5 HT1A (HTR1A) (NM_000524) Human Untagged Clone
CAT＃: SC119816
HTR1A (untagged)-Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A)
CNY 3656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000524, the custom clone sequence may differ by one or more nucleotides
ATGGATGTGCTCAGCCCTGGTCAGGGCAACAACACCACATCACCACCGGCTCCCTTTGAGACCGGCGGCA ACACTACTGGTATCTCCGACGTGACCGTCAGCTACCAAGTGATCACCTCTCTGCTGCTGGGCACGCTCAT CTTCTGCGCGGTGCTGGGCAATGCGTGCGTGGTGGCTGCCATCGCCTTGGAGCGCTCCCTGCAGAACGTG GCCAATTATCTTATTGGCTCTTTGGCGGTCACCGACCTCATGGTGTCGGTGTTGGTGCTGCCCATGGCCG CGCTGTATCAGGTGCTCAACAAGTGGACACTGGGCCAGGTAACCTGCGACCTGTTCATCGCCCTCGACGT GCTGTGCTGCACCTCATCCATCTTGCACCTGTGCGCCATCGCGCTGGACAGGTACTGGGCCATCACGGAC CCCATCGACTACGTGAACAAGAGGACGCCCCGGCGCGCCGCTGCGCTCATCTCGCTCACTTGGCTTATTG GCTTCCTCATCTCTATCCCGCCCATGCTGGGCTGGCGCACCCCGGAAGACCGCTCGGACCCCGACGCATG CACCATTAGCAAGGATCATGGCTACACTATCTATTCCACCTTTGGAGCTTTCTACATCCCGCTGCTGCTC ATGCTGGTTCTCTATGGGCGCATATTCCGAGCTGCGCGCTTCCGCATCCGCAAGACGGTCAAAAAGGTGG AGAAGACCGGAGCGGACACCCGCCATGGAGCATCTCCCGCCCCGCAGCCCAAGAAGAGTGTGAATGGAGA GTCGGGGAGCAGGAACTGGAGGCTGGGCGTGGAGAGCAAGGCTGGGGGTGCTCTGTGCGCCAATGGCGCG GTGAGGCAAGGTGACGATGGCGCCGCCCTGGAGGTGATCGAGGTGCACCGAGTGGGCAACTCCAAAGAGC ACTTGCCTCTGCCCAGCGAGGCTGGTCCTACCCCTTGTGCCCCCGCCTCTTTCGAGAGGAAAAATGAGCG CAACGCCGAGGCGAAGCGCAAGATGGCCCTGGCCCGAGAGAGGAAGACAGTGAAGACGCTGGGCATCATC ATGGGCACCTTCATCCTCTGCTGGCTGCCCTTCTTCATCGTGGCTCTTGTTCTGCCCTTCTGCGAGAGCA GCTGCCACATGCCCACCCTGTTGGGCGCCATAATCAATTGGCTGGGCTACTCCAACTCTCTGCTTAACCC CGTCATTTACGCATACTTCAACAAGGACTTTCAAAACGCGTTTAAGAAGATCATTAAGTGTAAGTTCTGC CGCCAGTGA >OriGene 5' read for NM_000524 unedited
ATTTTGTAATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGCAGCTCCGGCAG CCAGTTCGGGAGCGGCAAAGTAAAATGGACAGCGACAGACAGACGTTCCAGCCACCTCTC CGCCGCCGGGAGATCCTGGAGCTGCTTTCAGGCCAACTCCAGTTTCCCAGCTGGAGCTTC TGAACGCGCTGGACTGCGAGAGCCCAGGGAGCGCCTGAAAGCTGCTCCTCGGAGATACCC TTCGCCGAAGCAGTAAGAACTTCCTGCTTGGGTCTCTGCATTCCCTTCCTCCGAAACTTC CCAGGAGAAGGGCGGAAGACCCCAGGGGAAGGGGCGAGGCGAATCTTCGCGCTGCTTTTT CTTCCCTCCCCCTTCCCGCGCCGGGCGCGCAGGCATGGATGTGCTCAGCCCTGGTCAGGG CAACAACACCACATCACCACCGGCTCCCTTTGAGACCGGCGGCAACACTACTGGTATCTC CGACGTGACCGTCAGCTACCAAGTGATCACCTCTCTGCTGCTGGGCACGCTCATCTTCTG CGCGGTGCTGGGCAATGCGTGCGTGGTGGCTGCCATCGCCTTGGAGCGCTCCCTGCAGAA CGTGGCCAATTATCTTATTGGCTCTTTGGCGGTCACCGACCTCATGGTGGTCGGTGTTGG GTGCTGCCCATGGCCGCGCTGTATCAGGTGCTCAACAAGTGGACACTGGGCCAGGTAACC TGCGACCTNGTCATCGCCCTCGACGTGCTGTGCTGCACCTCATCCATCTTGCACCTGTGG CGCATCGCGCTGGACAGGTACTGGGCCATCACGGACCCCATCGACTACGTGAACAGAGGA CGCCCGGGCGCCGCGNTN >OriGene 3' read for NM_000524 unedited
