NALP2 (NLRP2) (NM_017852) Human Untagged Clone
CAT＃: SC113899
NLRP2 (untagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1
CNY 7400.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLR19.9; NALP2; NBS1; PAN1; PYPAF2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_017852 edited
GAATTCGGCACGAGGCTGCAGCCCTCATCTCCGCCGGCGAGTAGGGCCAGGTGTTGGGAG CTCCCACGTGGGACAAGATGGTGTCTTCGGCGCAGATGGGCTTCAACCTGCAGGCTCTCC TGGAGCAGCTCAGCCAGGATGAGTTGAGCAAGTTCAAGTATCTGATCACGACCTTCTCCC TGGCACACGAGCTCCAGAAGATCCCCCACAAGGAGGTAGACAAGGCTGATGGGAAGCAAC TGGTAGAAATCCTCACCACCCATTGTGACAGCTACTGGGTGGAGATGGCGAGCCTCCAGG TCTTTGAAAAGATGCACCGAATGGATCTGTCTGAGAGAGCAAAGGATGAAGTCAGAGAAG CAGCTTTGAAATCCTTTAATAAAAGGAAACCTCTATCATTAGGGATAACACGGAAAGAAC GACCACCTCTAGACGTGGACGAAATGCTGGAGCGCTTCAAAACAGAAGCACAAGCGTTTA CAGAAACGAAAGGAAATGTCATCTGCCTGGGTAAAGAAGTCTTTAAAGGAAAAAAGCCAG ACAAAGACAATAGGTGCAGGTATATATTGAAGACGAAGTTCCGGGAGATGTGGAAGAGCT GGCCTGGAGATAGCAAAGAGGTCCAGGTTATGGCTGAGAGATACAAGATGCTGATCCCAT TCAGCAACCCCAGGGTGCTTCCCGGGCCCTTCTCATACACGGTGGTGCTGTATGGTCCTG CAGGCCTTGGGAAAACCACGCTGGCCCAGAAACTAATGCTAGACTGGGCAGAGGACAACC TCATCCACAAATTCAAATATGCGTTCTACCTCAGCTGCAGGGAGCTCAGCCGCCTGGGCC CGTGCAGTTTTGCAGAGCTGGTCTTCAGGGACTGGCCTGAATTGCAGGATGACATTCCAC ACATCCTAGCCCAAGCACGGAAAATCTTGTTCGTGATTGACGGCTTTGATGAGCTGGGAG CCGCACCTGGGGCGCTGATCGAGGACATCTGCGGGGACTGGGAGAAGAAGAAGCCGGTGC CCGTCCTCCTGGGGAGTTTGCTGAACAGGGTGATGTTACCCAAGGCCGCCCTGCTGGTCA CCACGCGGCCCAGGGCCCTGAGGGACCTCCGGATCCTGGCGGAGGAGCCGATCTACATAA GGGTGGAGGGCTTCCTGGAGGAGGACAGGAGGGCCTATTTCCTGAGACACTTTGGAGACG AGGACCAAGCCATGCGTGCCTTTGAGCTAATGAGGAGCAACGCGGCCCTGTTCCAGCTGG GCTCGGCCCCCGCGGTGTGCTGGATCGTGTGCACGACTCTGAAGCTGCAGATGGAGAAGG GGGAGGACCCGGTCCCCACCTGCCTCACCCGCACGGGGCTGTTCCTGCGTTTCCTCTGCA GCCGGTTCCCGCAGGGCGCACAGCTGCGGGGCGCGCTGCGGACGCTGAGCCTCCTGGCCG CGCAGGGCCTGTGGGCGCAGACGTCCGTGCTTCACCGAGAGGATCTGGAAAGGCTCGGGG TGCAGGAGTCCGACCTCCGTCTGTTCCTGGACGGAGACATCCTCCGCCAGGACAGAGTCT CCAAAGGCTGCTACTCCTTCATCCACCTCAGCTTCCAGCAGTTTCTCACTGCCCTGTTCT ACACCCTGGAGAAGGAGGAGGAAGAGGATAGGGACGGCCACACCTGGGACATTGGGGACG TACAGAAGCTGCTTTCCGGAGTAGAAAGACTCAGGAACCCCGACCTGATCCAAGCAGGCT ACTACTCCTTTGGCCTCGCTAACGAGAAGAGAGCCAAGGAGTTGGAGGCCACTTTTGGCT GCCGGATGTCACCGGACATCAAACAGGAATTGCTGCGATGCGACATAAGTTGTAAGGGTG GACATTCAACGGTGACAGACCTGCAGGAGCTCCTCGGCTGTCTGTACGAGTCTCAGGAGG AGGAGCTGGTGAAGGAGGTGATGGCTCAGTTCAAAGAAATATCCCTGCACTTAAATGCAG TAGACGTTGTGCCATCTTCATTCTGCGTCAAGCACTGTCGAAACCTGCAGAAAATGTCAC