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LEFTY2 (NM_003240) Human Untagged Clone
CAT＃: SC122648
LEFTY2 (untagged)-Human left-right determination factor 2 (LEFTY2), transcript variant 1
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EBAF; LEFTA; LEFTYA; TGFB4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003240 edited
CTGAGACCCTCCTTCAACCTCCCTAGAGGACAGCCCCACTCTGCCTCCTGCTCCCCCAGG GCAGCACCATGTGGCCCCTGTGGCTCTGCTGGGCACTCTGGGTGCTGCCCCTGGCTGGCC CCGGGGCGGCCCTGACCGAGGAGCAGCTCCTGGGCAGCCTGCTGCGGCAGCTGCAGCTCA GCGAGGTGCCCGTACTGGACAGGGCCGACATGGAGAAGCTGGTCATCCCCGCCCACGTGA GGGCCCAGTATGTAGTCCTGCTGCGGCGCAGCCACGGGGACCGCTCCCGCGGAAAGAGGT TCAGCCAGAGCTTCCGAGAGGTGGCCGGCAGGTTCCTGGCGTCGGAGGCCAGCACACACC TGCTGGTGTTCGGCATGGAGCAGCGGCTGCCGCCCAACAGCGAGCTGGTGCAGGCCGTGC TGCGGCTCTTCCAGGAGCCGGTCCCCAAGGCCGCGCTGCACAGGCACGGGCGGCTGTCCC CGCGCAGCGCCCAGGCCCGGGTGACCGTCGAGTGGCTGCGCGTCCGCGACGACGGCTCCA ACCGCACCTCCCTCATCGACTCCAGGCTGGTGTCCGTCCACGAGAGCGGCTGGAAGGCCT TCGACGTGACCGAGGCCGTGAACTTCTGGCAGCAGCTGAGCCGGCCCCGGCAGCCGCTGC TGCTACAGGTGTCGGTGCAGAGGGAGCATCTGGGCCCGCTGGCGTCCGGCGCCCACAAGC TGGTCCGCTTTGCCTCGCAGGGGGCGCCAGCCGGGCTTGGGGAGCCCCAGCTGGAGCTGC ACACCCTGGACCTCAGGGACTATGGAGCTCAGGGCGACTGTGACCCTGAAGCACCAATGA CCGAGGGCACCCGCTGCTGCCGCCAGGAGATGTACATTGACCTGCAGGGGATGAAGTGGG CCAAGAACTGGGTGCTGGAGCCCCCGGGCTTCCTGGCTTACGAGTGTGTGGGCACCTGCC AGCAGCCCCCGGAGGCCCTGGCCTTCAATTGGCCATTTCTGGGGCCGCGACAGTGTATCG CCTCGGAGACTGCCTCGCTGCCCATGATCGTCAGCATCAAGGAGGGAGGCAGGACCAGGC CCCAGGTGGTCAGCCTGCCCAACATGAGGGTGCAGAAGTGCAGCTGTGCCTCGGATGGGG CGCTCGTGCCAAGGAGGCTCCAGCCATAGGCGCCTGGTGTATCCATTGAGCCCTCTAACT GAACGTGTGCATAGAGGTGGTCTTAATGTAGGTCTTAACTTTATACTTAGCAAGTTACTC CATCCCAATTTAGTGCTCCTGTGTGACCTTCGCCCTGTGTCCTTCCATTTCCTGTCTTTC CCGTCCATCACCCATCCTAAGCACTTACGTGAGTAAATAATGCAGCTCAGATGCTGAGCT CTAGTAGGAAATGCTGGCATGCTGATTACAAGATACAGCTGAGCAATGCACACATTTTCA GCTGGGAGTTTCTGTTCTCTGGCAAATTCTTCACTGAGTCTGGAACAATAATACCCTATG ATTAGAACTGGGGAAACAGAACTGAATTGCTGTGTTATATGAGGAATTAAAACCTTCAAA TCTCTATTTCCCCCAAATACTGACCCATTCTGGACTTTTGTAAACATACCTAGGCCCCTG TTCCCCTGAGAGGGTGCTAAGAGGAAGGATGAAGGGCTTCAGGCTGGGGGCAGTGGACAG GGAATTGGGATACCTGGATTCTGGTTCTGACAGGGCCACAAGCTAGGATCTCTAACAAAC GCAGAAGGCTTTGGCTCGTCATTTCCTCTTAAAAAGGAGGAGCTGGGCTTCAGCTCTAAG AACTTCATTGCCCTGGGGATCAGACAGCCCCTACCTACCCCTGCCCACTCCTCTGGAGAC TGAGCCTTGCCCGTGCATATTTAGGTCATTTCCCACACTGTCTTAGAGAACTTGTCACCA GAAACCACATGTATTTGCATGTTTTTTGTTAATTTAGCTAAAGCAATTGAATGTAGATAC TCAGAAGAAATAAAAAATGATGTTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_003240 unedited
GGGNNCGGCCGCGCAATTCCCGGGATCTGAGACCCTCCTTCAACCTCCCTAGAGACAGCC CCACTCTGCCTCCTGCTCCCCCAGGGCAGCACCATGTGGCCCCTGTGGCTCTGCTGGGCA CTCTGGGTGCTGCCCCTGGCTGGCCCCGGGGCGGCCCTGACCGAGGAGCAGCTCCTGGGC AGCCTGCTGCGGCAGCTGCAGCTCAGCGAGGTGCCCGTACTGGACAGGGCCGACATGGAG AAGCTGGTCATCCCCGCCCACGTGAGGGCCCAGTATGTAGTCCTGCTGCGGCGCAGCCAC GGGGACCGCTCCCGCGGAAAGAGGTTCAGCCAGAGCTTCCGAGAGGTGGCCGGCAGGTTC CTGGCGTCGGAGGCCAGCACACACCTGCTGGTGTTCGGCATGGAGCAGCGGCTGCCGCCC AACAGCGAGCTGGTGCAGGCCGTGCTGCGGCTCTTCCAGGAGCCGGTCCCCAAGGCCGCG CTGCACAGGCACGGGCGGCTGTCCCCGCGCAGCGCCCAGGCCCGGGTGACCGTCGAGTGG CTGCGCGTCCGCGACGACGGCTCCAACCGCACCTCCCTCATCGACTCCAGGCTGGTGTCC GTCCACGAGAGCGGCTGGGAAGCCTTCGACGTGACCGAGGCCGTGAACTTCTGGCAGCAA CTGAGCCCGCCCCGGCAGCCGCTGCTGCTACAGGTGTCGGTGCAGAGGGAGCATCTGGGC CCGCTGGCGTCCGGCGCCCACAAGCTGGTCCGCTTTGGCCTCGCAAGGGGCGCCAGCCGG GGCTTGGGGAGCCCCAACTGGAGCTGCACACCCTGGACCTCAGGGACTATGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_003240 |
| Insert Size | 2090 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003240.2, NP_003231.2 |
| RefSeq Size | 2102 bp |
| RefSeq ORF | 1101 bp |
| Locus ID | 7044 |
| UniProt ID | O00292 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | TGF-beta signaling pathway |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207799 | LEFTY2 (Myc-DDK-tagged)-Human left-right determination factor 2 (LEFTY2), transcript variant 1 |
CNY 3,656.00 |
|
| RC207799L3 | Lenti ORF clone of Human left-right determination factor 2 (LEFTY2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207799L4 | Lenti ORF clone of Human left-right determination factor 2 (LEFTY2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG207799 | LEFTY2 (tGFP-tagged) - Human left-right determination factor 2 (LEFTY2), transcript variant 1 |
CNY 4,370.00 |
