAACTTAATGGA ACTGCACCTGAAGAGAAGAAGCTAACTGAAGACGACTTAGTACTTCTTGAAAAGATACTGTCCCTGATTT GTAATAATTCCTCAGAAAAGCCAACGGCCCAGCAACTTCAGATTTTGTGGAAAGCTATCAACTGGCCTGA AGACATTGTCTTTCCTGCACTTGACATTCTTCGCCTATCGATTAAGCATCCCAATGTGAATGAGAATTTC TGCAATGAAAAAGGAGACCAGTTCAGCAGCCATCTTATCAACCTTCTGAACCCCAAAGGAAAGCCAGCAA ACCAGCTGCTTGCTCTTAGGACTTTTTGCAATTGCTTTGTTAGTCAGGCAGGACAAAAGCTCATGATGTC CCAGAGGGAGTCACTGATGTCACATGCAATAGAACTGAAATCCGGGAGTAATAAGAACATTCATATTGCT CTGGCTACATTGACCTTGAACTATTCTGTTTGTTTCCATAAAGACCATAACATTGAAGGGAAAGCTCAAT GCCTCTCAGTAATTAGCACAATCTTGGAAGTTGTGCAAGACCTAGAAGCCACGTTTAGACTCCTTGTGGC TCTTGGGACACTTATCAGTGATGATTCAAATGCTATACAATTAGCCAAATCTTTAGGTGTTGATTCTCAA ATAAAAAAGTATGTCTCCGTATCAGAGCCAGCTAAAGTGAGTGAATGCTGTAGACTTGTCTTACATTTGC TGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_172695 |
| Insert Size | 2385 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_172695.2, NP_766283.2 |
| RefSeq Size | 6815 bp |
| RefSeq ORF | 2385 bp |
| Locus ID | 18786 |
| UniProt ID | P27612 |
| Gene Summary | Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (By similarity). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (PubMed:28413018). May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (By similarity). Plays a role in cerebellar Purkinje cell development (PubMed:28413018). Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:28007986).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG221020 | Plaa (tGFP-tagged) - Mouse phospholipase A2 activating protein (Plaa), (10ug) |
CNY 6370.00 |
|
| MR221020 | Plaa (Myc-DDK-tagged) - Mouse phospholipase A2, activating protein (Plaa) |
CNY 5824.00 |
|
| MR221020L3 | Lenti ORF clone of Plaa (Myc-DDK-tagged) - Mouse phospholipase A2, activating protein (Plaa) |
CNY 7700.00 |
|
| MR221020L4 | Lenti ORF clone of Plaa (mGFP-tagged) - Mouse phospholipase A2, activating protein (Plaa) |
CNY 7700.00 |
