IL15RA (NM_002189) Human Untagged Clone
CAT＃: SC109344
IL15RA (untagged)-Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1
CNY 2400.00
CNY 6270.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD215 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109344 sequence for NM_002189 edited (data generated by NextGen Sequencing)
ATGGCCCCGCGGCGGGCGCGCGGCTGCCGGACCCTCGGTCTCCCGGCGCTGCTACTGCTG CTGCTGCTCCGGCCGCCGGCGACGCGGGGCATCACGTGCCCTCCCCCCATGTCCGTGGAA CACGCAGACATCTGGGTCAAGAGCTACAGCTTGTACTCCAGGGAGCGGTACATTTGTAAC TCTGGTTTCAAGCGTAAAGCCGGCACGTCCAGCCTGACGGAGTGCGTGTTGAACAAGGCC ACGAATGTCGCCCACTGGACAACCCCCAGTCTCAAATGCATTAGAGACCCTGCCCTGGTT CACCAAAGGCCAGCGCCACCCTCCACAGTAACGACGGCAGGGGTGACCCCACAGCCAGAG AGCCTCTCCCCTTCTGGAAAAGAGCCCGCAGCTTCATCTCCCAGCTCAAACAACACAGCG GCCACAACAGCAGCTATTGTCCCGGGCTCCCAGCTGATGCCTTCAAAATCACCTTCCACA GGAACCACAGAGATAAGCAGTCATGAGTCCTCCCACGGCACCCCCTCTCAGACAACAGCC AAGACCTGGGAACTCACAGCATCCGCCTCCCACCAGCCGCCAGGTGTGTATCCACAGGGC CACAGCGACACCACTGTGGCTATCTCCACGTCCACTGTCCTGCTGTGTGGGCTGAGCGCT GTGTCTCTCCTGGCATGCTACCTCAAGTCAAGGCAAACTCCCCCGCTGGCCAGCGTTGAA ATGGAAGCCATGGAGGCTCTGCCGGTGACTTGGGGGACCAGCAGCAGAGATGAAGACTTG GAAAACTGCTCTCACCACCTATGA Clone variation with respect to NM_002189.3 545 a=>c >OriGene 5' read for NM_002189 unedited
GGATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGGGAGTCCAGC GGTGTCCTGTGGAGCTGCCGCCATGGCCCCGCGGCGGGCGCGCGGCTGCCGGACCCTCGG TCTCCCGGCGCTGCTACTGCTGCTGCTGCTCCGGCCGCCGGCGACGCGGGGCATCACGTG CCCTCCCCCCATGTCCGTGGAACACGCAGACATCTGGGTCAAGAGCTACAGCTTGTACTC CAGGGACCGGTACATTTGTAACTCTGGTTTCAAGCGTAAAGCCGGCACGTCCAGCCTGAC GGAGTGCGTGTTGAACAAGGCCACGAATGTCGCCCACTGGACAACCCCCAGTCTCAAATG CATTAGAGACCCTGCCCTGGTTCACCAAAGGCCAGCGCCACCCTCCACAGTAACGACGGC AGGGGTGACCCCACAGCCAGAGAGCCTCTCCCCTTCTGGAAAAGAGCCCGCAGCTTCATC TCCCAGCTCAAACAACACAGCGGCCACAACAGCAGCTATTGTCCCGGGCTCCCAGCTGAT GCCTTCAAAATCACCTTCCACAGGAACCACAGAGATAAGCAGTCATGAGTCCTCCCACGG CACCCCCTCTCAGACAACAGCCAAGACCTGNGAACTCACAGCATCCGCCTCCCACCAGCC GCCAGGTGTGTATCCACAGGGCCACAGCGACACCACTGTGGCTATCTCCACGTCCACTGT CCTGCTGTGTGGGCTGAGCGCTGTGTCTCTCCTGGCATGCTACCTCAAGTCAAGGCANAC TCCCCCCGCTGCCAGCGTTGAAATGGAAGCCATGGNAGCTCTGNNCGTGACTTGNGGGAC CAGCAGCAGAGATGAAGACTTGGAANACTGCTCTCACACCTATGAAACTCGNGAAACCAG NCCAGCTAGTCCGNAGTGAGGAGCTCTCTGCTTTACTAAGACACTGAAAGAGTGCAGGAA GCGGNCTCAGACAGCTACCAGCNTAAAGTCCACAGATTACGACTGTCGGTCGGCCT >OriGene 3' read for NM_002189 unedited
AAGGAGGCGCCTAGGNGAATGGCACTTTCCAGGNCCAGNAAAGCACTGGGGNAGGGTCAC AGGATGCCACCCGGGAATTCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAG TCGAGTTTTTTTTTTTTTTTTTTTATTGAAAATAGATGTTTTATTTTGTTTATACAAGGT ACAATGTCAAAATACAAATAATATATAATGTATAGATATAATAGACAAGGAAGTATAAAT ATAAACGCATATATTCGTAAAATGGCACTGAGTTGAGTTTTCTTCTTCCTGAATCCTTCA ATGGAGAGGATTCGCTGGGCTCAGCATCTCTCCCACCTTTCCCAGGTCCCTGTCCATGTG TGCAGAGCAGCTGGAGACAGGGTGGTTAGAAGCCCAAACGCTGGTGTCTTCCCTGTAGAC GTCTCCCACGCCAGGAGAAGCCTTGTAATTGACAGAGAGCTTTGGGTATGTCACTTTTCT CTGTGAACTGCAAGTTAGGATGAGGGACGGAAGATTCGGGGCAGGGTTTTCATTTCATCA CCACATGTATTCCAAGCAGCTCACACTGTAATGAAATAAAAATCCTGCTCAGAAGCCTTT GGTCTCTCCTGGGAAGCTGGGCCCTGGGTCCAAGGCACGACAGGCAGGCAAGTGGTGCCC ATGGGAAAGCGGAGAACCTGCTCCTTCGCGCAGGAAGCGCCGAACCCGCAGTCCGGGAAT CCTGCTGGAATTTTAAAAAGCCTGGTGAACTTGTTCCTGAAACCCGCCTCATTGCAACTA TTTCTAATACACTTTTACTAAAGCAAAAAAGCTCCTTTTTTCCCAAATTATCTTGGATGG CTTCACCAAATTTTAAAATTGTGGAGAACATTTTCCACAGTCTCACTTGN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002189 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002189.2, NP_002180.1 |
| RefSeq Size | 1610 bp |
| RefSeq ORF | 804 bp |
| Locus ID | 3601 |
| UniProt ID | Q13261 |
| Domains | CCP |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
| Gene Summary | This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010] Transcript Variant: This variant (1) lacks an alternate in-frame 5' coding exon, compared to variant 4. This results in a shorter isoform (1), compared to isoform 4. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211921 | IL15RA (Myc-DDK-tagged)-Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1 |
CNY 2400.00 |
|
| RC211921L1 | Lenti ORF clone of Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1, Myc-DDK-tagged |
CNY 4800.00 |
|
| RC211921L2 | Lenti ORF clone of Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1, mGFP tagged |
CNY 4800.00 |
|
| RC211921L3 | Lenti ORF clone of Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC211921L4 | Lenti ORF clone of Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1, mGFP tagged |
CNY 4800.00 |
|
| RG211921 | IL15RA (tGFP-tagged) - Human interleukin 15 receptor, alpha (IL15RA), transcript variant 1 |
CNY 4000.00 |
