Casr (NM_013803) Mouse Untagged Clone
CAT＃: MC223475
Casr (untagged) - Mouse calcium-sensing receptor (Casr), (10ug)
CNY 11280.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | CaR; Gprc2a |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223475 representing NM_013803
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCATGGTTTGGCTACTGTTTGGCCCTCCTGGCTCTCACCTGGCACTCCTCTGCCTATGGGCCTGACC AGCGAGCCCAAAAGAAGGGGGACATTATCCTAGGAGGTCTCTTTCCTATCCATTTTGGAGTAGCAGCCAA AGATCAAGATCTGAAGTCAAGACCAGAGTCTGTGGAGTGCATCAGGTATAACTTCCGTGGATTCCGATGG TTACAAGCCATGATCTTTGCCATAGAGGAGATAAACAGCAGCCCCGCCCTTCTTCCCAACATGACTCTGG GATATAGGATATTCGACACCTGTAACACCGTCTCCAAGGCTCTGGAGGCCACCTTGAGTTTTGTTGCCCA GAACAAAATCGATTCTCTGAACCTGGATGAGTTCTGCAACTGCTCCGAGCACATCCCTTCAACCATCGCA GTGGTGGGAGCAACCGGCTCCGGTGTCTCCACAGCGGTAGCCAACCTGCTGGGACTTTTCTATATCCCCC AGGTGAGCTACGCCTCCTCTAGCAGGCTTCTCAGCAATAAGAACCAGTTCAAGTCCTTCCTCCGCACCAT TCCCAACGACGAACACCAGGCCACCGCGATGGCTGACATTATCGAGTATTTCCGTTGGAACTGGGTGGGC ACAATTGCAGCCGACGACGACTATGGCAGGCCTGGCATTGAGAAGTTCCGAGAGGAAGCCGAGGAGAGGG ACATCTGCATTGACTTCAGCGAGCTCATCTCCCAGTACTCTGATGAGGAAGAGATCCAGCAGGTGGTGGA AGTGATCCAGAACTCTACAGCCAAGGTCATTGTCGTTTTCTCCAGCGGCCCAGACCTAGAACCTCTCATC AAGGAGATTGTGCGCCGTAACATCACAGGCAGGATCTGGCTGGCCAGCGAGGCCTGGGCCAGTTCCTCCC TGATTGCTATGCCTGAGTACTTCCATGTAGTCGGGGGTACCATTGGGTTCGGTCTGAAGGCTGGGCAGAT TCCAGGCTTCCGAGAATTCCTACAGAAAGTCCATCCCAGGAAGTCTGTCCACAATGGTTTTGCCAAAGAG TTTTGGGAAGAAACATTTAATTGCCACCTGCAAGACGGCGCAAAAGGACCTTTACCCGTGGACACCTTCG TGAGAAGTCACGAGGAAGGCGGCAACAGGTTACTCAATAGCTCCACTGCCTTCCGACCCCTCTGCACGGG GGATGAAAACATCAATAGTGTCGAGACCCCTTACATGGACTACGAACATTTACGGATATCCTACAACGTG TACTTAGCCGTCTACTCCATTGCGCACGCCCTGCAAGATATATACACCTGCTTACCCGGAAGAGGGCTTT TCACCAACGGGTCCTGTGCAGACATCAAGAAGGTTGAGGCCTGGCAGGTCCTGAAACACCTACGGCACCT GAATTTCACCAACAACATGGGGGAGCAGGTGACCTTCGATGAGTGCGGTGACCTGGTGGGGAACTACTCC ATCATCAACTGGCACCTCTCCCCAGAGGACGGCTCCATTGTGTTCAAGGAAGTTGGGTACTACAATGTGT ATGCCAAGAAGGGAGAAAGACTGTTCATCAATGAGGGGAAGATCTTGTGGAGTGGGTTCTCCAGAGAGGT GCCCTTCTCCAACTGCAGCCGGGACTGTCAGGCAGGGACCAGGAAGGGCATCATTGAGGGAGAGCCCACC TGCTGTTTTGAGTGTGTGGAGTGTCCTGACGGCGAGTACAGTGGTGAGACAGATGCGAGTGCCTGTGACA AGTGCCCGGATGACTTCTGGTCCAATGAGAACCACACTTCCTGCATTGCCAAGGAGATTGAGTTCCTGGC GTGGACTGAGCCCTTTGGAATCGCTCTCACTCTCTTTGCGGTGCTGGGCATTTTCCTGACCGCCTTTGTG CTGGGCGTCTTCATCAAGTTCCGAAACACGCCCATTGTCAAGGCCACCAACCGAGAGCTGTCCTACCTCC TGCTCTTCTCACTCCTCTGCTGCTTCTCCAGCTCCCTGTTCTTCATTGGGGAGCCCCAGGACTGGACCTG CCGCCTGCGACAGCCCGCCTTCGGCATCAGCTTCGTGCTTTGTATCTCGTGCATCTTGGTGAAGACCAAT