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COX10 (NM_001303) Human Untagged Clone
CAT＃: SC119292
COX10 (untagged)-Human COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (COX10), nuclear gene encoding mitochondrial protein
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MC4DN3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001303, the custom clone sequence may differ by one or more nucleotides
ATGGCCGCATCTCCGCACACTCTCTCCTCACGCCTCCTGACAGGTTGCGTAGGAGGCTCTGTCTGGTATC TTGAAAGAAGAACTATACAGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTG GATTACATTTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGAACAGAAGCCACAACCAG CAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAGGTCAAGCCAAAG CAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGTCCAGAAAGCCAAATGAAAAGGA ATTGATAGAACTAGAGCCAGACTCAGTAATTGAAGACTCAATAGATGTAGGGAAAGAGACAAAAGAGGAA AAGCGGTGGAAAGAGATGAAGCTGCAAGTGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCA AACTCACAGCTCTGGTTGTAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCC CTGTTTCCTGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTTTTT GAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCAT TGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATC AGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCA CGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAA CGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCG GGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGC TGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTT CCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCG CTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCT GA >OriGene 5' read for NM_001303 unedited
TCGATTTGATACATTATTAGGCGGCCGCGATTCGCACGAGCCCGTGAGAGAGAGACACAG GATCCCGGGGAGCGGCCCCAGACTCGTAAATTATGGCCGCATCTCCGCACACTCTCTCCT CACGCCTCCTGACAGGTTGCGTAAGAGGCTCTGTCTGGTATCTTGAAAGAAGAACTATAC AGGACTCCCCTCACAAGTTCTTACATCTTCTCAGGAATGTCAATAAGCAGTGGATTACAT TTCAGCACTTTAGCTTCCTCAAACGCATGTATGTCACACAGCTGAACAGAAGCCACAACC AGCAAGTAAGACCCAAGCCAGAACCAGTAGCATCTCCTTTCCTTGAAAAAACATCTTCAG GTCAAGCCAAAGCAGAAATATATGAGATGAGACCTCTCTCACCGCCCAGCCTATCTTTGT CCAGAAAGCCAAATGAAAAGGAATTGATAGAACTAGAGCCAGACTCAGTAATTGAAGACT CAATAGATGTAGGGAAAGAGACAAAAGATGAAAAGCGGTGGAAAGAGATGAAGCTGCAAG TGTATGATTTGCCAGGAATTTTGGCTCGACTATCCAAAATCAAACTCACAGCTCTAGTTG TAAGTACCACTGCAGCTGGATTTGCATTGGCTCCGGGCCCTTTTGACTGGCCCTGTTTCC TGCTTACTTCTGTTGGGACAGGCCTTGCATCCTGTGCTGCCAACTCCATCAATCAGTTNT TTAGAGTGCCATTTGACTCANACATGAATAGGACANAGAACAGACCGCTGGTTCGTGGAC AGATCAGCCCGTTGCTAGCTGTGTCCTTTGCCACCTAGTGTGCTGNTCCGGGAGTTGCCA TTCTGACCNTGGAGGTGAATCCACTCACAGGAGCCCTGGGGCTNNCTCACATTTTCTGGT TACCTGCTGCTACCACCACTGAAAAGATCAGCATTGCCACCCATGGTCG >OriGene 3' read for NM_001303 unedited
TTACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTATACCATTTTATT GTGGAAGGAAAAGAGAATCAATGAATTGTACAAATGTGAAGGCTGTAACAAGTTGTAGAG GCTTTTTCCAGACATTCCTATGCAATGTTCTCCACAGTAAATACCTGGGGGCAGCCAAGA GGGAAGATTTCAGATAAGTGCAAACAGTGATTGGATGTTATCTACCTACAATCCCTTTAG ACATTTTTGAGAGAACTCTGTTTAAATGTTGTTTAACTCTCCCACCCCGACCAATGAATC CCTACGGACCAGCAGTGCCCTGGGAGACTGAGTAATGAAAACATCCTGTCAAGCTTCAAG ACCTTTGGGCAGATGGGACTCTGCAGACCCGTGGGAGCACAAAGGACTAAAAAGCTGCAG GTAACCGTGTTTGGTAACCGAGACCACACCTGGCCACAGGATAACTTGCAAAATTCCCAG AACCCTGCTTCTGGCTCTTAAAGCCATTGCACATGTGGAGGCTAATTTCTGAATTCAGGA GATATCAGGATGGACATGTATTTTTCACCCAAGGGACAGGAATGTGAGCTCTGTGGGCTG GTTAGCCCAGCACACCCTTCTTCCTAACTTCCCTTCTCATACAGCCTTGAAAAGCCGTGC TGTGTAGCAGGAGTGGCGACCCACAGTAGTGACTCCAGAGGTACAGTAATGGGGGTGGGG GCCAGAGGTATCCCGGCTGGTATTNAGGTCCAGGGCCTACCCTTTTAGAAAGAACTGGCT TCCACAGTGTCTATATGTTAACGTGAACTATNAAGATGGCTGTGACTTCCTTGGNATTTC TGAAATGCTCATACGCAATGTGGGTGAAAGGGAGGACAGGGCCCTGCCAATCCAACCTGG AGACT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001303 |
| Insert Size | 2800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001303.2, NP_001294.2 |
| RefSeq Size | 3031 bp |
| RefSeq ORF | 1332 bp |
| Locus ID | 1352 |
| UniProt ID | Q12887 |
| Domains | UbiA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, Oxidative phosphorylation, Porphyrin and chlorophyll metabolism |
| Gene Summary | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200624 | COX10 (Myc-DDK-tagged)-Human COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (COX10), nuclear gene encoding mitochondrial protein |
CNY 3,656.00 |
|
| RC200624L3 | Lenti ORF clone of Human COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (COX10), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200624L4 | Lenti ORF clone of Human COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (COX10), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
| RG200624 | COX10 (tGFP-tagged) - Human COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (COX10), nuclear gene encoding mitochondrial protein |
CNY 4,370.00 |
