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SCNN1B (NM_000336) Human Untagged Clone
CAT＃: SC119979
SCNN1B (untagged)-Human sodium channel, nonvoltage-gated 1, beta (SCNN1B)
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BESC1; ENaCb; ENaCbeta; LIDLS1; SCNEB |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000336 edited
CGGCACGAGGCGCATCCTCCGTGTCCCCGCTCCGCCGCCCGAGCAGGTGCCACTATGCAC GTGAAGAAGTACCTGCTGAAGGGCCTGCATCGGCTGCAGAAGGGCCCCGGCTACACGTAC AAGGAGCTGCTGGTGTGGTACTGCGACAACACCAACACCCACGGCCCCAAGCGCATCATC TGTGAGGGGCCCAAGAAGAAAGCCATGTGGTTCCTGCTCACCCTGCTCTTCGCCGCCCTC GTCTGCTGGCAGTGGGGCATCTTCATCAGGACCTACTTGAGCTGGGAGGTCAGCGTCTCC CTCTCCGTAGGCTTCAAGACCATGGACTTCCCCGCCGTCACCATCTGCAATGCTAGCCCC TTCAAGTATTCCAAAATCAAGCATTTGCTGAAGGACCTGGATGAGCTGATGGAAGCTGTC CTGGAGAGAATCCTGGCTCCTGAGCTAAGCCATGCCAATGCCACCAGGAACCTGAACTTC TCCATCTGGAACCACACACCCCTGGTCCTTATTGATGAACGGAACCCCCACCACCCCATG GTCCTTGATCTCTTTGGAGACAACCACAATGGCTTAACAAGCAGCTCAGCATCAGAAAAG ATCTGTAATGCCCACGGGTGCAAAATGGCCATGAGACTATGTAGCCTCAACAGGACCCAG TGTACCTTCCGGAACTTCACCAGTGCTACCCAGGCATTGACAGAGTGGTACATCCTGCAG GCCACCAACATCTTTGCACAGGTGCCACAGCAGGAGCTAGTAGAGATGAGCTACCCCGGC GAGCAGATGATCCTGGCCTGCCTATTCGGAGCTGAGCCCTGCAACTACCGGAACTTCACG TCCATCTTCTACCCTCACTATGGCAACTGTTACATCTTCAACTGGGGCATGACAGAGAAG GCACTTCCTTCGGCCAACCCTGGAACTGAATTCGGCCTGAAGTTGATCCTGGACATAGGC CAGGAAGACTACGTCCCCTTCCTTGCGTCCACGGCCGGGGTCAGGCTGATGCTTCACGAG CAGAGGTCATACCCCTTCATCAGAGATGAGGGCATCTACGCCATGTCGGGGACAGAGACG TCCATCGGGGTACTCGTGGACAAGCTTCAGCGCATGGGGGAGCCCTACAGCCCGTGCACC GTGAATGGTTCTGAGGTCCCCGTCCAAAACTTCTACAGTGACTACAACACGACCTACTCC ATCCAGGCCTGTCTTCGCTCCTGCTTCCAAGACCACATGATCCGTAACTGCAACTGTGGC CACTACCTGTACCCACTGCCCCGTGGGGAGAAATACTGCAACAACCGGGACTTCCCAGAC TGGGCCCATTGCTACTCAGATCTACAGATGAGCGTGGCGCAGAGAGAGACCTGCATTGGC ATGTGCAAGGAGTCCTGCAATGACACCCAGTACAAGATGACCATCTCCATGGCTGACTGG CCTTCTGAGGCCTCCGAGGACTGGATTTTCCACGTCTTGTCTCAGGAGCGGGACCAAAGC ACCAATATCACCCTGAGCAGGAAGGGAATTGTCAAGCTCAACATCTACTTCCAAGAATTT AACTATCGCACCATTGAAGAATCAGCAGCCAATAACATCGTCTGGCTGCTCTCGAATCTG GGTGGCCAGTTTGGCTTCTGGATGGGGGGCTCTGTGCTGTGCCTCATCGAGTTTGGGGAG