beta TRCP2 (FBXW11) (NM_033645) Human Untagged Clone
CAT＃: SC125348
FBXW11 (untagged)-Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1
CNY 3792.00
CNY 8080.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BTRC2; BTRCP2; FBW1B; Fbw11; FBXW1B; Hos; NEDJED |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_033645 edited
GAATTCGGCACGAGGCGGCGGCCCGGGCGGGCTGGCAGCTAGAGTGGGTGCGATAGCCGC CTCCGCCTCTGCCGCCTCCGCCGTCGCCTCCTCCGCCCGGGCCGTTCGCTGCTGCGCGGG GAGAGCGAGGCGGGGCCGCCGGGGCCGCCATGGAGCCCGACTCGGTGATTGAGGACAAGA CCATCGAGCTCATGATAAGTAATGGAACATCATCTGTGATCGTCTCCAGAAAGAGGCCAT CAGAAGGAAACTATCAAAAAGAAAAAGACTTGTGTATTAAATATTTTGACCAGTGGTCTG AATCAGATCAAGTGGAATTTGTGGAACATCTTATTTCACGAATGTGTCATTATCAGCATG GACATATTAACTCTTACCTGAAGCCCATGTTGCAGCGGGACTTTATTACCGCTTTACCAG AGCAAGGCTTAGATCACATAGCAGAAAACATTCTTTCGTACCTGGATGCCAGGTCTCTGT GTGCAGCAGAGCTGGTATGTAAAGAATGGCAGCGAGTGATCTCAGAAGGAATGCTTTGGA AGAAGCTGATTGAACGAATGGTACGCACTGATCCCCTATGGAAAGGACTTTCAGAAAGAA GAGGGTGGGATCAGTACCTGTTTAAAAACAGACCCACAGATGGCCCTCCAAATTCATTTT ATAGGTCATTATACCCAAAGATTATCCAGGATATAGAGACTATAGAATCTAACTGGCGGT GTGGACGACACAACTTGCAGAGGATTCAGTGCCGCTCTGAAAATAGTAAAGGTGTCTACT GTTTACAGTACGATGATGAAAAAATTATCAGTGGCCTACGAGATAATTCTATTAAGATAT GGGATAAAACCAGCCTGGAATGTTTGAAAGTGTTAACAGGACACACAGGCTCTGTCCTCT GTCTGCAGTATGATGAGCGTGTCATTGTAACTGGCTCTTCAGATTCTACGGTGAGAGTGT GGGATGTGAACACGGGTGAAGTTCTTAACACATTGATCCACCACAATGAGGCTGTATTGC ACTTACGCTTCAGCAATGGACTGATGGTGACCTGTTCCAAGGACCGCTCCATTGCTGTGT GGGACATGGCTTCTGCGACCGACATCACTTTACGCCGTGTCCTGGTTGGCCACCGGGCTG CCGTCAATGTAGTAGACTTTGACGACAAGTACATCGTGTCTGCCTCTGGTGACAGGACCA TCAAAGTCTGGAGCACGAGCACCTGTGAATTTGTTCGTACTCTCAATGGGCACAAGCGGG GCATTGCCTGTCTCCAGTACAGGGATCGCCTGGTTGTTAGTGGATCATCAGATAATACCA TTAGGCTCTGGGATATTGAATGTGGTGCCTGTTTAAGAGTCCTAGAGGGACATGAAGAAT TGGTCCGATGCATCCGGTTTGATAACAAGAGGATTGTCAGTGGGGCCTATGATGGGAAAA TTAAAGTTTGGGACTTGCAAGCTGCTCTTGACCCTCGAGCCCCAGCAAGCACATTGTGTT TGCGCACATTGGTGGAACATTCTGGACGTGTGTTTCGGCTCCAGTTTGATGAGTTTCAGA TCATCAGCAGCTCCCATGATGACACTATTTTGATTTGGGATTTCTTAAATGTGCCTCCCA GTGCCCAGAATGAGACCCGTTCTCCCTCCAGAACATACACTTACATCTCTAGATAACAGT