USP37 (NM_020935) Human Untagged Clone
CAT＃: SC107387
USP37 (untagged)-Human ubiquitin specific peptidase 37 (USP37)
CNY 7176.00
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC107387 sequence for NM_020935 edited (data generated by NextGen Sequencing)
ATGTCTCCTCTGAAGATACATGGTCCTATCAGAATTCGAAGTATGCAGACTGGGATTACA AAGTGGAAAGAAGGATCCTTTGAAATTGTAGAAAAAGAGAATAAAGTCAGCCTAGTAGTT CACTACAATACTGGAGGAATTCCAAGGATATTTCAGCTAAGTCATAACATTAAAAATGTG GTGCTTCGACCCAGTGGAGCGAAACAAAGCCGCCTAATGTTAACTCTGCAAGATAACAGC TTCTTGTCTATTGACAAAGTACCAAGTAAGGATGCAGAGGAAATGAGGTTGTTTCTAGAT GCAGTCCATCAAAACAGACTTCCTGCAGCCATGAAACCGTCTCAGGGGTCTGGTAGTTTT GGAGCCATTCTGGGCAGCAGGACCTCACAGAAGGAAACCAGCAGGCAGCTTTCTTACTCA GACAATCAGGCTTCTGCAAAAAGAGGAAGTTTGGAAACTAAAGATGATATTCCATTTCGA AAAGTTCTTGGTAATCCGGGTAGAGGATCGATTAAGACTGTAGCAGGAAGTGGAATAGCT CGGACGATTCCTTCTTTGACATCTACTTCAACACCTCTTAGATCAGGGTTGCTAGAAAAT CGTACTGAAAAGAGGAAAAGAATGATATCAACTGGCTCAGAATTGAATGAAGATTACCCT AAGGAAAATGATTCATCATCGAACAACAAGGCCATGACAGATCCCTCCAGAAAGTATTTA ACCAGCAGTAGAGAAAAGCAGCTGAGTTTGAAACAGTCAGAAGAGAATAGGACATCAGGG CTTTTACCTTTACAGTCATCATCCTTTTATGGTAGCAGAGCTGGATCCAAGGAACACTCT TCTGGTGGCACTAACTTAGACAGGACTAATGTTTCAAGCCAGACTCCCTCTGCCAAAAGA AGTTTGGGATTTCTTCCTCAGCCAGTTCCTCTTTCTGTTAAAAAACTGAGGTGTAACCAG GATTACACTGGCTGGAATAAACCAAGAGTGCCCCTTTCCTCTCACCAACAGCAGCAACTG CAGGGCTTCTCCAATTTGGGAAATACCTGCTATATGAATGCTATTCTACAATCTCTATTT TCACTCCAGTCATTTGCAAATGACTTGCTTAAACAAGGTATCCCATGGAAGAAAATTCCA CTCAATGCACTTATCAGACGCTTTGCACACTTGCTTGTTAAAAAAGATATCTGTAATTCA GAGACCAAAAAGGATTTACTCAAGAAGGTTAAAAATGCCATTTCAGCTACAGCAGAGAGA TTCTCTGGTTATATGCAGAATGATGCTCATGAATTTTTAAGTCAGTGTTTGGACCAGCTG AAAGAAGATATGGAAAAATTAAATAAAACTTGGAAGACTGAACCTGTTTCTGGAGAAGAA AATTCACCAGATATTTCAGCTACCAGAGCATACACTTGCCCTGTTATTACTAATTTGGAG TTTGAGGTTCAGCACTCCATCATTTGTAAAGCATGTGGAGAGATTATCCCCAAAAGAGAA CAGTTTAATGACCTCTCTATTGACCTTCCTCGTAGGAAAAAACCACTCCCTCCTCGTTCA ATTCAAGATTCTCTTGATCTTTTCTTTAGGGCCGAAGAACTGGAGTATTCTTGTGAGAAG TGTGGTGGGAAGTGTGCTCTTGTCAGGCACAAATTTAACAGGCTTCCTAGGGTCCTCATT CTCCATTTGAAACGATATAGCTTCAATGTGGCTCTCTCGCTTAACAATAAGATTGGGCAG