TGCAGGTAATAAAGGAGAATCTCCCGGAGAATGTCACTGCGTCTGAATCAGACGCCGAGG TTGAGAGATCCCAGGATGATCAGCACATGCTTCCTTTCTGGACGGACCTTTGTTCCATAT TTGGATCAAATAAGGATCTGATGGGTCTAGCAATCAATGATAGCTTTCTCAGTGCCTCCC TAGTAAGGATCCTGTGTGAACAAATAGCCTCTGACACCTGTCATCTCCAGAGAGTGGTGT TCAAAAACATTTCCCCAGCTGATGCTCATCGGAACCTCTGCCTAGCTCTTCGAGGTCACA AGACTGTAACGTATCTGACCCTTCAAGGCAATGACCAGGATGATATGTTTCCCGCATTGT GTGAGGTCTTGAGACATCCAGAATGTAACCTGCGATATCTCGGGTTGGTGTCTTGTTCCG CTACCACTCAGCAGTGGGCTGATCTCTCCTTGGCCCTTGAAGTCAACCAGTCCCTGACGT GCGTAAACCTCTCCGACAATGAGCTTCTGGATGAGGGTGCTAAGTTGCTGTACACAACTT TGAGACACCCCAAGTGCTTTCTGCAGAGGTTGTCGTTGGAAAACTGTCACCTTACAGAAG CCAATTGCAAGGACCTTGCTGCTGTGTTGGTTGTCAGCCGGGAGCTGACACACCTGTGCT TGGCCAAGAACCCCATTGGGAATACAGGGGTGAAGTTTCTGTGTGAGGGCTTGAGGTACC CCGAGTGTAAACTGCAGACCTTGGTGCTTTGGAACTGCGACATAACTAGCGATGGCTGCT GCGATCTCACAAAGCTTCTCCAAGAAAAATCAAGCCTGTTGTGTTTGGATCTGGGGCTGA ATCACATAGGAGTTAAGGGAATGAAGTTCCTGTGTGAGGCTTTGAGGAAACCACTGTGCA ACTTGAGATGTCTGTGGTTGTGGGGATGTTCCATCCCTCCGTTCAGTTGTGAAGACCTCT GCTCTGCCCTCAGCTGCAACCAGAGCCTCGTCACTCTGGACCTGGGTCAGAATCCCTTGG GGTCTAGTGGAGTGAAGATGCTGTTTGAAACCTTGACATGTTCCAGTGGCACCCTCCGGA CACTCAGGTTGAAAATAGATGACTTTAATGATGAACTCAATAAGCTGCTGGAAGAAATAG AAGAAAAAAACCCACAACTGATTATTGATACTGAGAAACATCATCCCTGGGCAGAAAGGC CTTCTTCTCATGACTTCATGATCTGAATCCCCCCGAGTCATTCATTCTCCATGAAGTCAT CGATTTTCCAGGTGTTGGTGAACTGCCTGTGACTCCTCTCCTCCCCGGCCCCTACCCCTC AGGGATAATGAGTTCATTGCTGGGCTAGATGTTTTAGCCATGATTCTGCCTCTGTTTTAT ACCTGCACACATCCTTATCTTTGTTACATATGAAATATCTGTATCACGGGTATATTGAGA GAAATAAAGGTGAGAGCATTCACAAATGAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_017852 unedited
TCGGTTTTGTATACGACTCCTATAGGCGGCCGCGNATTCGGCACGAGGCTGCAGCCCTCA TCTCCGCCGGCGAGTAGGGCCAGGTGTTGGGAGCTCCCACGTGGGACAAGATGGTGTCTT CGGCGCAGATGGGCTTCAACCTGCAGGCTCTCCTGGAGCAGCTCAGCCAGGATGAGTTGA GCAAGTTCAAGTATCTGATCACGACCTTCTCCCTGGCACACGAGCTCCAGAAGATCCCCC ACAAGGAGGTAGACAAGGCTGATGGGAAGCAACTGGTAGAAATCCTCACCACCCATTGTG ACAGCTACTGGGTGGAGATGGCGAGCCTCCAGGTCTTTGAAAAGATGCACCGAATGGATC TGTCTGAGAGAGCAAAGGATGAAGTCAGAGAAGCAGCTTTGAAATCCTTTAATAAAAGGA AACCTCTATCATTAGGGATAACACGGAAAGAACGACCACCTCTAGACGTGGACGAAATGC TGGAGCGCTTCAAAACAGAAGCACAAGCGTTTACAGAAACGAAAGGAAATGTCATCTGCC TGGGTAAAGAAGTCTTTAAAGGAAAAAAGCCAGACAAAGACAATAGGTGCAGGTATATAT TGAAGACGAAGTTCCGGGAGATGTGGAAGAGCTGGCCTGGAGATAGCAAAGAGGTCCAGG TTATGGCTGAGAGATACAAGATGCTGATCCCATTCACACCCCCCAGGGTGCTTCCCGGGC CCTTCTATACACGGTGGTGCTGTATGGTCCTGCNAGCCTTGGNGANACCACGCTGGCCCA GAACTATGCTAGACTGGGCAGAGGGACACCTCATCCACAATTCAAATATGCGTTCTACCT CAGCTGCAGGGAGCTCAGCCGCCTGGGCCCCGTGCAGTTTTGCCAGAGCTGGTCTTTCAG GNACTGCNNCTGAATTGCAGNATGACATTCACC >OriGene 3' read for NM_017852 unedited
