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Nkx2.5 (NKX2-5) (NM_004387) Human Untagged Clone
CAT＃: SC122678
NKX2 (untagged)-Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CHNG5; CSX; CSX1; HLHS2; NKX2.5; NKX2E; NKX4-1; VSD3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004387 edited
GACGGGTGCGCGGGCGGGCGGCGGCACCATGCAGGGAAGCTGCCAGGGGCCGTGGGCAGC GCCGCTTTCTGCCGCCCACCTGGCGCTGTGAGACTGGCGCTGCCACCATGTTCCCCAGCC CTGCTCTCACGCCCACGCCCTTCTCAGTCAAAGACATCCTAAACCTGGAACAGCAGCAGC GCAGCCTGGCTGCCGCCGGAGAGCTCTCTGCCCGCCTGGAGGCGACCCTGGCGCCCTCCT CCTGCATGCTGGCCGCCTTCAAGCCAGAGGCCTACGCTGGGCCCGAGGCGGCTGCGCCGG GCCTCCCAGAGCTGCGCGCAGAGCTGGGCCGCGCGCCTTCACCGGCCAAGTGTGCGTCTG CCTTTCCCGCCGCCCCCGCCTTCTATCCACGTGCCTACAGCGACCCCGACCCAGCCAAGG ACCCTAGAGCCGAAAAGAAAGAGCTGTGCGCGCTGCAGAAGGCGGTGGAGCTGGAGAAGA CAGAGGCGGACAACGCGGAGCGGCCCCGGGCGCGACGGCGGAGGAAGCCGCGCGTGCTCT TCTCGCAGGCGCAGGTCTATGAGCTGGAGCGGCGCTTCAAGCAGCAGCGGTACCTGTCGG CCCCCGAACGCGACCAGCTGGCCAGCGTGCTGAAACTCACGTCCACGCAGGTCAAGATCT GGTTCCAGAACCGGCGCTACAAGTGCAAGCGGCAGCGGCAGGACCAGACTCTGGAGCTGG TGGGGCTGCCCCCGCCGCCGCCGCCGCCTGCCCGCAGGATCGCGGTGCCAGTGCTGGTGC GCGATGGCAAGCCATGCCTAGGGGACTCGGCGCCCTACGCGCCTGCCTACGGCGTGGGCC TCAATCCCTACGGTTATAACGCCTACCCCGCCTATCCGGGTTACGGCGGCGCGGCCTGCA GCCCTGGCTACAGCTGCACTGCCGCTTACCCCGCCGGGCCTTCCCCAGCGCAGCCGGCCA CTGCCGCCGCCAACAACAACTTCGTGAACTTCGGCGTCGGGGACTTGAATGCGGTTCAGA GCCCCGGGATTCCGCAGAGCAACTCGGGAGTGTCCACGCTGCATGGTATCCGAGCCTGGT AGGGAAGGGACCCGCGTGGCGCGACCCTGACCGATCCCACCTCAACAGCTCCCTGACTCT CGGGGGGAGAAGGGGCTCCCAACATGACCCTGAGTCCCCTGGATTTTGCATTCACTCCTG CGGAGACCTAGGAACTTTTTCTGTCCCACGCGCGTTTGTTCTTGCGCACGGGAGAGTTTG TGGCGGCGATTATGCAGCGTGCAATGAGTGATCCTGCAGCCTGGTGTCTTAGCTGTCCCC CCAGGAGTGCCCTCCGAGAGTCCATGGGCACCCCCGGTTGGAACTGGGACTGAGCTCGGG CACGCAGGGCCTGAGATCTGGCCGCCCATTCCGCGAGCCAGGGCCGGGCGCCCGGGCCTT TGCTATCTCGCCGTCGCCCGCCCACGCACCCACCCGTATTTATGTTTTTACCTATTGCTG TAAGAAATGACGATCCCCTTCCCATTAAAGAGAGTGCGTTGAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAA >OriGene 5' read for NM_004387 unedited
NGCGGTTCAGATTTTGTAATACGACTTATTATAGGGCGGCCGCGATTCCCGGGATGACGG GTGCGCGGGCGGGCGGCGGCACCATGCAGGGAAGCTGCCAGGGGCCGTGGGCAGCGCCGC TTTCTGCCGCCCACCTGGCGCTGTGAGACTGGCGCTGCCACCATGTTCCCCAGCCCTGCT CTCACGCCCACGCCCTTCTCAGTCAAAGACATCCTAAACCTGGAACAGCAGCAGCGCAGC CTGGCTGCCGCCGGAGAGCTCTCTGCCCGCCTGGAGGCGACCCTGGCGCCCTCCTCCTGC ATGCTGGCCGCCTTCAAGCCAGAGGCCTACGCTGGGCCCGAGGCGGCTGCGCCGGGCCTC CCAGAGCTGCGCGCAGAGCTGGGCCGCGCGCCTTCACCGGCCAAGTGTGCGTCTGCCTTT CCCGCCGCCCCCGCCTTCTATCCACGTGCCTACAGCGACCCCGACCCAGCCAAGGACCCT AGAGCCGAAAAGAAAGAGCTGTGCGCGCTGCAGAAGGCGGTGGAGCTGGAGAAGACAGAG GCGGACAACGCGGAGCGGCCCCGGGCGCGACGGCGGAGGAAGCCGCGCGTGCTCTTCTCG CAGGCGCANGTCTATGAGCTGGAGCGGCGCTTCAAGCAGCAGCGGTACCTGTCGGCCCCC GAACGCGACCAGCTGGCCAGCGTGCTGAAACTCACGTCCACGCAGGTCAAGATCTGGTTC CAGAACCCGCGCTANCAGTGCAAGCGGCAGCGGCAGGACCAGACTCTGGAGCTGGGGGGG CTGCCCCGNCGGCGCGGCGCCTGCCCGNAGATCGCGGTGCAGTGCTGTGCGCGATGGCAG CCATGCCTAGGGACTCGGCGCCTACCGCCTGCTACGCGTGGGCCTCAATCCTACG >OriGene 3' read for NM_004387 unedited
