MARK2 (NM_017490) Human Untagged Clone
CAT＃: SC114124
MARK2 (untagged)-Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1
CNY 5464.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EMK-1; EMK1; PAR-1; Par-1b; Par1b |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_017490 edited
ATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTAC CGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATC CTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGC CTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTT AAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGT GGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGA GCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCAT AGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGAC TTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCC CCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTG TGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAG AACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATG TCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGC ACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTA AAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTG TCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAG GTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATC ACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCAC AAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCTGGT CCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAAT AAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCT GCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAACAGC GTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTC GGCCAGGCCTCCATCCAGAATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCC TCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCC CGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAG CAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGG GGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCT TTCAGGTTTGCCAGAAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAA GAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACTACGAGC TCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGC CAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAG GACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTT CGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCC AACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGA CGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGT CTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTGTG GGGGGTGGGAGATTGTTCTCCAGCCCCCCACATTCACCCCTGCCCAGAGATTCCCCCTTC TCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCT CGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAG AAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAA CAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTG CCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACT AGGTGTCCTTCTATAATATTATGGGGTGGAGGGGGGTGGTATGGAGCAAGGGGCAAGTTG GGAAGACAACCTGTAGGGCCTGCGGGGTCTATTGGGAACCAAGCTGGAGTGCAGTGGCAC AATCTTGGCTCACTGCAATCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTC CCGAGTTGTTGGGATTCCAGGCATGCATGACCAGGCTCAGCTAATTTTTGTTTTTTTGGT AGAGACGGGGTTTCACCATATTGGCCAGGCTGGTCTCCAACTCCTAATCTCAGGTGATCT ACCCACCTTGGCCTCCCAAATTGCTGGGATTACAGGCGTGAACCACTGCTCCCTTCCCTG TCCTTCTGATTTTAAAATAACTATACCAGCGGGAGGACGTCCAGACACAGCA >OriGene 5' read for NM_017490 unedited
GTAATACGACTTTCTATAGGGCGGCCGCGAATTCGGCACGAGGCTGAACGAGAGGGACAC GGAGCAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCG GGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCT CAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGG GAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAA ACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATT TGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGA GGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATT CCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCATAGAGACTT AAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTT CAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGC TGCCCCAGAACTCTTCCAGGGCANAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCT ANGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCCTCA AGAGCTGCGGGAACGGGTACTGANGGGGAAAATACCGTATTCCATTCTACATGTCCACGG ACTGTGGAAACCTGCTTAAGAAATTCTCATTNCTAATCCCAGCAGAGAGCACTTANAGCN ATCATGAAGATCGATNATGAATGGGGTNACGAANATGAGAACTAAGNCCTACGTGGACCA CTNCTGACTCAGGACCC >OriGene 3' read for NM_017490 unedited
GCCTATGGACCGCGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTCTTTTTGGTA ATAAAAAATTTCTTGGTTTAGGCGAAATACTCTGTGCAACCGCAGTACCGAGGGGGAGCC CTGCCCCCCCATCCACCCTCCCCTTCCTTTGCCTCCAGTAGGGGAGAGGAGAAGGGGGAA TCTCTGGGCAGGGGTGAATGTGGGGGNCTNNNNAANNNNNCCCCNCCCCCCNCCCNNCCC CCCCCCNCCNNCNCCCCCTTTCCCCCCCCCNCCNCCCCCCCCCCCCCCCCCNNCCCCCCC CCCCCNCCCCCNCCCCCCCCNNNCNCCCCCCCCCCCCCCCCCCCNCCCCCCCNNNCCCCC NCCCCCCCCNCCCCCCCCCCNCNCCCCCCCTCCCCCCCNNCCCCCCCCCNCCCCCCCCCN CCCCCCCCNNCCCCCCCCCCCCCCCCCCNCCCCCNCNNCCCCCCCCCCCNCCCCNCCCCC CCNNCCCCCCCCNCCCCCCCCCCNNNCCCCCCCNCCCCCCCCCCCCCCCCCNNCCCCCCN CNCCCNCCCCCCCCCCCCCCCCCCNCNNNCCCCCCCCCCNNCCNCCCCNCCCNNCCCCNN NNCCCCCNNCCCNNCCCCNNCCCCCNCCCCCCCCNCCCCTCNNCCCCCNCCCCCCNCCCC CNCCCCCTCCCCCCCCNTCCCCCCCCTCCCCCTCTTCTTCTCCCTCNCTGTCTTCCTTCC CTCCCCCTTCTTTTCCCCCCNCTTTCCCCTTTTCCTCCCCCCCTCCTCTTTTNTCCCCCC TTTTCTTGTTTTTCCCTTCCCCCCTTTCTCCTCTCTTTTTCCCTTTTTTTCCCTCTCCCT TTTCCCCCTCCCTTTCTCCCTTCTCCTTTCTCTCCGTCCTTCTTTCTTCTTTTTTCTTTC TCTTTTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017490 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017490.1, NP_059672.1 |
| RefSeq Size | 2946 bp |
| RefSeq ORF | 2238 bp |
| Locus ID | 2011 |
| UniProt ID | Q7KZI7 |
| Domains | UBA, pkinase, KA1 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] Transcript Variant: This variant (1) represents use of an alternate promoter and 5' UTR, uses a downstream start codon, lacks an in-frame exon, and uses an alternate in-frame splice site, compared to variant 4. The resulting isoform (a) has a shorter N-terminus and lacks an internal segment and 1 internal residue, compared to isoform d. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213764 | MARK2 (Myc-DDK-tagged)-Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1 |
CNY 5456.00 |
|
| RC213764L1 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, Myc-DDK-tagged |
CNY 7856.00 |
|
| RC213764L2 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, mGFP tagged |
CNY 9690.00 |
|
| RC213764L3 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, Myc-DDK-tagged |
CNY 9690.00 |
|
| RC213764L4 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, mGFP tagged |
CNY 9690.00 |
|
| RG213764 | MARK2 (tGFP-tagged) - Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1 |
CNY 7056.00 |
|
| SC323417 | MARK2 (untagged)-Kinase deficient mutant (K49M) of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1 |
CNY 5464.00 |
