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SLCO2B1 (NM_007256) Human Untagged Clone
CAT＃: SC115618
SLCO2B1 (untagged)-Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1
CNY 7,800.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OATP-B; OATP2B1; OATPB; SLC21A9 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115618 sequence for NM_007256 edited (data generated by NextGen Sequencing)
ATGGGACCCAGGATAGGGCCAGCGGGTGAGGTACCCCAGGTACCAGACAAGGAAACCAAA GCCACAATGGGCACAGAAAACACACCTGGAGGCAAAGCCAGCCCAGACCCTCAGGACGTG CGGCCAAGTGTGTTCCATAACATCAAGCTGTTCGTTCTGTGCCACAGCCTGCTGCAGCTG GCGCAGCTCATGATCTCCGGCTACCTAAAGAGCTCCATCTCCACAGTGGAGAAGCGCTTC GGCCTCTCCAGCCAGACGTCGGGGCTGCTGGCCTCCTTCAACGAGGTGGGGAACACAGCC TTGATTGTGTTTGTGAGCTATTTTGGCAGCCGGGTGCACCGACCCCGAATGATTGGCTAT GGGGCTATCCTTGTGGCCCTGGCGGGCCTGCTCATGACTCTCCCGCACTTCATCTCGGAG CCATACCGCTACGACAACACCAGCCCTGAGGATATGCCACAGGACTTCAAGGCTTCCCTG TGCCTGCCCACAACCTCGGCCCCAGCCTCGGCCCCCTCCAATGGCAACTGCTCAAGCTAC ACAGAAACCCAGCATCTGAGTGTGGTGGGGATCATGTTCGTGGCACAGACCCTGCTGGGC GTGGGCGGGGTGCCCATTCAGCCCTTTGGCATCTCCTACATCGATGACTTTGCCCACAAC AGCAACTCGCCCCTCTACCTCGGGATCCTGTTTGCAGTGACCATGATGGGGCCAGGCCTG GCCTTTGGGCTGGGCAGCCTCATGCTGCGCCTTTATGTGGACATTAACCAGATGCCAGAA GGTGGTATCAGCCTGACCATAAAGGACCCCCGATGGGTGGGTGCCTGGTGGCTGGGTTTC CTCATCGCTGCCGGTGCAGTGGCCCTGGCTGCCATCCCCTACTTCTTCTTCCCCAAGGAA ATGCCCAAGGAAAAACGTGAGCTTCAGTTTCGGCGAAAGGTCTTAGCAGTCACAGACTCA CCTGCCAGGAAGGGCAAGGACTCTCCCTCTAAGCAGAGCCCTGGGGAGTCCACGAAGAAG CAGGATGGCCTAGTCCAGATTGCACCAAACCTGACTGTGATCCAGTTCATTAAAGTCTTC CCCAGGGTGCTGCTGCAGACCCTACGCCACCCCATCTTCCTGCTGGTGGTCCTGTCCCAG GTATGCTTGTCATCCATGGCTGCGGGCATGGCCACCTTCCTGCCCAAGTTCCTGGAGCGC CAGTTTTCCATCACAGCCTCCTACGCCAACCTGCTCATCGGCTGCCTCTCCTTCCCTTCG GTCATCGTGGGCATCGTGGTGGGTGGCGTCCTGGTCAAGCGGCTCCACCTGGGCCCTGTG GGATGCGGTGCCCTTTGCCTGCTGGGGATGCTGCTGTGCCTCTTCTTCAGCCTGCCGCTC TTCTTTATCGGCTGCTCCAGCCACCAGATTGCGGGCATCACACACCAGACCAGTGCCCAC CCTGGGCTGGAGCTGTCTCCAAGCTGCATGGAGGCCTGCTCCTGCCCATTGGACGGCTTT AACCCTGTCTGCGACCCCAGCACTCGTGTGGAATACATCACACCCTGCCACGCAGGCTGC TCAAGCTGGGTGGTCCAGGATGCTCTGGACAACAGCCAGGTTTTCTACACCAACTGCAGC TGCGTGGTGGAGGGCAACCCCGTGCTGGCAGGATCCTGCGACTCAACGTGCAGCCATCTG GTGGTGCCCTTCCTGCTCCTGGTCAGCCTGGGCTCGGCCCTGGCCTGTCTCACCCACACA CCCTCCTTCATGCTCATCCTAAGAGGAGTGAAGAAAGAAGACAAGACTTTGGCTGTGGGC ATCCAGTTCATGTTCCTGAGGATTTTGGCCTGGATGCCCAGCCCCGTGATCCACGGCAGC