FHOD3 (NM_025135) Human Untagged Clone
CAT＃: SC110946
FHOD3 (untagged)-Human formin homology 2 domain containing 3 (FHOD3)
CNY 3656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMH28; FHOS2; Formactin2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_025135, the custom clone sequence may differ by one or more nucleotides
ATGGCCACGCTGGCTTGCCGGGTGCAGTTCTTGGACGACACGGACCCTTTCAACAGCACCAACTTCCCCG AGCCCAGCCGGCCGCCGCTGTTCACGTTCCGCGAGGACCTCGCGCTCGGCACCCAGCTGGCGGGGGTCCA TAGGCTGCTGCAGGCGCCGCACAAGCTGGATGACTGTACTCTGCAGCTCTCTCACAATGGCGCCTACCTG GATTTGGAGGCCACCCTGGCAGAGCAGCGGGATGAGTTGGAAGGCTTCCAGGATGACGCCGGGCGGGGCA AGAAGCACAGCATCATCCTAAGGACGCAGCTGTCTGTGAGGGTCCATGCCTGCATCGAAAAACTATACAA CTCCAGCGGACGAGATTTGAGAAGGGCCCTCTTCTCCCTGAAGCAGATATTTCAGGATGACAAGGATTTG GTGCATGAATTTGTAGTGGCTGAAGGTCTGACATGTTTGATCAAGGTGGGAGCTGAGGCTGATCAGAACT ATCAGAACTACATCTTAAGGGCTTTGGGCCAGATTATGTTGTATGTGGATGGAATGAATGGAGTAATAAA CCGCAATGAAACCATTCAGTGGCTGTACACTCTCATTGGGTCAAAGTTCCGCCTGGTGGTGAAGACAGCC CTGAAGCTGCTGCTCGTCTTTGTAGAGTACTCGGAGTCCAACGCACCTCTCCTAATTCAGGCTGTCACTG CTGTTGACACGAAAAGAGGGGTCAAACCTTGGTCAAATATCATGGAAATCCTGGAGGAAAAAGATGGAGT TGATACGGAGCTACTGGTTTATGCAATGACTTTGGTGAACAAGACGTTATCAGGACTACCAGACCAAGAC ACCTTCTACGACGTCGTGGACTGCCTGGAGGAGCTGGGCATTGCTGCTGTGTCCCAGAGGCACTTGAACA AGAAAGGGACTGACCTGGACTTAGTGGAGCAACTCAACATTTATGAGGTGGCGCTCAGGCACGAGGATGG CGATGAGACCACGGAGCCACCCCCCAGTGGGTGCCGGGACCGGAGGAGGGCCAGCGTGTGTTCCAGTGGC GGAGGCGAGCACCGGGGCCTGGACCGCAGAAGGAGCCGCAGGCACTCGGTGCAGAGCATCAAGAGCACCC TGTCGGCCCCCACCAGTCCCTGCTCCCAGTCAGCTCCCAGCTTCAAGCCCAACCAAGTGCGAGATCTGCG TGAAAAATACAGCAATTTTGGCAATAACTCTTATCACTCCTCAAGACCCTCATCTGGATCCAGTGTGCCC ACCACCCCCACATCATCCGTCTCACCCCCACAGGAGGCCAGGTTGGAAAGGTCATCACCGAGTGGTCTTC TCACATCATCCTTCAGGCAGCACCAAGAGTCACTGGCAGCAGAGAGAGAGAGGCGGCGGCAGGAGAGAGA AGAAAGGTTGCAGAGAATAGAGCGGGAAGAAAGAAACAAATTCAGCCGAGATTATTTAGACAAAAGAGAG GAGCAAAGGCAAGCAAGAGAAGAAAGATACAAATACTTGGAACAGTTGGCAGCTGAGGAGCACGAGAAGG AGCTGAGAAGCCGGAGTGTGAGCCGGGGCAGAGCCGACCTCTCCTTGGACCTGACCTCGCCAGCAGCCCC AGCCTGCCTGGCTCCTCTGAGCCATAGCCCCTCATCTTCAGACTCTCAAGAGGCTCTCACGGTGTCTGCC TCCTCCCCAGGAACCCCTCACCATCCCCAAGCAAGTGCCGGGGATCCTGAACCCGAATCAGAGGCAGAAC CGGAAGCAGAGGCAGGGGCGGGGCAGGTTGCTGATGAAGCTGGCCAGGACATAGCCTCTGCCCACGAGGG TGCAGAGACTGAAGTGGAGCAGGCACTAGAGCAAGAGCCGGAAGAAAGAGCCTCCCTCAGTGAAAAAGAG