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Insulin Receptor R (INSRR) (NM_014215) Human Tagged ORF Clone
CAT＃: RC600011
- TrueORF®
INSRR (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens insulin receptor-related receptor, Signal peptide (1-26) plus EC domain (747-921)
"NM_014215" in other vectors (8)
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CNY 2,400.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | DDK-His |
| Synonyms | IRR |
| Vector | pCMV6-XL5-DDK-His |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>RC600011 representing leader sequence plus the extracellular domain region of NM_014215
Red=Cloning site Blue=ORF Green=Tags(s) GTAATACGACTCACTATAGGGCGGCCGCGAATTCGTCGACTGGATCTGGTACCGAGGAGATCCGCCGCCG CGATCGCC ATGGCAGTGCCTAGTCTGTGGCCCTGGGGAGCATGCCTGCCTGTGATCTTCCTCTCCTTGGGATTTGGCC TGGATACAGCAGCTGGGCCCCTCCGGCTGGGGGGCAACAGCTCGGATTTCGAGATCCAGGAGGACAAGGT GCCCCGTGAGCGAGCGGTGCTGAGCGGCCTGCGCCACTTCACGGAATACCGGATCGACATCCATGCCTGC AACCACGCGGCGCACACCGTGGGCTGCAGCGCCGCCACCTTCGTCTTTGCGCGCACCATGCCCCACAGAG AGGCTGATGGTATTCCAGGAAAGGTGGCCTGGGAGGCCTCCAGCAAGAACAGTGTCCTTCTGCGCTGGCT CGAGCCACCAGACCCCAACGGACTCATCCTCAAGTACGAAATCAAGTACCGCCGCTTGGGAGAGGAGGCC ACAGTGCTGTGTGTGTCCCGTCTTCGATATGCGAAGTTTGGGGGAGTCCACCTGGCCCTGCTGCCCCCTG GAAACTACTCTGCCAGGGTTAGGGCAACCTCACTGGCTGGCAATGGCTCTTGGACAGACAGTGTTGCCTT CTACATCCTTGGCCCAGAGGAGGAGGATGCTGGGGGGCTGCAT ACGCGTTCAGGCGACTACAAGGATGACGACGATAAGGGATCTCATCATCACCATCACCATTAATGAGATC TGGTACCGATATCAAGCTTGTCGACTCTAGA >RC600011 representing signal peptide plus the extracellular domain region of NM_014215
Red=Cloning sites Green= DDK and 6XHIS Tags MAVPSLWPWGACLPVIFLSLGFGLDTAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFTEYRIDIHAC NHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEA TVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLH TRSGTRSGDYKDDDDKGSHHHHHH |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
| ACCN | NM_014215 |
| ORF Size | 603 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the extra cellular domain of the protein with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014215.2, NP_055030.1 |
| RefSeq Size | 4193 bp |
| RefSeq ORF | 3894 bp |
| Locus ID | 3645 |
| UniProt ID | P14616 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Prostate cancer, Regulation of actin cytoskeleton |
| MW | 21.9 kDa |
| Gene Summary | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224956 | INSRR (Myc-DDK-tagged)-Human insulin receptor-related receptor (INSRR) |
CNY 9,032.00 |
|
| RC224956L1 | Lenti ORF clone of Human insulin receptor-related receptor (INSRR), Myc-DDK-tagged |
CNY 11,432.00 |
|
| RC224956L2 | Lenti ORF clone of Human insulin receptor-related receptor (INSRR), mGFP tagged |
CNY 14,820.00 |
|
| RC224956L3 | Lenti ORF clone of Human insulin receptor-related receptor (INSRR), Myc-DDK-tagged |
CNY 14,820.00 |
|
| RC224956L4 | Lenti ORF clone of Human insulin receptor-related receptor (INSRR), mGFP tagged |
CNY 14,820.00 |
|
| RG224956 | INSRR (tGFP-tagged) - Human insulin receptor-related receptor (INSRR) |
CNY 14,250.00 |
|
| SC315340 | INSRR (untagged)-Human insulin receptor-related receptor (INSRR) |
CNY 25,080.00 |
|
| SC323604 | INSRR (untagged)-Kinase deficient mutant (K1013M) of Human insulin receptor-related receptor (INSRR) |
CNY 9,040.00 |
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