ATCATCATCGACTTTGTGTGGATCACCATCATCAAGCTGGTGGCCTTGGCCAAGAGCCTA CGGCAGCGGCGAGCCCAAGCCAGCTACGCTGGCCCACCGCCCACCGTGGCCGAGCTGGTG GAGGCCCACACCAACTTTGGCTTCCAGCCTGACACGGCCCCCCGCAGCCCCAACACTGGG CCCTACCCCAGTGAGCAGGCCCTGCCCATCCCAGGCACCCCGCCCCCCAACTATGACTCC CTGCGTCTGCAGCCGCTGGACGTCATCGAGTCTGACAGTGAGGGTGATGCCATCTAACCC TGCCCCTGCCCACCCCGGGCGGCTGAAACTCACTGAGCAGCCAAGACTGTTGCCCGAGGC CTCACTGTATGGTGCCCTCTCCAAAGGGTCGGGAGGGTAGCTCTCCAGGCCAGAGCTTGT GTCCTTCAACAGAGAGGCCAGCGGCAACTGGTCCGTTACTGGCCAAGGGCTCTGTAGAAT CACGGTGCTGGTACAGGATGCAGGAATAAATTGTATCTTCACCTGGTTCCTACCCTCGTC CCTACCTGTCCTGATCCTGGTCCTGAAGACCCCTCGGAACACCCTCTCCTGGTGGCAGGC CACTTCCCTCCCAGTGCCAGTCTCCATCCACCCCAGAGAGGAACAGGCGGGTGGGCCATG TGGTTTTCTCCTTCCTGGCCTTGGCTGGCCTCTGGGGCAGGGGTGGTGGAGAGATGGAAG GGCATCAGGTGTAGGGACCCTGCCAAGTGGCACCTGATTTACTCTAGAAAATAAAAGTAG AAAAT >OriGene 5' read for NM_000336 unedited
NGGGATTTCAGGATATTTGTNAATCCGNACTTTACTNTNAGGGNCGGCACGCGCAATTCG GCACGAGGCGCATCCTCCGTGTCCCCGCTCCGCCGCCCGAGCAGGTGCCACTATGCACGT GAAGAATACCTGCTGAAGGGCCTGCATCGGCTGCAGAAGGGCCCCGGCTACACGTACAAG GAGCTGCTGGTGTGGTACTGCGACAACACCAACACCCACGGCCCCAAGCGCATCATCTGT GAGGGGCCCAAGAAGAAAGCCATGTGGTTCCTGCTCACCCTGCTCTTCGCCGCCCTCGTC TGCTGGCAGTGGGGCATCTTCATCAGGACCTACTTGAGCTGGGAGGTCAGCGTCTCCCTC TCCGTAGGCTTCAAGACCATGGACTTCCCCGCCGTCACCATCTGCAATGCTAGCCCCTTC AAGTATTCCAAAATCAAGCATTTGCTGAAGGACCTGGATGAGCTGATGGAAGCTGTCCTG GAGAGAATCCTGGCTCCTGAGCTAAGCCATGCCAATGCCACCAGGAACCTGAACTTCTCC ATCTGGAACCACACACCCCTGGTCCTTATTGATGAACGGAACCCCCACCACCCCATGGTC CTTGATCTCTTTGGAGACAACCACAATGGCTTAACAAGCAGCTCAGCATCAGAAAAGATC TGNTATGCCCACGGGTGCAAAATGGCCATGAGACTATGTAGCCTCAACAGGACCCAGTGT ACCTTCCGGAACTTCACCAGTGCTACCCCAGCATTGACAGAGTGGTACATCCTGCNAGCC ACCAACATCTTTGCACAGGTGCCACAGCANGAGCTAGTAGAGATGAGCTACCCCGGCCAG CAGATGATCCTGGCCTGCCTATTCGGAACTGAGCCTGNAACTACCGGAACTTACGTCCAT TTNCTACCCTTACTAGG >OriGene 3' read for NM_000336 unedited
