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CXCR3 (NM_001504) Human Untagged Clone
CAT＃: SC119210
CXCR3 (untagged)-Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A
CNY 5,488.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001504 edited
GAATTCGGCACCAGCAGCACACCACCCAGCAGCCAGAGCACCAGCCCAGCCATGGTCCTT GAGGTGAGTGACCACCAAGTGCTAAATGACGCCGAGGTTGCCGCCCTCCTGGAGAACTTC AGCTCTTCCTATGACTATGGAGAAAACGAGAGTGACTCGTGCTGTACCTCCCCGCCCTGC CCACAGGACTTCAGCCTGAACTTCGACCGGGCCTTCCTGCCAGCCCTCTACAGCCTCCTC TTTCTGCTGGGGCTGCTGGGCAACGGCGCGGTGGCAGCCGTGCTGCTGAGCCGGCGGACA GCCCTGAGCAGCACCGACACCTTCCTGCTCCACCTAGCTGTAGCAGACACGCTGCTGGTG CTGACACTGCCGCTCTGGGCAGTGGACGCTGCCGTCCAGTGGGTCTTTGGCTCTGGCCTC TGCAAAGTGGCAGGTGCCCTCTTCAACATCAACTTCTACGCAGGAGCCCTCCTGCTGGCC TGCATCAGCTTTGACCGCTACCTGAACATAGTTCATGCCACCCAGCTCTACCGCCGGGGG CCCCCGGCCCGCGTGACCCTCACCTGCCTGGCTGTCTGGGGGCTCTGCCTGCTTTTCGCC CTCCCAGACTTCATCTTCCTGTCGGCCCACCACGACGAGCGCCTCAACGCCACCCACTGC CAATACAACTTCCCACAGGTGGGCCGCACGGCTCTGCGGGTGCTGCAGCTGGTGGCTGGC TTTCTGCTGCCCCTGCTGGTCATGGCCTACTGCTATGCCCACATCCTGGCCGTGCTGCTG GTTTCCAGGGGCCAGCGGCGCCTGCGGGCCATGCGGCTGGTGGTGGTGGTCGTGGTGGCC TTTGCCCTCTGCTGGACCCCCTATCACCTGGTGGTGCTGGTGGACATCCTCATGGACCTG GGCGCTTTGGCCCGCAACTGTGGCCGAGAAAGCAGGGTAGACGTGGCCAAGTCGGTCACC TCAGGCCTGGGCTACATGCACTGCTGCCTCAACCCGCTGCTCTATGCCTTTGTAGGGGTC AAGTTCCGGGAGCGGATGTGGATGCTGCTCTTGCGCCTGGGCTGCCCCAACCAGAGAGGG CTCCAGAGGCAGCCATCGTCTTCCCGCCGGGATTCATCCTGGTCTGAGACCTCAGAGGCC TCCTACTCGGGCTTGTGAGGCCGGAATCCGGGCTCCCCTTTCGCCCACAGTCTGACTTCC CCGCATTCCAGGCTCCTCCCTCCCTCTGCCGGCTCTGGCTCTCCCCAATATCCTCGCTCC CGGGACTCACTGGCAGCCCCAGCACCACCAGGTCTCCCGGGAAGCCACCCTCCCAGCTCT GAGGACTGCACCATTGCTGCTCCTTAGCTGCCAAGCCCCATCCTGCCGCCCGAGGTGGCT GCCTGGAGCCCCACTGCCCTTCTCATTTGGAAACTAAAACTTCATCTTCCCCAAGTGCGG GGAGTACAAGGCATGGCGTAGAGGGTGCTGCCCCATGAAGCCACAGCCCAGGCCTCCAGC TCAGCAGTGACTGTGGCCATGGTCCCCAAGACCTCTATATTTGCTCTTTTATTTTTATGT CTAAAATCCTGCTTAAAACTTTTCAATAAACAAGATCGTCAGGAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_001504 unedited
AGGGGCAACCACNNTCCCCCCCCCCCCGTTCAAATTTGTATACGACTCACTATAGGCGGC CGCGAATTCGCACCAGCAGCACACCACCCAGCAGCCAGAGCACCAGCCCAGCCATGGTCC TTGAGGTGAGTGACCACCAAGTGCTAAATGACGCCGAGGTTGCCGCCCTCCTGGAGAACT TCAGCTCTTCCTATGACTATGGAGAAAACGAGAGTGACTCGTGCTGTACCTCCCCGCCCT GCCCACAGGACTTCAGCCTGAACTTCGACCGGGCCTTCCTGCCAGCCCTCTACAGCCTCC TCTTTCTGCTGGGGCTGCTGGGCAACGGCGCGGTGGCAGCCGTGCTGCTGAGCCGGCGGA CAGCCCTGAGCAGCACCGACACCTTCCTGCTCCACCTAGCTGTAGCAGACACGCTGCTGG TGCTGACACTGCCGCTCTGGGCAGTGGACGCTGCCGTCCAGTGGGTCTTTGGCTCTGGCC