Il17rc (NM_178942) Mouse Tagged ORF Clone

Specifications

Product Data
Type	Mouse Tagged ORF Clone
Tag	Myc-DDK
Synonyms	1110025H02Rik; Gm19850; IL-17RC; IL17-RC; IL17-RL; Il17rl
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >MR230922 representing NM_178942 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCTGTGTCCTGGTTCCTGCTGTCCTTGGCACTGGGCCGAAACCCTGTGGTCGTCTCTCTGGAGAGAC TGATGGAGCCTCAGGACACTGCACGCTGCTCTCTAGGCCTCTCCTGCCACCTCTGGGATGGTGACGTGCT CTGCCTGCCTGGAAGCCTCCAGTCTGCCCCAGGCCCTGTGCTAGTGCCTACCCGCCTGCAGACGGAGCTG GTGCTGAGGTGTCCACAGAAGACAGATTGCGCCCTCTGTGTCCGTGTGGTGGTCCACTTGGCCGTGCATG GGCACTGGGCAGAGCCTGAAGAAGCTGGAAAGTCTGATTCAGAACTCCAGGAGTCTAGGAACGCCTCTCT CCAGGCCCAGGTGGTGCTCTCCTTCCAGGCCTACCCCATCGCCCGCTGTGCCCTGCTGGAGGTCCAGGTG CCCGCTGACCTGGTGCAGCCTGGTCAGTCCGTGGGTTCTGCGGTATTTGACTGTTTCGAGGCTAGTCTTG GGGCTGAGGTACAGATCTGGTCCTACACGAAGCCCAGGTACCAGAAAGAGCTCAACCTCACACAGCAGCT GCCTGACTGCAGGGGTCTTGAAGTCCGGGACAGCATCCAGAGCTGCTGGGTCCTGCCCTGGCTCAATGTG TCTACAGATGGTGACAATGTCCTTCTGACACTGGATGTCTCTGAGGAGCAGGACTTTAGCTTCTTACTGT ACCTGCGTCCAGTCCCGGATGCTCTCAAATCCTTGTGGTACAAAAACCTGACTGGACCTCAGAACATTAC TTTAAACCACACAGACCTGGTTCCCTGCCTCTGCATTCAGGTGTGGTCGCTAGAGCCAGACTCTGAGAGG GTCGAATTCTGCCCCTTCCGGGAAGATCCCGGTGCACACAGGAACCTCTGGCACATAGCCAGGCTGCGGG TACTGTCCCCAGGGGTATGGCAGCTAGATGCGCCTTGCTGTCTGCCGGGCAAGGTAACACTGTGCTGGCA GGCACCAGACCAGAGTCCCTGCCAGCCACTTGTGCCACCAGTGCCCCAGAAGAACGCCACTGTGAATGAG CCACAAGATTTCCAGTTGGTGGCAGGCCACCCCAACCTCTGTGTCCAGGTGAGCACCTGGGAGAAGGTTC AGCTGCAAGCGTGCTTGTGGGCTGACTCCTTGGGGCCCTTCAAGGATGATATGCTGTTAGTGGAGATGAA AACCGGCCTCAACAACACATCAGTCTGTGCCTTGGAACCCAGTGGCTGTACACCACTGCCCAGCATGGCC TCCACGAGAGCTGCTCGCCTGGGAGAGGAGTTGCTGCAAGACTTCCGATCACACCAGTGTATGCAGCTGT GGAACGATGACAACATGGGATCGCTATGGGCCTGCCCCATGGACAAGTACATCCACAGGCGCTGGGTCCT AGTATGGCTGGCCTGCCTACTCTTGGCTGCGGCGCTTTTCTTCTTCCTCCTTCTAAAAAAGGACCGCAGG AAAGCGGCCCGTGGCTCCCGCACGGCCTTGCTCCTCCACTCCGCCGACGGAGCGGGCTACGAGCGTCTGG TGGGAGCACTGGCGTCCGCGTTGAGCCAGATGCCACTGCGCGTGGCCGTGGACCTGTGGAGCCGCCGCGA GCTGAGCGCGCACGGAGCCCTAGCCTGGTTCCACCACCAGCGACGCCGTATCCTGCAGGAGGGTGGCGTG GTAATCCTTCTCTTCTCGCCCGCGGCCGTGGCGCAGTGTCAGCAGTGGCTGCAGCTCCAGACAGTGGAGC CCGGGCCGCATGACGCCCTCGCCGCCTGGCTCAGCTGCGTGCTACCCGATTTCCTGCAAGGCCGGGCGAC CGGCCGCTACGTCGGGGTCTACTTCGACGGGCTGCTGCACCCAGACTCTGTGCCCTCCCCGTTCCGCGTC GCCCCGCTCTTCTCCCTGCCCTCGCAGCTGCCGGCTTTCCTGGATGCACTGCAGGGAGGCTGCTCCACTT CCGCGGGGCGACCCGCGGACCGGGTGGAACGAGTGACCCAGGCGCTGCGGTCCGCCCTGGACAGCTGTAC TTCTAGCTCGGAAGCCCCAGGCTGCTGCGAGGAATGGGACCTGGGACCCTGCACTACACTAGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >MR230922 representing NM_178942 Red=Cloning site Green=Tags(s) MPVSWFLLSLALGRNPVVVSLERLMEPQDTARCSLGLSCHLWDGDVLCLPGSLQSAPGPVLVPTRLQTEL VLRCPQKTDCALCVRVVVHLAVHGHWAEPEEAGKSDSELQESRNASLQAQVVLSFQAYPIARCALLEVQV PADLVQPGQSVGSAVFDCFEASLGAEVQIWSYTKPRYQKELNLTQQLPDCRGLEVRDSIQSCWVLPWLNV STDGDNVLLTLDVSEEQDFSFLLYLRPVPDALKSLWYKNLTGPQNITLNHTDLVPCLCIQVWSLEPDSER VEFCPFREDPGAHRNLWHIARLRVLSPGVWQLDAPCCLPGKVTLCWQAPDQSPCQPLVPPVPQKNATVNE PQDFQLVAGHPNLCVQVSTWEKVQLQACLWADSLGPFKDDMLLVEMKTGLNNTSVCALEPSGCTPLPSMA STRAARLGEELLQDFRSHQCMQLWNDDNMGSLWACPMDKYIHRRWVLVWLACLLLAAALFFFLLLKKDRR KAARGSRTALLLHSADGAGYERLVGALASALSQMPLRVAVDLWSRRELSAHGALAWFHHQRRRILQEGGV VILLFSPAAVAQCQQWLQLQTVEPGPHDALAAWLSCVLPDFLQGRATGRYVGVYFDGLLHPDSVPSPFRV APLFSLPSQLPAFLDALQGGCSTSAGRPADRVERVTQALRSALDSCTSSSEAPGCCEEWDLGPCTTLE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_178942
ORF Size	2094 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_178942.1, NP_849273.1
RefSeq Size	2369 bp
RefSeq ORF	2097 bp
Locus ID	171095
UniProt ID	Q8K4C2
MW	77.6 kDa
Gene Summary	Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:17911633, PubMed:20554964). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (By similarity). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (By similarity).[UniProtKB/Swiss-Prot Function]

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