CNAP1 (NCAPD2) (NM_014865) Human Untagged Clone
CAT＃: SC114817
NCAPD2 (untagged)-Human non-SMC condensin I complex, subunit D2 (NCAPD2)
CNY 10960.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAP-D2; CNAP1; hCAP-D2; MCPH21 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114817 sequence for NM_014865 edited (data generated by NextGen Sequencing)
ATGGCTCCCCAAATGTATGAGTTCCATCTGCCATTATCCCCAGAGGAGTTGTTGAAAAGT GGAGGGGTGAATCAGTATGTTGTGCAAGAGGTACTGTCCATCAAACATCTTCCACCACAG CTTAGAGCTTTTCAGGCTGCCTTTCGAGCTCAGGGGCCCCTGGCTATGCTGCAGCACTTT GATACTATCTACAGCATTTTGCATCACTTTCGAAGTATAGATCCTGGCCTCAAAGAAGAT ACTCTGCAATTCCTGATAAAAGTGGTATCCCGCCACTCCCAGGAGCTTCCAGCTATCCTG GATGATACAACTTTGAGTGGATCAGATAGAAACGCCCATCTAAATGCCCTCAAAATGAAC TGTTATGCTCTGATACGTCTCCTGGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTT GTGGACCTGGACCTTGGTGGGAAGGGTAAGAAAGCTCGGACCAAGGCAGCCCATGGCTTT GACTGGGAAGAAGAGAGGCAACCAATTCTTCAGCTTTTAACACAGCTACTTCAGTTGGAC ATCCGTCACCTGTGGAACCACTCAATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGC TGTTGCTACCGCCTTCTGGAGAATCCCACCATTAATCACCAGAAGAACCGCCCCACTCGG GAAGCCATAACACACCTGCTTGGTGTAGCCTTGACCCGTTATAACCATATGCTCAGTGCT ACAGTGAAGATCATCCAGATGCTGCAGCACTTTGAACACCTGGCACCTGTACTGGTTGCA GCCGTGAGTCTATGGGCAACTGACTATGGAATGAAGAGCATAGTGGGAGAGATTGTAAGA GAGATTGGACAAAAGTGTCCCCAAGAGCTGAGTCGAGACCCTTCAGGGACAAAGGGCTTT GCAGCATTCCTGACAGAACTAGCAGAACGTGTCCCAGCTATCCTGATGTCCAGCATGTGC ATTTTGCTAGATCACCTGGATGGAGAAAATTACATGATGCGTAATGCTGTGCTGGCAGCC ATGGCGGAGATGGTGCTGCAGGTTCTCAGTGGCGATCAACTGGAAGCAGCAGCCCGAGAC ACCAGAGACCAGTTCTTGGATACTTTACAAGCCCATGGCCATGATGTCAACTCCNNTGTG CGGAGCCGTGTTTTGCAGCTCTTCACCCGAATTGTCCAGCAGAAGGCTCTCCCCCTGACA CGTTTCCAGGCAGTGGTGGCTTTAGCTGTGGGACGTCTGGCAGACAAGTCAGTGCTAGTA TGTAAAAATGCCATCCAGCTGCTGGCCAGTTTTCTAGCCAATAATCCTTTCTCCTGCAAG CTTAGTGATGCTGACCTTGCCGGACCACTGCAGAAGGAGACCCAGAAATTACAAGAGATG AGGGCCCAGAGGCGAACTGCAGCAGCTTCTGCAGTGCTGGACCCAGAGGAGGAGTGGGAA GCCATGCTGCCAGAGTTGAAGTCTACCCTGCAGCAGCTTCTACAGCTTCCCCAGGGAGAG GAGGAGATTCCTGAGCAAATTGCCAATACAGAGACAACTGAAGATGTGAAAGGACGCATC TATCAACTGCTTGCCAAAGCTAGTTACAAAAAGGCCATCATTCTCACTCGAGAAGCCACA GGCCACTTCCAGGAGTCCGAACCCTTCAGTCATATAGACCCAGAGGAGTCAGAGGAGACC AGGCTCTTGAATATCTTAGGACTTATCTTCAAAGGCCCAGCAGCTTCCACACAAGAAAAG AATCCCCGGGAGTCTACAGGAAACATGGTCACAGGACAGACTGTCTGTAAAAATAAACCC