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Dlg4 (NM_007864) Mouse Tagged ORF Clone
CAT＃: MR227405
- TrueORF®
Dlg4 (Myc-DDK-tagged) - Mouse discs, large homolog 4 (Drosophila) (Dlg4), transcript variant 1
ORF Plasmid: tGFP
"NM_007864" in other vectors (4)
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CNY 7,220.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | Dlgh4; PSD-95; PSD95; SAP90; SAP90A |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR227405 representing NM_007864
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACTGTCTCTGTATAGTGACAACCAAGAAATACCGCTACCAAGATGAAGACACGCCCCCTCTGGAAC ACAGCCCGGCCCACCTCCCCAACCAGGCCAATTCTCCCCCTGTGATTGTCAACACGGACACCCTAGAAGC CCCAGGATATGAGTTGCAGGTGAACGGAACAGAGGGGGAGATGGAGTATGAGGAGATCACATTGGAAAGG GGTAACTCAGGTCTGGGCTTCAGCATCGCAGGTGGCACCGACAACCCACACATCGGTGACGACCCATCCA TCTTTATCACCAAGATCATTCCTGGTGGGGCTGCAGCCCAGGATGGCCGCCTCAGGGTCAACGACAGCAT CCTGTTTGTCAATGAAGTGGATGTCCGGGAGGTGACCCATTCAGCTGCAGTGGAGGCCCTCAAAGAGGCG GGTTCCATCGTTCGCCTCTACGTCATGCGCCGGAAACCCCCAGCTGAGAAGATCATAGAGATCAAGCTTA TCAAAGGGCCTAAAGGACTTGGCTTCAGCATCGCAGGGGGCGTTGGGAACCAGCACATCCCTGGAGATAA TAGCATCTACGTAACCAAGATCATCGAAGGAGGCGCTGCCCACAAGGATGGCAGGTTGCAGATCGGAGAC AAGATCCTGGCGGTCAACAGTGTGGGGCTAGAGGATGTCATGCATGAGGACGCCGTGGCAGCCCTGAAGA ACACATATGACGTTGTGTACCTAAAGGTGGCCAAGCCCAGCAATGCCTACCTGAGTGACAGCTATGCTCC CCCAGACATCACAACCTCATATTCTCAGCACCTGGACAATGAGATCAGTCATAGCAGCTACTTGGGCACC GACTACCCCACAGCCATGACCCCCACTTCCCCTCGGCGCTACTCCCCCGTGGCCAAGGACCTGCTAGGGG AGGAAGATATTCCCCGGGAACCAAGGCGGATCGTGATCCATCGGGGCTCCACCGGCCTGGGCTTCAACAT TGTGGGCGGCGAGGACGGTGAAGGCATCTTCATCTCCTTCATCCTTGCTGGGGGTCCAGCTGACCTCAGT GGGGAGCTACGGAAGGGGGACCAGATCCTGTCGGTCAATGGTGTTGACCTCCGCAATGCCAGTCATGAAC AGGCTGCCATTGCCCTGAAGAACGCGGGTCAGACGGTCACGATCATCGCTCAGTATAAACCAGAAGAGTA TAGCCGATTCGAGGCCAAGATCCATGATCTTCGGGAACAGCTTATGAATAGTAGCCTGGGCTCAGGGACT GCATCTCTGCGAAGCAACCCCAAGCGGGGCTTCTATATCAGGGCCCTGTTTGACTACGACAAGACCAAGG ACTGCGGTTTCTTGAGCCAGGCCCTGAGCTTCCACTTTGGGGATGTGCTTCATGTAATTGACGCCAGCGA CGAAGAGTGGTGGCAAGCGCGGCGGGTCCACTCTGACAGTGAGACCGATGACATTGGCTTCATTCCCAGC AAACGGCGGGTCGAGCGACGAGAGTGGTCAAGGTTAAAGGCCAAGGACTGGGGCTCCAGCTCTGGATCAC AGGGTCGAGAAGACTCGGTTCTGAGCTATGAGACGGTGACGCAGATGGAAGTGCACTACGCTCGCCCCAT CATCATCCTTGGGCCTACCAAAGACCGTGCCAACGATGATCTTCTCTCCGAGTTCCCCGACAAGTTTGGA TCCTGTGTCCCTCATACGACACGTCCTAAGCGGGAATATGAGATAGACGGCCGCGATTACCACTTTGTCT CCTCCCGGGAGAAAATGGAGAAGGACATTCAGGCGCACAAGTTCATTGAGGCTGGCCAGTACAACAGCCA CCTCTACGGGACCAGCGTCCAGTCTGTGCGAGAGGTAGCAGAGCAGGGGAAGCACTGCATCCTTGATGTC TCAGCCAATGCCGTGCGGCGGCTGCAGGCGGCCCACCTGCACCCTATCGCCATCTTCATCCGTCCCCGCT CCCTGGAGAATGTGCTAGAGATCAATAAGCGGATCACAGAGGAGCAAGCCCGGAAAGCCTTCGACAGGGC CACGAAGCTGGAGCAGGAGTTCACGGAGTGCTTCTCAGCCATCGTAGAGGGCGACAGCTTTGAAGAGATC TATCACAAAGTGAAACGTGTCATCGAAGACCTCTCAGGCCCCTACATCTGGGTCCCAGCCCGAGAGAGAC TC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR227405 representing NM_007864
Red=Cloning site Green=Tags(s) MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLER GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEA GSIVRLYVMRRKPPAEKIIEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGD KILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGT DYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLS GELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFHFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPS KRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFG SCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDV SANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEI YHKVKRVIEDLSGPYIWVPARERL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_007864 |
| ORF Size | 2172 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007864.3, NP_031890.1 |
| RefSeq Size | 3339 bp |
| RefSeq ORF | 2175 bp |
| Locus ID | 13385 |
| UniProt ID | Q62108 |
| MW | 80.9 kDa |
| Gene Summary | Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC221074 | Dlg4 (untagged) - Mouse discs, large homolog 4 (Drosophila) (Dlg4), transcript variant 1, (10ug) |
CNY 5,840.00 |
|
| MG227405 | Dlg4 (tGFP-tagged) - Mouse discs large homolog 4 (Drosophila) (Dlg4) transcript variant 1, (10ug) |
CNY 7,980.00 |
|
| MR227405L3 | Lenti ORF clone of Dlg4 (Myc-DDK-tagged) - Mouse discs, large homolog 4 (Drosophila) (Dlg4), transcript variant 1 |
CNY 9,120.00 |
|
| MR227405L4 | Lenti ORF clone of Dlg4 (mGFP-tagged) - Mouse discs, large homolog 4 (Drosophila) (Dlg4), transcript variant 1 |
CNY 9,120.00 |