GGACATTCTTCCCCTTTATAGGGNAAGGGTTCCGTNCATTTCTTACAGCAATAGGGTAAA AACATAAATACGGGTGGGTGCGTGGGCGGGCGACGGCGAAGAAGCAAAGGCCCGGGCGCC CGGCCCTGGCTCGCGGAATGGGCGGCCAGATCTCAGGCCCTGCGTGCCCGAGCTCAGTCC CAGTTCCAACCGGGGGTGCCCATGGACTCTCGGAGGGCACTCCTGGGGGGACAGCTAAGA CACCAGGCTGCAGGATCACTCATTGCACGCTGCATAATCGCCGCCACAAACTCTCCCGTG CGCAAGAACAAACGCGCGTGGGACAGAAAAAGTTCCTAGGTCTCCGCAGGAGTGAATGCA AAATCCAGGGGACTCAGGGTCATGTTGGGAGCCCCTTCTCCCCCCGAGAGTCAGGGAGCT GTTGAGGTGGGATCGGTCAGGGTCGCGCCACGCGGGTCCCTTCCCTACCAGGCTCGGATA CCATGCAGCGTGGACACTCCCGAGTTGCTCTGCGGAATCCCGGGGCTCTGAACCGCATTC AAGTCCCCGACGCCGAAGTTCACGAAGTTGTTGTTGGCGGCGGCAGTGGCCGGCTGCGCT GGGGAAGGCCCGGCGGGGTAAGCGGCAGTGCAGCTGTAGCCAGGGCTGCAGGCCGCGCCG CCGTAACCCGGATAGGCGGGGTAGGCGTTATAACCGTAGGGATTGAGGCCCACGCCGTAA GCAGGCGCGTAGGGCGCCGAGTCCCCTAGGCATGGCTTGCCATCGCGCACAACACTGGCA CCGCGATCCTGCGGCAAGCGGCGGCCGCCGGCGGGGCAACCCCCCCCGCTCCAGAATCTG GTCCTGGCGCTGCCGCTTGACTTGTACGCCCGGTTCTGGACCAGATCTTGACCCGCGTGG ACCTGAATTTAACAAACTGGCCACTTGGTG |
| Restriction Sites | Please inquire |
| ACCN | NM_004387 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004387.2, NP_004378.1 |
| RefSeq Size | 1585 bp |
| RefSeq ORF | 975 bp |
| Locus ID | 1482 |
| UniProt ID | P52952 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Transcript Variant: This variant (1) represents the shortest transcript but encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Deciphering Transcriptional Networks during Human Cardiac Development
,null,
Cells
,PubMed ID 36497174
[NKX2-5]
|
|
Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome
,null,
PLoS ONE
,PubMed ID 25050861
[NKX2-5]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206550 | NKX2 (Myc-DDK-tagged)-Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1 |
CNY 2,400.00 |
|
| RC206550L1 | Lenti ORF clone of Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC206550L2 | Lenti ORF clone of Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206550L3 | Lenti ORF clone of Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206550L4 | Lenti ORF clone of Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG206550 | NKX2 (tGFP-tagged) - Human NK2 transcription factor related, locus 5 (Drosophila) (NKX2-5), transcript variant 1 |
CNY 4,000.00 |