CAAGTCATCATTCCAAGATACCTGACCCTGTCATCTCATTGCACTGAAAATACAAAACCA CCTTTTACCCTTGGTTGGAGTGCACATATGGCAATTTCTAGACCATTGAAAGCCTCTCAA ATGGTGAATTCCTGCATCACCAGCCCTTCTACACCTTCAAAGAAATTCACCTTCAAATCC AAGAGCTCCTTGGCTTTATGCCTTGATTCAGACAGTGAGGATGAGCTAAAACGTTCTGTG GCCCTCAGCCAGAGACTTTGTGAAATGTTAGGCAACGAACAGCAGCAGGAAGACCTGGAA AAAGATTCAAAATTATGCCCAATAGAGCCTGACAAGTCTGAATTGGAAAACTCAGGATTT GACAGAATGAGCGAAGAAGAGCTTCTAGCAGCTGTCTTGGAGATAAGTAAGAGAGATGCT TCACCATCTCTGAGTCATGAAGATGATGATAAGCCAACTAGCAGCCCAGATACCGGATTT GCAGAAGATGATATTCAAGAAATGCCAGAAAATCCAGACACTATGGAAACTGAGAAGCCC AAAACAATCACAGAGCTGGATCCTGCCAGTTTTACTGAGATAACTAAAGACTGTGATGAG AATAAAGAAAACAAAACTCCAGAAGGATCTCAGGGAGAAGTTGATTGGCTCCAGCAGTAT GATATGGAGCGTGAAAGGGAAGAGCAAGAGCTTCAGCAGGCACTGGCTCAGAGCCTTCAA GAGCAAGAGGCTTGGGAACAGAAAGAAGATGATGACCTCAAAAGAGCTACCGAGTTAAGT CTTCAAGAGTTTAACAACTCCTTTGTGGATGCATTGGGTTCTGATGAGGACTCTGGAAAT GAGGATGTTTTTGATATGGAGTACACAGAAGCTGAAGCTGAGGAACTGAAAAGAAATGCT GAGACAGGAAATCTGCCTCATTCGTACCGGCTCATCAGTGTTGTCAGTCACATTGGTAGC ACTTCTTCTTCAGGTCATTACATTAGTGATGTATATGACATTAAGAAGCAAGCGTGGTTT ACTTACAATGACCTGGAGGTATCAAAAATCCAAGAGGCTGCCGTGCAGAGTGATCGAGAT CGGAGTGGCTACATCTTCTTTTATATGCACAAGGAGATCTTTGATGAGCTGCTGGAAACA GAAAAGAACTCTCAGTCACTTAGCACGGAAGTGGGGAAGACTACCCGTCAGGCCTCGTGA Clone variation with respect to NM_020935.2 >OriGene 5' read for NM_020935 unedited
TTCCCCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA ATTCGGCACGAGGCCGCCATCAGCCGCTCTCCCTGACTAGGGGTAGCTAGCGGCCTCCCT CCTTTGGGTTCTGTATCCCTACTTCCATTACCCTCGGCTCCTCCCACTCCTCGGGGGCTC CGTGCTTTCCGCGGGTCTGTCCGGGGGCTCCGGACCCTCGGCGCAGCTGAGTTGATGGCT TCCGGAGAACTGGCATAGCTGCAGAATATGAGTAGTGTCCCAAGAAGAGTGCTTTGCCTT TGGCACAAGGATCAGAATAAAGGTGAATTGCTATTACATAGGGTTTTTCGGTAAAAGTCA CTGAAAATTATTTGCCATACAGTAACCAGAGACCTCCAACTAGGGGCCCCCAAACTGTAT CCTGCCTGTAGCCAGAAGCAATTTTTAAAGAAAATATGTCTCCTCTGAAGATACATGGTC CTATCAGAATTCGAAGTATGCAGACTGGGATTACAAAGTGGAAAGAAGGATCCTTTGAAA TTGTAGAAAAAGAGAATAAGTCAAGCTAGTAGTTCACTACAATACTGGAGGGAATTCCAG GATAATTCAGCTAAGGCATAACATTAAAAAGGTGGTGCTTCAACCCAGTGGAGCGAAACA AAAGCCGCCTATGGTAACCTCTGCAGAAACCAGCTTCTTGCTTATTGCCAAAGTACCCCA GTAGGATGCCCACGGAAATGAGGTTGTTTCTAGAAGCAGTCCATTAAAACAGACTTCCTG CAGCCATGAAACCGTCTAAGGGTCTGGAAGTTTTGGGGCCTTCTGGGCCGCGGGACCCCC CCGAGGAAACCCCCCGGCAGCTTTTTACTCCACAATCAGGCTCTGGCCAAAAGG >OriGene 3' read for NM_020935 unedited
