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SIAH1 (NM_003031) Human Untagged Clone
CAT＃: SC118259
SIAH1 (untagged)-Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1
CNY 2,400.00
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BURHAS; SIAH1A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118259 sequence for NM_003031 edited (data generated by NextGen Sequencing)
ATGAGCCGTCAGACTGCTACAGCATTACCTACCGGTACCTCGAAGTGTCCACCATCCCAG AGGGTGCCTGCCCTGACTGGCACAACTGCATCCAACAATGACTTGGCGAGTCTTTTTGAG TGTCCAGTCTGCTTTGACTATGTGTTACCGCCCATTCTTCAATGTCAGAGTGGCCATCTT GTTTGTAGCAACTGTCGCCCAAAGCTCACATGTTGTCCAACTTGCCGGGGCCCTTTGGGA TCCATTCGCAACTTGGCTATGGAGAAAGTGGCTAATTCAGTACTTTTCCCCTGTAAATAT GCGTCTTCTGGATGTGAAATAACTCTGCCACACACAGAAAAAGCAGACCATGAAGAGCTC TGTGAGTTTAGGCCTTATTCCTGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGGCTCT CTGGATGCTGTAATGCCCCATCTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGA GAGGATATAGTTTTTCTTGCTACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATG ATGCAGTCCTGTTTTGGCTTTCACTTCATGTTAGTCTTAGAGAAACAGGAAAAATACGAT GGTCACCAGCAGTTCTTCGCAATCGTACAGCTGATAGGAACACGCAAGCAAGCTGAAAAT TTTGCTTACCGACTTGAGCTAAATGGTCATAGGCGACGATTGACTTGGGAAGCGACTCCT CGATCTATTCATGAAGGAATTGCAACAGCCATTATGAATAGCGACTGTCTAGTCTTTGAC ACCAGCATTGCACAGCTTTTTGCAGAAAATGGCAATTTAGGCATCAATGTAACTATTTCC ATGTGTTGA Clone variation with respect to NM_003031.3 >OriGene 5' read for NM_003031 unedited
GGTCGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCCGGGGCGGC CGTTGCGGGGCGCGCTCTCGAGAGGCGGCGGCGGCCCAGGGTGTCCCGTCGGTCTCGGCG CCGGGAAGAGGCGGTGGCGCTGCCCGCGGTGGCGGGGGTTGGCGACGGAGCGCGTTGGTG CCAGGACCGGGGTCCGAGGCGCGCTCTCCGCCCACAGAAATGAGCCGTCAGACTGCTACA GCATTACCTACCGGTACCTCGAAGTGTCCACCATCCCAGAGGGTGCCTGCCCTGACTGGC ACAACTGCATCCAACAATGACTTGGCGAGTCTTTTTGAGTGTCCAGTCTGCTTTGACTAT GTGTTACCGCCCATTCTTCAATGTCAGAGTGGCCATCTTGTTTGTAGCAACTGTCGCCCA AAGCTCACATGTTGTCCAACTTGCCGGGGCCCTTTGGGATCCATTCGCAACTTGGCTATG GAGAAAGTGGCTAATTCAGTACTTTTCCCCTGTAAATATGCGTCTTCTGGATGTGAAATA ACTCTGCCACACACAGAAAAAGCAGACCATGAAGAGCTCTGTGAGTTTAGGCCTTATTCC TGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGGCTCTCTGGATGCTGTAATGCCCCAT CTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGAGAGGATATAGTTTTTCTTGCT ACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATGATGCAGTCCTGTTTTGGCTTT CACTTCATGTTAGTCTTAGAGAAACAGGANAAATACGATGGTCACCAGCAGTTCTTCGCA ATCGTACAGCTGATAGGAACCACGCAGCAGCTGAAAATTTGCTTACCGACTGAGCTAAAT GTCAT >OriGene 3' read for NM_003031 unedited
CCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTAATTTGCCAGATATTCTTTTAATG AGAATTATAAAAGACCAAAAACATTTTTTGCAAACTGCCTTTTTAAACAAATGATTTGCT TTTAATTACAAATACTGTGCATGACGATGCCTTCTTCTGCAAAACCAATAAATACAAGAA CAAATTTTAAAATATGTGATTTGTCCAAGATATCTGAAAAAGGAAACAAAAGCCTGATTT GCAGTATTTATAAAAATCAATTTATTCTCTAACCTTTCAAAGATTAAGCTCAAAGGTGTG ACTCATCTGTAGAAGACAGAAAGAGAGCACCTTATAGATGCTTTAAATAGCTTTTGATTA TTTTTCCGATGTCACCTTTACTTTCTGGAACTCATGGCTTCACAAAATAGCTGATTTTAA AATATTTCTAATGAACTGATTAATGGGGGAAAAGAAAATATTGAACACGTTATAAATTTT TTACCATAAACAAATATGCATATCAAAAGATACTAACTTTAAAATGGTACAAAAAAAGGA AAAACCTGAATTACAGAAAAGTCAAATTTATTTAATGAAAAACTAAAATTAATAAAAATT AGCAAATACACACAAAAAAAGCACACAGCAGCACTATGTATTGACTCACAAAGGGAAAAG CAGTGGCCCATGACCACTCAAGATGGCTTGTCAGTTAAAGGAAAAAAACCCAAACACGCA CACACCCACGCATGCACACACTTCCACGCANAAACAACTTTTNTCAACATACATCAATCT ACACAAACACAAAACTCAGAATATTTTACAATGCTTCCTTTTCTTATTACAAAGATGCCA TCTTGGGTGTATATACATATATTNTTCCAGAGGTTACTGTTGACTTATTNTAAATATATT AGGGNTACTAACTGCACCTGTTTCCTGTTTTTACAAGCCTTCTTTTNATTTACCTCATGT GTCTAGCTTCCACCTACGAAGAGTTTTAGTGGCNAACGAGGTGCCTTT |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_003031 |
| Insert Size | 2180 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003031.3, NP_003022.3 |
| RefSeq Size | 2003 bp |
| RefSeq ORF | 849 bp |
| Locus ID | 6477 |
| UniProt ID | Q8IUQ4 |
| Domains | Sina |
| Protein Families | Druggable Genome |
| Protein Pathways | p53 signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway |
| Gene Summary | This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the smaller isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206576 | SIAH1 (Myc-DDK-tagged)-Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1 |
CNY 3,600.00 |
|
| RC206576L1 | Lenti ORF clone of Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC206576L2 | Lenti ORF clone of Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206576L3 | Lenti ORF clone of Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC206576L4 | Lenti ORF clone of Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RG206576 | SIAH1 (tGFP-tagged) - Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1 |
CNY 5,200.00 |
|
| SC323995 | SIAH1 (untagged)-Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1 |
CNY 2,400.00 |