GCCATCGACACCACCTGTGTGCACTGGGCCCTGAGCTGTGGGCGTCGAGCTGTCTGTCGC TACTACAATAATGACCTGCTCCGAAACCGGTTCATCGGCCTCCAGTTCTTCTTCAAAACA GGTTCTGTGATCTGCTTCGCCTTAGTTTTGGCTGTCCTGAGGCAGCAGGACAAAGAGGCA AGGACCAAAGAGAGCAGATCCAGCCCTGCCGTAGAGCAGCAATTGCTAGTGTCGGGGCCA GGGAAGAAGCCAGAGGATTCCCGAGTGTGA Clone variation with respect to NM_007256.4 >OriGene 5' read for NM_007256 unedited
GGCGGCCCGCGAATTCGCACGAGGGNACAGNAAGGGAGCAAGTGGACCCAGGGNAGACAA ACACTTGGAGATACTTGGGGCTGAGTTTGAGCAAGACTCCCTAACCTGTGTCTGGACAAG TCTGATGTCCTGTGTGGCCCAAGAAGAACTGACCCCGTGTCTGGAGCTCCCACCGTTATT GCATCCCTGCTGTGGCTCACCTGCTGCTGTCTCCAGGAGCCCCTGAGAAGATTTGCCTCC TCTCCCCTGCTAAGCTCCAGGTCCTGAGATTGAATTAGGGGCTGGAGCTCACTGCACTCC AGCAGTCATGGGACCCAGGATAGGGCCAGCGGGTGAGGTACCCCAGGTACCAGACAAGGA AACCAAAGCCACAATGGGCACAGAAAACACACCTGGAGGCAAAGCCAGCCCAGACCCTCA GGACGTGCGGCCAAGTGTGTTCCATAACATCAAGCTGTTCGTTCTGTGCCACAGCCTGCT GCAGCTGGCGCAGCTCATGATCTCCGGCTACCTAAAGAGCTCCATCTCCACAGTGGAGAA GCGCTTCGGCCTCTCCAGCCAGACGTCGGGGCTGCTGGCCTCCTTCAACGAGGTGGGGAA CACAGCCTTGATTGTGTTTGTGAGCTATTTTGGCAGCCGGGTGCACCGACCCCGAATGAT TGGCTATGGGGCTATCCTTGTGGCCCTGGCGGGCCTGCTCATGACTCTCCCGCACTTTCA TCTCGAGCCATACCGCTACGACAACACCAGCCCCTGAGATATGCCACAGGACTTCAGGGC TTCCCTGTGCCTGCCCACNAACCTCGNCCCAGCCNTCGNNCCNCTNCATTGGNCACTGCT CAAGCTCACANGAACCCCACATCTGANTGTGGTGGGGGATCATGTTCGTGGCACAGACCC TGCTGGNNCGTGGCCGGGGTGCCATTTCAGCCTTTTGCTT >OriGene 3' read for NM_007256 unedited
CCCCGAAATACTATGTACCGCGCCGCTTTCNANGATCGNATTTTTTTTTTTTTTTTTTTT TATGCAAAAACAAATTTAATAATAAGCTGTATCTATAATTCCAGACTTTTTTTCCCTGCA AAACCTGGGAAACAAGAGGGATGAAGGAATATAAACATCCTAAAAGCCTCATATTGTTGA AGGAGACTTTGAAATTCTTGGCGTTGATAGATACATGCTCAGATATTTATTAAACATTTA CAGATACCAACCAGCAAAATAAAAAGGGAATTGGAACTTCTGTACCTCCCTTTTCTTTTA TCATGTGGGAAAGTCTCAAAGCCCTGGCACTGGGAGCTGCTCAGAAGGCAAGGGCCACAT GTGCCCCCAGCTTCCCCCCACCCCCAGCACAGGGCCAGACAAGCCACTGCTGATGGCTCC CTGTCTGCTGCCTCCCGAGCAGTAGGTCCCAGCGAGGTGGGGTGGTAATAGGTTGGGCTG GGAGCAGATTAGCAAACCCTCTCCTCCCCGCAAGGAAATAACCAGGCCAGATAAGACTAG CCATAAAACAAAACAAGGGCTGATGTAGAAAAGGATTGGATCATAAGACACGAGCAAGCC ATAGCATCACTCATTACACAGAGCTGAGCTTTACTGCTCCCAGCACTACAGTCCTGGGCC TGACACCAGCCCCAGCATCGGAGAACCAGGTGCCACCCCCAAAAAACAGTGTCCCAGAAC TAAACATTATCCACACTGCCCCCAGTGACACAAACCCCAGCCCCCCAGAGAAAATAAAGA AATTAGGATCCCTATCACCAAAGTCACAGGGACTTTGGTGGCCCCTGGTACATGTGTGAA ATCTTGGCCAATGTGTAGAATCCATGACTGCGCGCTGGAGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007256 |
