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TXNDC (TMX1) (NM_030755) Human Untagged Clone
CAT＃: SC109735
TMX1 (untagged)-Human thioredoxin-related transmembrane protein 1 (TMX1)
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PDIA11; TMX; TXNDC; TXNDC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109735 sequence for NM_030755 edited (data generated by NextGen Sequencing)
ATGGCGCCCTCCGGGAGTCTTGCAGTTCCCCTGGCAGTCCTGGTGCTGTTGCTTTGGGGT GCTCCCTGGACGCACGGGCGGCGGAGCAACGTTCGCGTCATCACGGACGAGAACTGGAGA GAACTGCTGGAAGGAGACTGGATGATAGAATTTTATGCCCCGTGGTGCCCTGCTTGTCAA AATCTTCAACCGGAATGGGAAAGTTTTGCTGAATGGGGAGAAGATCTTGAGGTTAATATT GCGAAAGTAGATGTCACAGAGCAGCCAGGACTGAGTGGACGGTTTATCATAACTGCTCTT CCTACTATTTATCATTGTAAAGATGGTGAATTTAGGCGCTATCAGGGTCCAAGGACTAAG AAGGACTTCATAAACTTTATAAGTGATAAAGAGTGGAAGAGTATTGAGCCCGTTTCATCA TGGTTTGGTCCAGGTTCTGTTCTGATGAGTAGTATGTCAGCACTCTTTCAGCTATCTATG TGGATCAGGACGTGCCATAACTACTTTATTGAAGACCTTGGATTGCCAGTGTGGGGATCA TATACTGTTTTTGCTTTAGCAACTCTGTTTTCCGGACTGTTATTAGGACTCTGTATGATA TTTGTGGCAGATTGCCTTTGTCCTTCAAAAAGGCGCAGACCACAGCCATACCCATACCCT TCAAAAAAATTATTATCAGAATCTGCACAACCTTTGAAAAAAGTGGAGGAGGAACAAGAG GCGGATGAAGAAGATGTTTCAGAAGAAGAAGCTGAAAGTAAAGAAGGAACAAACAAAGAC TTTCCACAGAATGCCATAAGACAACGCTCTCTGGGTCCATCATTGGCCACAGATAAATCC TAG Clone variation with respect to NM_030755.4 492 t=>g;648 g=>a >OriGene 5' read for NM_030755 unedited
CCAGTCAGCAATTGTATACGACTCATATAGGCGGCCGCTGAATTCGCACGAGGCAGCCCG CGAGGGCGGAAGTGGGAGCTGCGACCGCGCTCCCTGTGAGGTGGGCAAGCGGCGAAATGG CGCCCTCCGGGAGTCTTGCAGTTCCCCTGGCAGTCCTGGTGCTGTTGCTTTGGGGTGCTC CCTGGACGCACGGGCGGCGGAGCAACGTTCGCGTCATCACGGACGAGAACTGGAGAGAAC TGCTGGAAGGAGACTGGATGATAGAATTTTATGCCCCGTGGTGCCCTGCTTGTCAAAATC TTCAACCGGAATGGGAAAGTTTTGCTGAATGGGGAGAAGATCTTGAGGTTAATATTGCGA AAGTAGATGTCACAGAGCAGCCAGGACTGAGTGGACGGTTTATCATAACTGCTCTTCCTA CTATTTATCATTGTAAAGATGGTGAATTTAGGCGCTATCAGGGTCCAAGGACTAAGAAGG ACTTCATAAACTTTATAAGTGATAAAGAGTGGAAGAGTATTGAGCCCGTTTCATCATGGT TTGGTCCAGGTTCTGTTCTGATGAGTAGTATGTCAGCACTCTTTCAGCTATCTATGTGGA TCAGGACGTGCCATAACTACTTTATTGAAGACCTTGGATTGCCAGTGTGGGGATCATATA CTGTTTTTGCTTTAGCAACTCTGTTTTCCGGACTGTTATTAGGACTCTGTATGATATTTG TGGCAGATTGCCTTTGTCCTTCAAAAAGGCGCAGACCACAGCCATACCCATACTCTTTAG AAACATTATTATCAGAATCTGCACACCTTTTGAAAAAAGTGGAGAGGAACAAGAGGCTGA TGAAGAAGATGTTTCACACGAGCAGCTGAAAGTAAAGAGGAACAAACAAGACTTTCCCAA ATGCCATAGA >OriGene 3' read for NM_030755 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAAAAGGGGTAAAAAGGGTTTTTTTGGGCT TAAGAATTTTTTTTAAGGGCTCACAAGTTCCCCCTCCAAACTTTTTAAGGGGCCAATTTT TTAAATTTTAAAGGAAAGGGCTTTAAAAAAAACTTTTTTTTTCCCAACCCGGAAATTTAA GGGGTTCCCCCCCCACCAAACCCTAAAAAAAAGGGGCCCTTTCCAAAATTGCCTCCCCCC AAAGGGGCAAGGGATTCATTGGATTTAAAAATTCCCCCCTTTTTTTAAGGGGAAAACTTT TTTTTTTACCTTTTTAAGGGGAAAAAACCCCCCAAAAGGGCCCCCCCCCCCGCCTTTTCC CCGGGAAACCCCCCCCCATTTTCCCCCCCCGGAAAAAACCCCGGGTAATTTGAAGTTTGT CTTTTAAAAAATAAAAAAATGTTTTTTTTTTAAAACATCAACCCTTCCCACCTGGAAAAA CAATTAAAAACCTTTTGTTTTTGAGGGCCAAAATACCTTTAAAACATTTACCAAAAAAAG CTTTTTCCTGAAAAAAAAGCAAACTTTTATTTTAACCCTTTTTGAATTTTCAAAATGGAA AACACCAAGGGTTTTTCCCCTTAAACAAAAATCTCGAATGGCTCCCCTTCCCCCCCCAAA AGAAAAAAACAAAAAAACCACTTCTCAGTTGAAGCTCCCCCAGAAAGGTTGAAAATTTCA GAAAAAGGGCCCCAAATTTTAAATTACCCCACAAATTGTCCAATTTGGAGGGAGTCCTCC ACAAACCCCTTANTTTGAAAACACACAAAAAAACCTGGCTACTTAAAACATAAAAAATGT TCCCAAAAATTTTCTCTCCCTTTGAAAATAAAAAGGCCCCCTTTTGGTTAGAAAACACCG GAAAATC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_030755 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_030755.3, NP_110382.2 |
| RefSeq Size | 2473 bp |
| RefSeq ORF | 843 bp |
| Locus ID | 81542 |
| UniProt ID | Q9H3N1 |
| Domains | thiored |
| Protein Families | Druggable Genome, Transcription Factors, Transmembrane |
| Gene Summary | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Reductive Activation of Type 2 Ribosome-inactivating Proteins Is Promoted by Transmembrane Thioredoxin-related Protein
,Matteo Pasetto, Erika Barison, Monica Castagna, Pietro Della Cristina, Cristina Anselmi, and Marco Colombatti,
J. Biol. Chem., Mar 2012; 287: 7367 - 7373.
[TMX1]
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