AATATGTCGGATCCTGAGGAATCCAGGGGAAATGATGAACTAGTGAAGCAGGAGATGCTG GTACAGTATCTGCAGGATGCCTACAGCTTCTCCCGGAAGATTACAGAGGCCATTGGCATC ATCAGCAAGATGATGTATGAAAACACAACTACAGTGGTGCAGGAGGTGATTGAATTCTTT GTGATGGTCTTCCAATTTGGGGTACCCCAGGCCCTGTTTGGGGTGCGCCGTATGCTGCCT CTCATCTGGTCTAAGGAGCCTGGTGTCCGGGAAGCCGTGCTTAATGCCTACCGCCAACTC TACCTCAACCCCAAAGGGGACTCTGCCAGAGCCAAGGCCCAGGCTTTGATTCAGAATCTC TCTCTGCTGCTAGTGGATGCCTCGGTTGGGACCATTCAGTGTCTTGAGGAAATTCTCTGT GAGTTTGTGCAGAAGGATGAGTTGAAACCAGCAGTGACCCAGCTGCTGTGGGAGCGGGCC ACCGAGAAGGTCGCCTGCTGTCCTCTGGAGCGCTGTTCCTCTGTCATGCTTCTTGGCATG ATGGCACGAGGAAAGCCAGAAATTGTGGGAAGCAATTTAGACACACTGGTGAGCATAGGG CTGGATGAGAAGTTTCCACAGGACTACAGGCTGGCCCAGCAGGTGTGCCATGCCATTGCC AACATCTCGGACAGGAGAAAGCCTTCTCTGGGCAAACGTCACCCCCCCTTCCGGCTGCCT CAGGAACACAGGTTGTTTGAGCGACTGCGGGAGACAGTCACAAAAGGCTTTGTCCACCCA GACCCACTCTGGATCCCATTCAAAGAGGTGGCAGTGACCCTCATTTACCAACTGGCAGAG GGCCCCGAAGTGATCTGTGCCCAGATATTGCAGGGCTGTGCAAAACAGGCCCTGGAGAAG CTAGAAGAGAAGAGAACCAGTCAGGAGGACCCGAAGGAGTCCCCCGCAATGCTCCCCACT TTCCTGTTGATGAACCTGCTGTCCCTGGCTGGGGATGTGGCTCTGCAGCAGCTGGTCCAC TTGGAGCAGGCAGTGAGTGGAGAGCTCTGCCGGCGCCGAGTTCTCCGGGAAGAACAGGAG CACAAGACCAAAGATCCCAAGGAGAAGAATACGAGCTCTGAGACCACCATGGAGGAGGAG CTGGGGCTGGTTGGGGCAACAGCAGATGACACAGAGGCAGAACTAATCCGTGGCATCTGC GAGATGGAACTGTTGGATGGCAAACAGACACTGGCTGCCTTTGTTCCACTCTTGCTTAAA GTCTGTAACAACCCAGGCCTCTATAGCAACCCAGACCTCTCTGCAGCTGCTTCACTTGCC CTTGGCAAGTTCTGCATGATCAGTGCCACTTTCTGCGACTCCCAGCTTCGTCTTCTGTTC ACCATGCTGGAAAAGTCTCCACTTCCCATTGTCCGGTCTAACCTCATGGTTGCCACTGGG GATCTGGCCATCCGCTTTCCCAATCTGGTGGACCCCTGGACTCCTCATCTGTATGCTCGT CTCCGGGACCCTGCTCAGCAAGTGCGGAAAACAGCGGGGCTGGTGATGACCCACCTGATC CTCAAGGACATGGTGAAGGTGAAGGGGCAGGTCAGCGAGATGGCGGTGCTGCTCATCGAC CCCGAGCCTCAGATTGCTGCCCTGGCCAAGAACTTCTTCAATGAGCTCTCCCACAAGGGC AACGCAATCTATAATCTCCTTCCAGATATCATCAGCCGCCTGTCAGACCCCGAGCTGGGG GTGGAGGAAGAGCCTTTCCACACCATCATGAAACAGCTCCTCTCCTACATCACCAAGGAC AAGCAGACAGAGAGCCTGGTGGAAAAGCTGTGTCAGCGGTTCCGCACATCCCGAACTGAG CGGCAGCAGCGAGACCTGGCCTACTGTGTGTCACAGCTGCCCCTCACAGAGCGAGGCCTC CGTAAGATGCTTGACAATTTTGACTGTTTTGGAGACAAACTGTCAGATGAGTCCATCTTC AGTGCTTTTTTGTCAGTTGTAGGCAAGCTGCGACGTGGGGCCAAGCCTGAGGGCAAGGCT ATAATAGATGAATTTGAGCAGAAGCTTCGGGCCTGTCATACCAGAGGTTTGGATGGAATC AAGGAGCTTGAGATTGGCCAAGCAGGTAGCCAGAGAGCGCCATCAGCCAAGAAACCATCC