AGAAATTCCCTCATGTGATGGTGGGTTTTTAAATGTTTTTTCCTTCTGAAAACCTGATGT GGCTTTGTCCCTCCCCCTGATATCTTTTGAATAATCCCCTTGTTTATCATAAAAGAAAAA ACACAAAAATTCCCTCGTGGNNNCACTTTTCNATTTTTTTCTCTGGGTGATCCTAATGAT ATCTGGGCTCACAAAATTATTTTGTGGACAGAATTTTCTCCTCCAAAGAATTCTTTATCT GGCTTCATAAGCTGCCCACCCTAGCTGGTTACGTCCCCTTAGCGACTAGCCTANCACTTA CTGTTGCCGCTCCTCTTTGCCTCCCCTCAGAGCACCCTTCTTGCTCCTCACTTAATTATG CACCTCTGTCATCTGTTAGTTTTTGGGATTACCTCCGCCCATCCCCTTTTATTTGCCACC CTCCTTTAAGGGCTTAGCCCGACAGTGTGTGGCTNAATGCCCAAGGTTTGTCCCTTNGGC TCTGTACTTACCTTCCCACTTGCCCTCNGGCCTCTTTTCTCCTGTGGTCCCGAATTTTAG CTTTCCCCTCCCAACCCTCCTCCTTATCCTCCCTCTGTTTGGCCGACCGATATTGCTATC TTCTTCCCTTTCCCTATCTATTCCTGCTGGGGGTTTTCATTTGGGGCTATCTTTCCTCCC CAATTTGTTTTACGTCTTTGGCGCCCCCCCTCTTTTGTCCTGCCTGCCTCCCGGGTTGTT TGCCCCCGCAGATAAGAGTTCCTTCGTTCCCGCCCCTGTTTTCGCGTACGGCCCTGCAGG TATCTCCCCGTGGGACCAACCCCCCAAAAAAAAAAAGAAAAACAGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_020935 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020935.1, NP_065986.1 |
| RefSeq Size | 8015 bp |
| RefSeq ORF | 2940 bp |
| Locus ID | 57695 |
| UniProt ID | Q86T82 |
| Protein Families | Protease |
| Gene Summary | Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223407 | USP37 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 37 (USP37) |
CNY 7168.00 |
|
| RC223407L1 | Lenti ORF clone of Human ubiquitin specific peptidase 37 (USP37), Myc-DDK-tagged |
CNY 9568.00 |
|
| RC223407L2 | Lenti ORF clone of Human ubiquitin specific peptidase 37 (USP37), mGFP tagged |
CNY 5890.00 |
|
| RC223407L3 | Lenti ORF clone of Human ubiquitin specific peptidase 37 (USP37), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC223407L4 | Lenti ORF clone of Human ubiquitin specific peptidase 37 (USP37), mGFP tagged |
CNY 5890.00 |
|
| RG223407 | USP37 (tGFP-tagged) - Human ubiquitin specific peptidase 37 (USP37) |
CNY 8768.00 |