TTGCTTTGGACCGCGGGCCGCAATCTAGGGTCGAGTTTTTTTTTTTTTTTTTTCATTTGT GAATGCTCTCACCTTTATTTCTCTCAATATACCCGTGATACAGATATTTCATATGTAACA AAGATAAGGATGTGTGCAGGTATAAAACAGAGGCAGAATCATGGCTAAAACATCTAGCCC AGCAATGAACTCATTATCCCTGAGGGGTAGGGGCCGGGGAGGAGAGGAGTCACAGGCAGT TCACCAACACCTGGAAAATCGATGACTTCATGGAGAATGAATGACTCGGGGGGATTCAGA TCATGAAGTCATGAGAAGAAGGCCTTTCTGCCCAGGGATGATGTTTCTCAGTATCAATAA TCAGTTGGGGGTTTTTTTCTTCTATTTCTTCCAGCAGCTTATTGAGTTCATCATTAAAGT CATCTATTTTCAACCTGAGTGTCCGGAGGGTGCCACTGGAACATGTCAAGGTTTCAAACA GCATCTTCACTCCACTAGACCCCAAGGGATTCTGACCCAGGTCCAGAGTGACGAGGCTCT GGTTGCAGCTGAGGGCAGAGCAGAGGTCTTCACAACTGAACGGAGGGATGGAACATCCCC ACAACCACAGACATCTCAAGTTGCACAGTGGTTTCCTCAAAGCCTCACACAGGAACTTCA TTCCCTTAACTCCTATGTGATTCAGCCCCAGATCCAAACACAACAGGCTTGATTTTTCTT GGAGAAGCTTTGTGAGATCGCAGCAGCCATCGCTAGTTATGTCGCAGTTCCAAAGCACCA AGGTCTGCAGTTTACACTCGGGTACCTCAAGCCCTCCACAGAAACTTCACCCCTGTATTN CAATGGGGNTNCTGGNCCAAAGCACAGTGTGNTCAGCTCCCGGCTGACAACCAACACAGC AGCAGGTCCTTGCAATGGNCTTCTGTANGGTGACAGNNTTTCAACGACAACCTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017852 |
| Insert Size | 3700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017852.1, NP_060322.1 |
| RefSeq Size | 3531 bp |
| RefSeq ORF | 3189 bp |
| Locus ID | 55655 |
| UniProt ID | Q9NX02 |
| Domains | LRR, LRR_RI |
| Gene Summary | This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016] Transcript Variant: This variant (1) encodes the longest isoform (1). Both variants 1 and 2 encode the same isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201357 | NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1 |
CNY 7392.00 |
|
| RC201357L1 | Lenti ORF clone of Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, Myc-DDK-tagged |
CNY 9792.00 |
|
| RC201357L2 | Lenti ORF clone of Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, mGFP tagged |
CNY 9792.00 |
|
| RC201357L3 | Lenti ORF clone of Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, Myc-DDK-tagged |
CNY 11020.00 |
|
| RC201357L4 | Lenti ORF clone of Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, mGFP tagged |
CNY 9792.00 |
|
| RG201357 | NLRP2 (tGFP-tagged) - Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1 |
CNY 10070.00 |
