L2HGDH (BC006117) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	2-hydroxyglutarate dehydrogenase; alpha-hydroxyglutarate oxidoreductase; alpha-ketoglutarate reductase; C14orf160; DURANIN; FLJ12618; L-2-hydroxyglutarate dehydrogenase; L-alpha-hydroxyglutarate dehydrogenase
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC006117 edited AATTCGACACGAGGGGGGAGCGTGCGTAGGGGATGGTGCCAGCGCTGCGTTATTTGGTTG GTGCCTGCGGACGGGCCCGCGGGCGTTTCGCCGGTGGCTCCCCTGGGGCGTGCGGGTTCG CGTCTGGGAGGCCAAGACCGCTGTGTGGAGGTAGCCGCAGCGCCAGCACCAGCTCATTTG ATATAGTCATTGTTGGTGGCGGAATTGTGGGGCTTGCCTCTGCCAGAGCACTCATCCTGC GACATCCATCACTTTCTATTGGTGTTCTGGAAAAGGAGAAAGATTTAGCTGTTCACCAGA CTGGACATAACAGTGGTGTCATACATAGTGGAATTTATTATAAACCTGAGTCTCTGAAAG CCAAATTATGTGTACAAGGTGCAGCCCTCCTCTATGAGTACTGTCAGCAAAAGGGAATTT CCTACAAGCAGTGTGGCAAGCTTATAGTAGCTGTTGAACAAGAAGAAATTCCCAGACTTC AGGCCCTATATGAGAAAGGCCTCCAGAATGGTGTCCCGGGCCTGAGGCTGATCCAGCAGG AGGATATAAAAAAGAAGGAGCCATATTGTAGGGGTCTAATGGCTATTGATTGTCCACATA CTGGCATTGTGGACTATCGGCAGGTGGCTTTGTCATTTGCCCAGGATTTCCAAGAAGCAG GTGGCTCTGTCTTGACCAATTTTGAAGTAAAAGGTATTGAAATGGCTAAAGAAAGTCCTT CAAGAAGTATAGATGGAATGCAATATCCAATTGTTATAAAGAATACAAAGGGAGAGGAAA TTCGATGTCAGTATGTTGTGACATGTGCAGGACTTTACTCAGACCGTATTTCAGAGTTGA GTGGCTGCACTCCTGATCCTCGAATTGTACCATTCCGGGGAGATTACCTGCTTTTGAAGC CAGAAAAATGTTATCTTGTAAAAGGAAATATTTATCCGGTCCCAGATAGCCGGTTTCCTT TCCTAGGAGTTCACTTCACACCAAGGATGGATGGCAGTATTTGGCTAGGGCCTAATGCAG TTCTTGCCTTTAAACGAGAGGGTTACAGACCCTTTGACTTCAGTGCCACAGATGTTATGG ATATAATTATCAATAGTGGCTTGATTAAACTGGCATCCCAGAATTTTTCCTATGGAGTTA CTGAAATGTATAAAGCATGTTTTCTTGGTGCAACAGTGAAGTATCTTCAAAAATTCATCC CTGAAATTACTATCAGTGATATACTTAGGCAGGTGGCTGTGAGAGGACCGAGCTGGCTAT GGCAGCAACCCATGAAAGTGAGTGATAACAACATTTATTGTTTCCTGTGGCGTTGCTTTG CTTTGCTATTGACTGGTAGCACTTGTAGCTTTAAATAAATTGAGGAAGTATGAGAGAGTA AATGGAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC006117 unedited NNNAATAGCGGACAGAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGACACAGGG GGGAGCGTGCGTAGGGGATGGTGCCAGCGCTGCGTTATTTGGTTGGTGCCTGCGGACGGG CCCGCGGGCGTTTCGCCGGTGGCTCCCCTGGGGCGTGCGGGTTCGCGTCTGGGAGGCCAA GACCGCTGTGTGGAGGTAGCCGCAGCGCCAGCACCAGCTCATTTGATATAGTCATTGTTG GTGGCGGAATTGTGGGGCTTGCCTCTGCCAGAGCACTCATCCTGCGACATCCATCACTTT CTATTGGTGTTCTGGAAAAGGAGAAAGATTTAGCTGTTCACCAGACTGGACATAACAGTG GTGTCATACATAGTGGAATTTATTATAAACCTGAGTCTCTGAAAGCCAAATTATGTGTAC AAGGTGCAGCCCTCCTCTATGAGTACTGTCAGCAAAAGGGAATTTCCTACAAGCAGTGTG GCAAGCTTATAGTAGCTGTTGAACAAGAAGAAATTCCCAGACTTCAGGCCCTATATGAGA AAGGCCTCCAGAATGGTGTCCCGGGCCTGAGGCTGATCCAGCAGGAGGATATAAAAAAGA AGGAGCCATATTGTAGGGGTCTAATGGCTATTGATTGTCCACATACTGGCATTGTGGACT ATCGGCAGGTGGCTTTGTCATTTGCCCAGGATTTCCAAGAAGCAGGTGGCTCTGTCTTGA CCAATTTTGAAGTAAAAGGTATTGAAATGGCTAAAGAAAGTCCTTCAAGAAGTATAGATG GAATGCAATATCCAATTGTTATAAAGAATACAAAGGGAGAGGAAATTCGATGTCAGTATG TTGTGACATGTGCAGGACTTTACTCAGACCGTATTTCAGATTTGAGTGGCTGCACTCC
Restriction Sites	Please inquire
ACCN	BC006117
Insert Size	1400 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC006117.1, AAH06117.1
RefSeq Size	1404 bp
Locus ID	79944
Protein Pathways	Butanoate metabolism
Gene Summary	This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]

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