AGGCAGAACGAGGGGGTGAACGAGAGGGACAACTGCTCTGCCTCCAGCGTCTCGTCCTCCAGCAGCACGT TGGAGAGGGAGGAGAAGGAGGACAAGCTCTCCAGGGACAGGACAACTGGTTTGTGGCCCGCAGGTGTCCA GGATGCAGGTGTAAATGGACAGTGTGGCGACATCCTCACCAACAAACGGTTCATGCTTGACATGCTGTAT GCCCATAACAGGAAGTCTCCGGATGATGAGGAGAAGGGGGATGGGGAGGCTGGGAGGACCCAGCAGGAGG CAGAGGCGGTAGCCAGCCTTGCTACCAGGATATCCACCCTGCAGGCCAACTCTCAGACCCAGGATGAGAG TGTCAGGAGGGTGGATGTCGGCTGTTTGGACAATCGGGGCAGTGTGAAAGCATTTGCTGAGAAATTCAAC AGTGGGGACCTGGGGAGAGGTTCCATCTCCCCTGATGCTGAGCCCAATGACAAGGTCCCAGAAACAGCGC CGGTGCAGCCGAAGACAGAGTCTGATTACATCTGGGACCAGCTCATGGCCAATCCAAGAGAGCTCAGAAT CCAAGACATGGATTTCACTGACCTGGGGGAGGAGGATGACATTGATGTCCTAGATGTGGACCTGGGTCAC AGGGAGGCCCCTGGGCCACCTCCCCCACCCCCACCCACCTTTCTGGGTTTGCCGCCCCCACCCCCTCCGC CCCTGTTGGACAGCATTCCTCCCCCTCCTGTCCCTGGTAATTTATTGGTTCCTCCTCCTCCAGTGTTCAA CGCTCCTCAGGGCTTAGGGTGGTCCCAGGTACCCAGGGGTCAGCCCACATTCACTAAGAAAAAGAAGACC ATCCGTTTGTTCTGGAATGAAGTTCGGCCTTTTGACTGGCCATGTAAAAACAACCGACGCTGCAGAGAAT TCCTGTGGTCAAAACTGGAACCCATTAAGGTGGACACTTCCAGACTGGAGCACCTGTTTGAGTCTAAATC CAAGGAACTGTCTGTCTCAAAGAAAACTGCTGCAGATGGAAAAAGGCAAGAGATCATTGTTCTGGATTCC AAGAGGAGTAACGCCATCAATATTGGTCTGACGGTGCTGCCCCCTCCAAGGACGATTAAGATCGCCATTT TGAATTTTGATGAGTATGCCTTAAACAAAGAAGGAATCGAGAAAATTCTAACGATGATTCCCACCGATGA GGAGAAGCAGAAAATCCAGGAAGCTCAGCTGGCCAACCCTGAAATCCCCCTGGGCAGTGCAGAGCAGTTC CTCCTCACCCTGTCCTCCATCAGCGAGCTCTCTGCACGACTTCACCTCTGGGCATTCAAAATGGATTATG AAACTACAGAAAAGGAAGTAGCAGAACCACTCCTGGACCTGAAGGAAGGAATAGACCAGTTGGAGAACAA TAAAACCTTGGGCTTTATCCTGTCTACTCTCTTAGCCATTGGGAACTTTCTAAATGGAACTAATGCCAAA GCGTTTGAGTTAAGCTACCTCGAGAAGGTTCCAGAAGTCAAAGACACAGTGCACAAGCAGTCGCTTCTCC ACCATGTGTGCACCATGGTGGTAGAAAACTTCCCAGACAGCTCCGATCTGTACTCGGAGATCGGGGCCAT CACCAGGTCAGCCAAGGTTGACTTTGATCAACTTCAGGATAATTTATGTCAGATGGAGAGAAGATGCAAA GCTTCATGGGATCACCTCAAGGCAATTGCAAAACATGAAATGAAACCAGTTTTAAAACAACGGATGTCAG AGTTCCTGAAAGACTGTGCAGAGCGAATTATAATTTTAAAGATTGTCCATAGAAGGATAATCAACAGATT CCACTCCTTTTTACTCTTTATGGGCCATCCACCTTATGCAATTCGGGAAGTGAACATAAACAAATTCTGC AGGATTATTAGTGAATTTGCACTAGAGTATCGCACAACCAGGGAAAGGGTTTTGCAGCAGAAACAGAAAC GGGCCAACCACAGAGAGAGAAATAAGACCAGAGGGAAGATGATCACCGATTCTGGCAAGTTCTCCGGCAG TTCTCCGGCGCCCCCAAGCCAGCCGCAGGGTCTGAGCTATGCGGAGGACGCGGCTGAGCACGAGAACATG AAGGCTGTGCTGAAAACCTCGTCCCCCTCCGTGGAGGACGCCACCCCCGCGCTGGGCGTCCGCACACGCA GCCGAGCAAGCCGAGGATCCACTAGTTCCTGGACTATGGGAACTGATGACTCGCCCAATGTCACAGATGA TGCAGCTGATGAGATCATGGACCGCATCGTCAAGTCAGCCACCCAAGTGCCCAGTCAGCGAGTGGTGCCG AGGGAGAGGAAACGATCCCGGGCCAACCGGAAATCTTTGCGAAGAACCCTGAAGAGCGGCCTGACCCCAG AAGAAGCCAGAGCCCTGGGCTTGGTTGGCACCTCGGAGTTGCAGCTGTGA >OriGene 5' read for NM_025135 unedited
ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTGTCCCTGGTAATTTATTGG TTCCTCCTCCTCCAGTGTTCAACGCTCCTCAGGGCTTAGGGTGGTCCCAGGTACCCAGGG GTCAGCCCACATTCACTAAGAAAAAGAAGACCATCCGTTTGTTCTGGAATGAAGTTCGGC CTTTTGACTGGCCATGTAAAAACAACCGACGCTGCAGAGAATTCCTGTGGTCAAAACTGG AACCCATTAAGGTGGACACTTCCAGACTGGAGCACCTGTTTGAGTCTAAATCCAAGGAAC TGTCTGTCTCAAAGAAAACTGCTGCAGATGGAAAAAGGCAAGAGATCATTGTTCTGGATT CCAAGAGGAGTAACGCCATCAATATTGGTCTGACGGTGCTGCCCCCTCCAAGGACGATTA AGATCGCCATTTTGAATTTTGATGAGTATGCCTTAAACAAAGAAGGAATCGAGAAAATTC TAACGATGATTCCCACCGATGAGGAGAAGCAGAAAATCCAGGAAGCTCAGCTGGCCAACC CTGAAATCCCCCTGNGCAGTGCAGAGCAGTTCCTCCTCACCCTGTCCTCCATCAGCGAGC TCTCTGCACGACTTCACCTCTGGGCATTCAAAATGGATTATGAAACTACAGAAAAGGAAG TAGCAGAACCACTCCTGGACCTGANAGAAGGAATAGACCAGTTGGAGAACATAAACCTTG GGCTNTATCCTGTCTACTCTCTTAGCCATTGGGAACTTTCTAAATGGAACTAATGCCANN AGCGTTTGAGTTAAGCTACCTCGAGAAGGTNNCAGAAGTCAAGACACAGTGCACAAGCAG TCGCTTCTCACCATGTGTGCACCATGGNTGGNTAGAAACTTCCAGAAGGCTCCGATCTGT CNTTCGAGATACGGGCCATCACCCAGTCANCCAAGGGTGACTTTGATCAACTCAGGAAAA TTNATGTCAAATGGAAAGAGATGCC >OriGene 3' read for NM_025135 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGCATTAAACTCTATT TATTTAGTATTTGAAACATGGTGTACATGTATGTATTTGTATAAACATTTGTTACATCTA AAATCCACAACAGGTAAACAATCTGTGCTTTCTTTTGTGTACAAGTTTGGGGTTTACATC TGGATATTTTGGTGTTGTGGAGACTCAGTCTGTGAAGCTAATCAGATTGCCTCATATTAC CATAATAACTGTGACAGAAGTGATTTGCTCCTTAAAGGGGCTGTTCCTTGCCCAGAAAAG GTGTCACACTTTTGAACTAATAAACCGGGTGTCACGGAATCAAGAGAAACACAGCTGACA CGATGGAGAAGGTATGTGCAGGGGACTCCTGGAGATCCAAGTCAATGCGTAGCAGGCAAC ACAAGCCATGGGGTGACGCTGGGAATTGAGCTCTCCCTTTTCAAACTGTTGGATGTGAAT ATCAAGTCTCCCCAACCCCACCTGGAGGGGTTTCATCCAGCAAGAGCTTGCCTTCTGCTC AGCACACTCCTGGGAGTAACCTATGAGTGTCACAGCTGCAACTCCGAGGTGCCAACCAAG CCCAGGGCTCNTGGCTTCTTCTGGGGTCAGGCCGCTCTTCAGGGTTCTTCGCAAAGATTT CCGGTTGGCCCNNGGATCGTTTCCTCTCCCTCGGCACCACTCGCTGACTGGGCACTTGGG TGGCTGACTTGACGATGCNGTCCATGATCTCATCAGCTGCATCATCTGTGACATTGGGCG AGTCATCAGTTCCCATAGTNCCAGAACTAGTGGATCCCTCGCTTTGCTCGCTGCGTGTGC GGACGCCANCGCGGGGNNTGCGTCCTCCACGGAGGGGACNAGTTTTCACACAGCCTTCAT GTNTCGTGCTCACCCCGGTCTCCCATAGCTAAACCTGCGGCNTGCTNGGGGCCCCGAAAC TGCGGAAACTGCCCATCGNGAAATCTCCTTTGGCCTATTCCTTTTGGGGTGCCGTTCTGT T |