| Insert Size | 4130 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007256.2, NP_009187.1 |
| RefSeq Size | 4108 bp |
| RefSeq ORF | 2130 bp |
| Locus ID | 11309 |
| UniProt ID | O94956 |
| Domains | OATP_N, OATP_C |
| Protein Families | Transmembrane |
| Gene Summary | This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Role of OATP transporters in steroid uptake by prostate cancer cells in vivo
,Green, SM;Kaipainen, A;Bullock, K;Zhang, A;Lucas, JM;Matson, C;Banks, WA;Mostaghel, EA;,
Prostate Cancer Prostatic Dis.
,PubMed ID 27645128
[SLCO2B1]
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Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer
,Wang, X;Harshman, LC;Xie, W;Nakabayashi, M;Qu, F;Pomerantz, MM;Lee, GM;Kantoff, PW;,
J. Clin. Oncol.
,PubMed ID 26668348
[SLCO2B1]
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Interaction of Macrolide Antibiotics with Intestinally Expressed Human and Rat Organic Anion Transporting Polypeptides
,Tian Lan, Anuradha Rao, Jamie Haywood, Charles B. Davis, Chao Han, Eric Garver, and Paul A. Dawson,
Drug Metab. Dispos., Sep 2009; 10.1124/dmd.109.028522
[SLCO2B1]
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Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters
,Simone Leuthold, Bruno Hagenbuch, Nilufar Mohebbi, Carsten A Wagner, Peter J. Meier, and Bruno Stieger,
Am J Physiol Cell Physiol, Jan 2009; 10.1152/ajpcell.00436.2008.
[SLCO2B1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207759 | SLCO2B1 (Myc-DDK-tagged)-Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1 |
CNY 7,792.00 |
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| RC207759L1 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1, Myc-DDK-tagged |
CNY 10,192.00 |
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| RC207759L2 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1, mGFP tagged |
CNY 10,192.00 |
|
| RC207759L3 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1, Myc-DDK-tagged |
CNY 10,192.00 |
|
| RC207759L4 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1, mGFP tagged |
CNY 10,192.00 |
|
| RG207759 | SLCO2B1 (tGFP-tagged) - Human solute carrier organic anion transporter family, member 2B1 (SLCO2B1), transcript variant 1 |
CNY 9,392.00 |
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