CGAGTCCTCCTGGTATTTGAGGCCAAAATACCCACCAGCTTCCACCGGAAGTGGTGGGGACTCAACCTGC AGTTCCTGCTGGTTTTCCTCTGCACCTTCATGCAGATTGTCATCTGCATCATCTGGCTCTACACGGCACC CCCCTCCAGCTACCGCAACCACGAGCTGGAAGACGAAATCATCTTCATCACGTGCCATGAGGGCTCACTC ATGGCGCTCGGCTCCCTGATCGGCTACACCTGCCTCCTGGCTGCCATCTGCTTCTTCTTTGCCTTCAAGT CTCGGAAGCTGCCAGAGAACTTCAACGAAGCCAAGTTCATTACCTTCAGCATGCTCATCTTCTTCATCGT CTGGATCTCCTTCATTCCAGCCTATGCCAGCACCTACGGCAAGTTTGTCTCTGCCGTGGAGGTGATCGCC ATCCTGGCAGCCAGCTTTGGCTTGCTAGCCTGCATCTTCTTCAACAAGGTCTACATCATCCTCTTCAAGC CTTCACGGAACACCATCGAGGAGGTGCGCTCCAGCACTGCGGCTCATGCTTTCAAAGTGGCAGCCCGCGC CACTCTACGCCGCCCCAACATCTCCCGGAAGCGGTCCAGCAGCCTCGGAGGCTCCACTGGGTCGATTCCC TCCTCCTCCATCAGCAGCAAAAGCAACAGCGAAGACCGGTTCCCACAGCCGGAGAGGCAGAAGCAACAGC AACCACTGGCCCTGACCCAGCAAGAACAGCAGCAGCAGCCCCTGACTCTCCAGCCGCAGCAACAGCAACA GCCACAGCAGCCGAGATGCAAACAGAAGGTCATCTTCGGCAGTGGCACAGTCACCTTCTCTCTGAGCTTT GATGAGCCTCAGAAGAATGCTATGGCCCACAGGAACTCCATGCGCCAGAACTCCCTGGAGGCCCAGAAGA GCAATGACACTTTGAACAGACACCAGGCCCTGCTTCCCCTACAGTGTGCAGAGGCGGACTCAGAAATGAC CATTCAGGAGACGGGCTTGCAAGGGCCAATGGTGGGGGACCACCAGCCAGAAATAGAAAGCCCAGATGAA ATGTCCCCAGCTCTGGTCATGTCCACCTCTCGGAGCTTCGTCATCAGCGGTGGAGGTAGCTCTGTGACGG AAAACATACTGCACTCCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_013803 |
| Insert Size | 3240 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_013803.2, NP_038831.2 |
| RefSeq Size | 4549 bp |
| RefSeq ORF | 3240 bp |
| Locus ID | 12374 |
| UniProt ID | Q9QY96 |
| Gene Summary | G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (By similarity). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (PubMed:7493018). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as Trp or Phe, act concertedly with divalent cations, such as calcium or magnesium, to achieve full receptor activation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223303 | Casr (tGFP-tagged) - Mouse calcium-sensing receptor (Casr), (10ug) |
CNY 12872.00 |
|
| MR223303 | Casr (Myc-DDK-tagged) - Mouse calcium-sensing receptor (Casr) |
CNY 11272.00 |
|
| MR223303L1 | Lenti ORF clone of Casr (Myc-DDK-tagged) - Mouse calcium-sensing receptor (Casr) |
CNY 12640.00 |
|
| MR223303L2 | Lenti ORF clone of Casr (mGFP-tagged) - Mouse calcium-sensing receptor (Casr) |
CNY 13672.00 |
|
| MR223303L3 | Lenti ORF clone of Casr (Myc-DDK-tagged) - Mouse calcium-sensing receptor (Casr) |
CNY 13672.00 |
|
| MR223303L4 | Lenti ORF clone of Casr (mGFP-tagged) - Mouse calcium-sensing receptor (Casr) |
CNY 12640.00 |
