Usp37 (NM_176972) Mouse Untagged Clone
CAT＃: MC222978
Usp37 (untagged) - Mouse ubiquitin specific peptidase 37 (Usp37), (10ug)
CNY 12640.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 4932415L06Rik; C330008N13Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222978 representing NM_176972
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCTCCCCTGAAGATCTATGGTCCTATCAGAATTCGAAGCATGCAGACTGGGATTACAAAGTGGAAAG AAGGGTCCTTTGAAATTGTGGAAAAAGACAATAGAGTCAGCCTGCTCGTTCACTACAACACTGGAGGAAT TCCAAGAGTGTTTCAGCTAAGTCATAACATTAAAAATGTGGTACTACGACCCAGTGGAATAAAACAAAGC CGCCTAATGTTGACTTTACAAGATAACAGCTTCTTGTCTATTGACAAAGTACCAAGTAAGGATGCAGAGG AAATGAGGTTGTTCCTAGATGCCGTCCATCAAAACAGACTTCATGCAGCTATGAAAGCTTCTCAAGGTTC TGGTAGTTTTGGAACTATTCTGGGCAGCAGGACCTCTCAGAAGGAAACTAACAGACAGCTTTCTTACTCA GACAATCAGGCCTCTTCAAAAAGAGGAAGTTTAGAAACTAAAGATGAAATTCCATTTCGAAAAGTTCTTG GCAGTCCTGGTAGAGGACCAATTAAGACTGTAACTGGAGGTGGAATGGCTGTTACCCGGACTATTCCTTC TTTGACGCTGACATCAACACCTCTTAGATCAGGATTATTAGAAAACCGCACTGAAAAGAGGAAAAGAATG TTATCTGGTTCAGAGCTGACTGAAGATTACCCTAAGGAAAATGACTCATCATCGAACAACAAAGCTATGA CAGACCCTTCAAGAAAATATTTAACCAGCTGTAGAGAAAAGCAGCTGAGTTTGAAACAGGCAGAAGAAAA TCGAACATCAGGGCTTTTACCTCTGCAGTCATCCTCATTCTATGGGAGCAGAGCTGGATCAAAGGACTAC TCTTCTGGTGTCACTAACCTGGACAGGTGTAATGTTTCAAGCCAGACTCCTTCTGCCAAAAGAAGCCTGG GGTTTCTTCCTCAGCCAACTCCTCTGTCTGTTAAAAAACTGAGGTGTAACCAGGATTACGCGGGCTGGAA CAGACCTAGAGTGCCCCTTTCCTCCCATCAACAGCAGCTGCAGGGATTCTCCAACTTGGGAAATACATGC TATATGAATGCTATCTTACAATCTCTGTTTTCACTCCAGTCATTTGCAAATGATTTGCTTAAACAAAGTA TCCCATGGAAGAAAATTCCATTCAATGCACTTATCAGACGCTTTGCAAACCTGCTTATTAAAAAAGATAT TTGTAATTCAGAGACCAAAAAAGAACTACTTAAGAAGGTTAAAAATGCTATTTCAGCTACTGCAGAGAGA TTCTCTGGCTATGTCCAAAATGATGCTCATGAATTTTTAAGTCAGTGCTTAGATCAGCTAAAGGAGGATA TGGAAAAACTGAATAAAACTTGGAAGACAGAACCTGTCCTTGGAGAAGAAAATTTGCCAGATACATCAGC TACCAAAGTGTTCACGTGCCCTGTTATTACAAACTTGGAGTTTGAAGTTCAGCACTCCATTATCTGTAAA GCATGTGGAGAAACTATTCCCAAAAGAGAACAGTTCAATGACCTCTCCATTGACCTTCCTCGGAGGAAAA AGCCACTCCCTCCTCGTTCAATCCAAGATTCTCTCGATCTTTTCTTTAGGGCAGAAGAACTTGAATACTC ATGTGAAAAGTGTGGTGGAAAATGTGCTCTTGTCAGGCACAAATTTAACAGGCTGCCCAGGGTCCTCATC CTTCATTTGAAGCGATACAGCTTCAATGTGGCTCTCTCACTTAACAACAAGCTCGGACAGCAAGTCATCA TCCCAAGATTCCTGACCCTGGCCTCCCACTGCACTGAGAGCACAAAGCCGCCGGTCACCCTTGGGTGGAG CGCACCCGTGGCAATTTCTAGACCATTGAGAGCCTGTCAAATGGTGAATTCCTGCATCACCAGCCCTTCT GCACCTTCAAAGAAATTCACCTTCAAATCCAAGAGCTCCGTGACATCATGCCTTGATTCAGACAGTGAGG ATGAACTTAAACGCTCTGTGGTCCTCAGTCAGAGACTTTGTGATTTGCCAGGCAATGAACAGTACCAGGA AGATGTGGAAAAAGATTTGAAATTGTGCAGATTAGAGCCTGGGAAGGCAGAACTGGAGAACTCAGGATTT GACAGAATGAGTGAGGAAGAGGTGCTGGCAGCTGTGTTAGAGATAAGCAGGAGAGAAGCTTCGCCGGTAC TTAGCCCTGAAGATGATGATAAGCCAACCAGCAGTCCGGACACCGGCTTTGCAGAAGATGATATTCCAGA AATGCCTGAAAATCCAGATGCTATGGAAATTGAGAAGTCCAAAACAATCACTGAGCCAGGTCCTGCTAGT TTTACTGAGATAACAAAAGACTGTGATGAGAATAAAGAAAACAAAACTCCAGAAGGCTCTCAGGGAGAGG TTGATTGGCTCCAGCAGTATGACGTAGACCGGGAAAGAGAAGAGCAGGAGCTGCAGCAAGCACTGGCTCA GAGCCTTCAAGAGCAAGAGGCTTGGGAACAGAAGGAAGATGACGACCTCAAAAGGGCTACAGAATTAAGT CTTCAAGAGTTTAACAACTCTTTTCTGGATTCCCTGGGCTCAGATGAGGACTCTGGAAATGAGGATGTTT TTGATATGGAGTACACAGAAGCTGAAGCTGAGGAGCTGAAAAGAAATGCTGAGACAGGAGCTCTTCCTCA TTCCTATCGGCTCATCAGTGTTGTCAGTCACATTGGGAGCACTTCTTCCTCAGGTCATTACATTAGTGAT GTGTATGACATTAAGAAACAGGCATGGTTCACTTACAATGACCTGGAGGTCTCTAAAATCCAAGAGGCTG CCGTGCAGAGTGATCGAGATCGCAGCGGCTATATCTTCTTCTATATGCACAAGGAGATCTTTGATGAGTT GCTGGAGACAGAAAAAACCTCTCAGGCGCTTAGCATGGAGGTGGGGAGAGCTGCCCGTCAGGCTTCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_176972 |
| Insert Size | 2940 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_176972.4, NP_795946.2 |
| RefSeq Size | 7196 bp |
| RefSeq ORF | 2940 bp |
| Locus ID | 319651 |
| UniProt ID | Q8C0R0 |
| Gene Summary | Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226485 | Usp37 (tGFP-tagged) - Mouse ubiquitin specific peptidase 37 (Usp37), (10ug) |
CNY 7890.00 |
|
| MR226485 | Usp37 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 37 (Usp37) |
CNY 7176.00 |
|
| MR226485L3 | Lenti ORF clone of Usp37 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 37 (Usp37) |
CNY 9030.00 |
|
| MR226485L4 | Lenti ORF clone of Usp37 (mGFP-tagged) - Mouse ubiquitin specific peptidase 37 (Usp37) |
CNY 9030.00 |