AAAAAAACCTACTAGTACCGCGCCGCGTGCNATGATCGATTTTTTTTTTTTTTTTTTCAT ATTTTCTACTTTTATTTTCTAGAGTAAATCAGGTGCCACTTGGCAGGGTCCCTACACCTG ATGCCCTTCCATCTCTCCACCACCCCTGCCCCAGAGGCCAGCCAAGGCCAGGAAGGAGAA AACCACATGGCCCACCCGCCTGTTCCTCTCTGGGGTGGATGGAGACTGGCACTGGGAGGG AAGTGGCCTGCCACCAGGAGAGGGTGTTCCGAGGGGTCTTCAGGACCAGGATCAGGACAG GTAGGGACGAGGGTAGGAACCAGGTGAAGATACAATTTATTCCTGCATCCTGTACCAGCA CCGTGATTCTACAGAGCCCTTGGCCAGTAACGGACCAGTTGCCGCTGGCCTCTCTGTTGA AGGACACAAGCTCTGGCCTGGAGAGCTACCCTCCCGACCCTTTGGAGAGGGCACCATACA GTGAGGCCTCGGGCAACAGTCTTGGCTGCTCAGTGAGTTTCAGCCGCCCGGGGTGGGCAG GGGCAGGGTTAGATGGCATCACCCTCACTGTCAGACTCGATGACGTCCAGCGGCTGCAGA CGCAGGGAGTCATATTTGGGGGGCGGGGTGCCTGGGATGGGCAGGGCCTGCTCACTGGGG TAGGGCCCAGTGTTGGGGCTGCGGGGGGCCGTGTCANGCTGGAAGCCAAAGTTGGTGTGG GCCTCCACCAGCTCGGCCACGGTGGGCGGTGGGCCAGCGTAGCTGGCTTGGGCTCGCCGC TGCCGTTAGCTCTTGGCCAAGCCACCAGCTTGATGATGGTGATCCACACAAAGTCCATGA TGATCTCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000336 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000336.1, NP_000327.1 |
| RefSeq Size | 2564 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 6338 |
| UniProt ID | P51168 |
| Domains | ASC |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Protein Pathways | Taste transduction |
| Gene Summary | Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Selective Activation of hTRPV1 by N-Geranyl Cyclopropylcarboxamide, an Amiloride-Insensitive Salt Taste Enhancer
,Kim, MJ;Son, HJ;Kim, Y;Kweon, HJ;Suh, BC;Lyall, V;,
PLOS ONE, Feb 2014.
[SCNN1B]
|
|
Expression, Transcription, and Possible Antagonistic Interaction of the Human Nedd4L Gene Variant: Implications for Essential Hypertension
,Naomi Araki, Masanari Umemura, Yohei Miyagi, Machiko Yabana, Yuko Miki, Koichi Tamura, Kazuaki Uchino, Reina Aoki, Yoshio Goshima, Satoshi Umemura, and Tomoaki Ishigami,
Hypertension, Mar 2008; 51: 773 - 777.
[SCNN1B]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206580 | SCNN1B (Myc-DDK-tagged)-Human sodium channel, nonvoltage-gated 1, beta (SCNN1B) |
CNY 4,560.00 |
|
| RC206580L3 | Lenti ORF clone of Human sodium channel, nonvoltage-gated 1, beta (SCNN1B), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC206580L4 | Lenti ORF clone of Human sodium channel, nonvoltage-gated 1, beta (SCNN1B), mGFP tagged |
CNY 6,460.00 |
|
| RG206580 | SCNN1B (tGFP-tagged) - Human sodium channel, nonvoltage-gated 1, beta (SCNN1B) |
CNY 5,040.00 |
