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Slurp1 (NM_020519) Mouse Tagged ORF Clone
CAT＃: MR226243
- TrueORF®
Slurp1 (Myc-DDK-tagged) - Mouse secreted Ly6/Plaur domain containing 1 (Slurp1)
ORF Plasmid: tGFP
"NM_020519" in other vectors (4)
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CNY 1,200.00
CNY 3,705.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 1110021N19Rik; AI415082; ARS; ArsB; Slurp-1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR226243 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCCTTCGCTGGGCCATGTGGCTGCTGCTCTTGGCAGCCTGGAGCATGGGCTATGGTGAGGCCTTCC GATGCTATACCTGTGAGCAGCCCACGGCCATTAACTCATGCAAGAATATTGCTCAGTGCAAGATGGAAGA CACAGCCTGTAAGACTGTACTGGAGACAGTGGAAGCAGCGTTCCCCTTCAACCACAGTCCCATGGTGACC CGCTCCTGCTCCAGCTCGTGTCTGGCCACCGACCCTGATGGCATTGGCGTTGCCCATCCTGTCTTCTGTT GCTTCCGTGACCTCTGCAACTCAGGGTTTCCAGGCTTCGTGGCAGGCCTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR226243 protein sequence
Red=Cloning site Green=Tags(s) MTLRWAMWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIAQCKMEDTACKTVLETVEAAFPFNHSPMVT RSCSSSCLATDPDGIGVAHPVFCCFRDLCNSGFPGFVAGL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_020519 |
| ORF Size | 333 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_020519.2 |
| RefSeq Size | 525 bp |
| RefSeq ORF | 333 bp |
| Locus ID | 57277 |
| UniProt ID | Q9Z0K7 |
| MW | 12 kDa |
| Gene Summary | Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner (By similarity). In T cells may be involved in regulation of intracellular Ca(2+) signaling (PubMed:17286989). Seems to have a immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation (PubMed:23139280, PubMed:25168896).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC210135 | Slurp1 (untagged) - Mouse secreted Ly6/Plaur domain containing 1 (Slurp1), (10ug) |
CNY 3,990.00 |
|
| MG226243 | Slurp1 (tGFP-tagged) - Mouse secreted Ly6/Plaur domain containing 1 (Slurp1), (10ug) |
CNY 2,850.00 |
|
| MR226243L3 | Lenti ORF clone of Slurp1 (Myc-DDK-tagged) - Mouse secreted Ly6/Plaur domain containing 1 (Slurp1) |
CNY 4,750.00 |
|
| MR226243L4 | Lenti ORF clone of Slurp1 (mGFP-tagged) - Mouse secreted Ly6/Plaur domain containing 1 (Slurp1) |
CNY 4,750.00 |