| Restriction Sites | NotI-NotI |
| ACCN | NM_025135 |
| Insert Size | 2390 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_025135.1, NP_079411.1 |
| RefSeq Size | 5002 bp |
| RefSeq ORF | 1257 bp |
| Locus ID | 80206 |
| UniProt ID | Q2V2M9 |
| Domains | FH2 |
| Gene Summary | The protein encoded by this gene is a member of the diaphanous-related formins (DRF), and contains multiple domains, including GBD (GTPase-binding domain), DID (diaphanous inhibitory domain), FH1 (formin homology 1), FH2 (formin homology 2), and DAD (diaphanous auto-regulatory domain) domains. This protein is thought to play a role in actin filament polymerization in cardiomyocytes. Mutations in this gene have been associated with dilated cardiomyopathy (DCM), characterized by dilation of the ventricular chamber, leading to impairment of systolic pump function and subsequent heart failure. Increased levels of the protein encoded by this gene have been observed in individuals with hypertrophic cardiomyopathy (HCM). Alternative splicing results in multiple transcript variants encoding different isoforms. A muscle-specific isoform has been shown to possess a casein kinase 2 (CK2) phosphorylation site at the C-terminal end of the FH2 domain. Phosphorylation of this site alters its interaction with sequestosome 1 (SQSTM1), and targets this isoform to myofibrils, while other isoforms form cytoplasmic aggregates. [provided by RefSeq, Aug 2015] Transcript Variant: This variant (1) encodes isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221215 | FHOD3 (Myc-DDK-tagged)-Human formin homology 2 domain containing 3 (FHOD3) |
CNY 9848.00 |
|
| RC221215L3 | Lenti ORF clone of Human formin homology 2 domain containing 3 (FHOD3), Myc-DDK-tagged |
CNY 12248.00 |
|
| RC221215L4 | Lenti ORF clone of Human formin homology 2 domain containing 3 (FHOD3), mGFP tagged |
CNY 16250.00 |
|
| RG221215 | FHOD3 (tGFP-tagged) - Human formin homology 2 domain containing 3 (FHOD3) |
CNY 15770.00 |
|
| SC318619 | FHOD3 (untagged)-Human formin homology 2 domain containing 3 (FHOD3) |
CNY 27650.00 |