TCTGCAAAGTGGCAGGTGCCCTCTTCAACATCAACTTCTACGCAGGAGCCCTCCTGCTGG CCTGCATCAGCTNTGACCGCTACCTGAACATAGTTCATGCCACCCAGCTCTACCGCCGGN GGCCCCCGGCCCGCGTGACCCTCACCTGCCTGGCTGTCTGGNGGCTCTGCCTGCTTTTCG CCCTCCCAGACTTCATCTTCCTGTNCGCCCACCACGACGAGCGCCTCAACGCCACCCACT GNCAATACAACTTNCCACAGGTGGGCCGCACGGCTCTGCGGNTGCTGCAACTGGTGCCTT GGCTTTCTGCTGCCCCTGCTGGTCATGGCCTACTGCTATGCCCACATCCTGGCCGTGCTG CNTGGNTTTCAGGGGCCCAGCGCGCCCTGCGGGCATGCGGCTTGTNGTGGNGGGCCCTGG TGGCCTTTGCCTTCTGCTGGNACCCCTTCCACCTGTGGNGCCTGGGGACACTNCTCATGG ACCTGGNCGCTTTTGGCCGGCACCGTGGGCG >OriGene 3' read for NM_001504 unedited
TACNATGATCGATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TCTCCGGACAATCTTGTTTATTGAAAAAGTTTTAACCAGGATTTTAAACCTAAAAATAAA AAACCAAATTTAGAGGTCTTGGGGACCATGGCCACAGTCACTGCTGACCTGGAGGCCTGG GCTGGGGCTTCATGGGGAAACACCCTTTACCCCATGCCTTGTACTCCCCGCACTTGGGAA AAATAAATTTTTATTTTCCAAATGAAAAGGGCAGGGGGGCTCCAGGCAGCCACCTCGGGC GGCAGGATGGGGCTTGGCACCTAAGGACCACCAATGGGGCAGCCCTCAAAGCTGGGAGGG GGGCTTCCCGGAAAACCTGGGGGGGCTGGGGCTGCCAGTGATTCCCGGGAGCGAGGATTT TGGGGAAAGCCAAACCCGGCCAAAGGGAGGGAGGACCCTGGAATGCGGGGAATTCAAACT GGGGGCAAAAGGGGACCCCGGATTCCGGCCTCACAACCCCGATTAGGAGGCCTCTGAGGT CTCAAACCAGGATGAATCCCGGCGGGAAAACAATGGCTGCCTCTGGACCCCTCTTTGGTT GGGGCATCCCAGGCGCAAAATCATATCCAAATTCCGCTCCCGGAACTTGACCCCTACAAA GGCATAAACCACCGGGTTGAGGCCCCATTGCTTGTACCCCCAAGCCCGGAGGGGACCCCA TTTGGCCAGTTCTACCCTGGGTTTCTTGGCCAAAATTGGGGGGCGAAAACCCCCCAGGCC CATGGAGATGTTCCCCCCCCCCCCCCCGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001504 |
| Insert Size | 1750 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001504.1, NP_001495.1 |
| RefSeq Size | 1670 bp |
| RefSeq ORF | 1107 bp |
| Locus ID | 2833 |
| UniProt ID | P49682 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011] Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1 (also known as CXCR3-A). This isoform functions as a receptor for chemokines CXCL9/Mig, CXCL10/IP-10, and CXCL11/I-TAC (PMID:12782716). |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206596 | CXCR3 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A |
CNY 3,990.00 |
|
| RC206596L1 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206596L2 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A, mGFP tagged |
CNY 5,890.00 |
|
| RC206596L3 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206596L4 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A, mGFP tagged |
CNY 5,890.00 |
|
| RG206596 | CXCR3 (tGFP-tagged) - Human chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant A |
CNY 4,370.00 |