ACTGGTTCTAGGTACCAGCCTCTGGCTTCTACAGCCTCAGACAATGACTTTGTCACACCA GAGCCCCGCCGTACTACCCGTCGGCATCCAAACACCCAGCAGCGAGCTTCCAAAAAGAAA CCCAAAGTTGTCTTCTCAAGTGATGAGTCCAGTGAGGAAGATCTTTCAGCAGAGATGACA GAAGACGAGACACCCAAGAAAACAACTCCCATTCTCAGAGCATCGGCTCGCAGGCACAGA TCCTAG Clone variation with respect to NM_014865.3 1135 t=>n;1136 t=>n >OriGene 5' read for NM_014865 unedited
NGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCNCGCGATTCGGCACGAGGCCGCG GGTGAGATCCCCAGCCCTGTGAGCCTGTAGGAGTAGAATGGCTCCCCAAATGTATGAGTT CCATCTGCCATTATCCCCAGAGGAGTTGTTGAAAAGTGGAGGGGTGAATCAGTATGTTGT GCAAGAGGTACTGTCCATCAAACATCTTCCACCACAGCTTAGAGCTTTTCAGGCTGCCTT TCGAGCTCAGGGGCCCCTGGCTATGCTGCAGCACTTTGATACTATCTACAGCATTTTGCA TCACTTTCGAAGTATAGATCCTGGCCTCAAAGAAGATACTCTGCAATTCCTGATAAAAGT GGTATCCCGCCACTCCCAGGAGCTTCCAGCTATCCTGGATGATACAACTTTGAGTGGATC AGATAGAAACGCCCATCTAAATGCCCTCAAAATGAACTGTTATGCTCTGATACGTCTCCT GGAATCCTTTGAGACCATGGCCAGCCAGACAAACCTTGTGGACCTGGACCTTGGTGGGAA GGGTAAGAAAGCTCGGACCAAGGCAGCCCATGGCTTTGACTGGGAAGAAGAGAGGCAACC AATTCTTCAGCTTTTAACACAGCTACTTCAGTTGGACATCCGTCACCTGTGGAACCACTC AATAATTGAAGAAGAATTTGTCAGTTTGGTTACTGGCTGTTGCTACCGCCTTCTGGAGAA TCCCACCATTAATCACCAGAAGAACCGCCCCACTCGGGAAGCCATAACACACCTGCTTGG TGTAGCCTTGACCCGTTTAACCATATGCTCAGTGCTACAGTGAAGATCATCCAGATGCTG CAGCACTTTGAACACCCTGCACCTGTACTGGTTGCAGCCGTGAGTCTATGGGCACTGACT ATGAATGAAGACATATC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014865 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014865.1, NP_055680.1 |
| RefSeq Size | 5547 bp |
| RefSeq ORF | 4806 bp |
| Locus ID | 9918 |
| UniProt ID | Q15021 |
| Domains | Cnd1 |
| Gene Summary | Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain (PubMed:11136719). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206994 | NCAPD2 (Myc-DDK-tagged)-Human non-SMC condensin I complex, subunit D2 (NCAPD2) |
CNY 9584.00 |
|
| RC206994L3 | Lenti-ORF clone of NCAPD2 (Myc-DDK-tagged)-Human non-SMC condensin I complex, subunit D2 (NCAPD2) |
CNY 15870.00 |
|
| RC206994L4 | Lenti-ORF clone of NCAPD2 (mGFP-tagged)-Human non-SMC condensin I complex, subunit D2 (NCAPD2) |
CNY 15870.00 |
|
| RG206994 | NCAPD2 (tGFP-tagged) - Human non-SMC condensin I complex, subunit D2 (NCAPD2) |
CNY 15390.00 |