AATCNTGNCCGCGGCCGCATCTANAGTCGGTTTTTTTTTTTTTTTTTTTTTTTTTGAGAA ATGCAGCTATTTTATTTCTCTAAATTCTCTATTGCCTTGACAATTATGCTCCAGTTGGAT GTTCCTTCTCCATTCTTGGGTAAATATTCCAAAGCCGAAAGAACAAATGTCCAAAAGTCA TTGTCATACAATTCTGTAAAAGACACAAATAAATGGAAGTCTCAAAACTTCTAATGTAAA ACTTGCTGGCCAAGACATAATTTGGATGAGCAAATTTGGGGTTTGGATTATTTTAAATAT AGACTTTGTTCTTAAAATTTAGTGTAACATACAGAAAAACTTGGTTTCTGATATGGCTTT ACTTAGATTATGTGAGCAAAAATGAAACTGAATTATCAAATGAGTAATAGTTGTGCTGGA GAAGTCTATCTTATCTTCTTCACTGCAGACCCTTCTCAGCATTATACATGCATAGACAAA CTATTCCCAAAGTTCTAAAACTTTCCCTGTTTAGCTGGGATATGATGTCTACTTCCAGGT TAGAACACAGAAGCCCACACCCAAGGAAAGCTTTGTTCAATCTGACAAACAATAAAATGG CTTTAACTGACAGAGCTGGCCTTTCACTTTTTTAAATATAAAGAAAGAACTTCTCACTGG CAATTTTTGCAACCCGTAAACGCTATCCGGTTTTTCAAACCACCCAATGAAACACTTCCA AAGGTCCCCGTTTGACCACAACAAGAATCCGGGACACATTACTTTGGGAAATTTTTGGGA AAACAAGACCATTATTTATAAGAAAAATGGCGGGTTCAATTAAACACAGGCCAACCTTCT CATCCCCCTCCCGCGGCTTGGGCCAACCACCCTCCCGGGTACCCTACTAATTTTTCTCTT TTGTGGGTAAAAAGACTTCACCACCTCCCCCCGCCAAGGATGCCCACGGCTCCCCAAACA CCCGTAAAGGAGAAAACCCCGGCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000524 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000524.2, NP_000515.2 |
| RefSeq Size | 1269 bp |
| RefSeq ORF | 1269 bp |
| Locus ID | 3350 |
| UniProt ID | P08908 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Sedative and hypnotic effects of Vaccinium bracteatum Thunb. through the regulation of serotonegic and GABAA-ergic systems: Involvement of 5-HT1A receptor agonistic activity
,Oh, D;Kim, Y;Jo, A;Choi, E;Oh, K;Kim, J;Kang, H;Kim, Y;Choi, C;,
Biomedicine & Pharmacotherapy
,PubMed ID 30551479
[HTR1A]
|
|
Brexpiprazole I: In vitro and in vivo characterization of a novel serotonin-dopamine activity modulator
,Maeda, K;Sugino, H;Akazawa, H;Amada, N;Shimada, J;Futamura, T;Yamashita, H;Ito, N;McQuade, RD;Mork, A;Pehrson, AL;Hentzer, M;Nielsen, V;Bundgaard, C;Arnt, J;Stensbol, TB;Kikuchi, T;,
J. Pharmacol. Exp. Ther.
,PubMed ID 24947465
[HTR1A]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218011 | HTR1A (Myc-DDK-tagged)-Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A) |
CNY 3656.00 |
|
| RC218011L1 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), Myc-DDK-tagged |
CNY 6056.00 |
|
| RC218011L2 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), mGFP tagged |
CNY 5890.00 |
|
| RC218011L3 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC218011L4 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), mGFP tagged |
CNY 6056.00 |
|
| RG218011 | HTR1A (tGFP-tagged) - Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A) |
CNY 5256.00 |