CTGCACTTTCACCCGTTTCAGGGTTTTCTAGTCTTGAACTACTGGCTACGTGGCTACCAA ATGCCTAAGGGAGTTCGTTCACAGCTGAGTTATGAAGCTGGAATTGGTTCTAGACGCTGG GTAGATGCAAAGCAGCCTAACTCTTCAAGTACCGACATTTCTCACCTCTGATTCCGGCTC TCCTTTGAGAAGGAGACCTTAGCTTCCCCGGCTTCAAGTAGAACAGAAGCCCGTTTCCTT CCCTCATCAGTGAAAAAATCTAATGTTTCAAATGTAAATTGTTCATAGAAAAGGAACATA GAATCTGTTTTACAGAAGTAAATCGACCGTCAAGAGAAGACTTGGCCTCTAATTTATATT GCTTTGCACTTTGGTTTGATATTAAGAAACAGCATTCTTCTTCAGTGAAATTTTGGGTGC CAAACACCTACCCAGAATGTCCAGGGCTTTCATTTTCAAAAGTTAGCATTCTCCTTTTGA CCGTCCAAGTCATTATGAATTCTGACTTGTTGTATTAGGAACATGTTGGACAGTGGAAAA TTTTCTCTGGATTGTTTTAGTAATATTTTTGGGATTATACTTCCTTTCTGTACCAATTTC TTTTAATTTAAAGAACTATAAGTCAGTTATATTATCTACCAACAGGTAATATAGCTCTTT CTTTTATTAACTGTTCTCTGTCCCCCAACCATCTCCTGATATTTGGTAGAGTAACACCTT TATACGTGTGCTTGCCTCCTAATTTAAAATACTGTATTCGCATGTAGATATAATGTACAT AACAGTTTAACCTCAAAGTTGCTGGAGTCAGGGCCCCCTGTGCTTGAGACACTAATACAG AGTGTGTTCGCACTTAGCCATGGGCTXXXXXXXXXXXXXXXXXXXXXXXXXXXTGCCCTT CGCCATTGTTTCCAAAGATCAAGGAATGTCAATAACATTTTAAAGGACCAATAAACAGCC TCCTATAAAGTAAACCTCTTCCCGTGGAAGCACACTCTACTACTAAAGGGAAGGCCCCTG GGCTCTGATTTGTCCTTTGCATTGAGAACGGTGTGGGGATCAGTGTGTGTGTATGTGATT TGTTTATTGAGTTGGCTTTGCTTTTTTAGTTTTTCTTTTAAAAATAAAATCCTTCCTTCC CATGTTACTAAATTAATTTATGTTTTTGAGAGGTTGAGTCTCAAAGTGTAAACAATAAAC CTCCATTCATAAGGTGGATGTTGTAAGCTTGATGGTGGTTGTGAAAGTGATTTAGCTTTG ACCACTTTTCATCCTACAGCTTCAATATCAAACTGGTTAGGAAAGCCCAGGGGGAAGGGA GGGGGCAGGGGAGGAGGCAATTCTGAATGAATGAATGGATTTTTTGTTGTTTTTGCATGT TTAATATAGAAGTTCCCCTCGTTCCTTGGGAGATGATGGCCTTTGAATATGCAGACAACC TTTGAATTGTGCCTACTAAATTATAGCAGGGGACTTTGGCACCCAAGGAGTTCTGACTTT CTGGGATTATAATAGTAATTCCCAGCCATACTCTGGACTTTATTTTGCTAACCATAACTG AGCAAATGTAAATTACTGCTATATTAATGTTTTAAAGCACTGGGATAGTCTAATTCTAAC TTGTAATTAATTATGTTTGCCAATTATCTGTTTGAAATAAATTTGTGTCTGAACAGCTAT TGAAACTGTTAAATTGTACAGATATTATTCATGACAGCTTTGTACTGTGGAATGTGCTTA ATAAAAAACAAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_033645 unedited
ACTATAGGGCGGCCGCGATTCGGCACGAGGCGGCGGCCCGGGCGGGCTGGCAGCTAGAGT GGGTGCGATAGCCGCCTCCGCCTCTGCCGCCTCCGCCGTCGCCTCCTCCGCCCGGGCCGT TCGCTGCTGCGCGGGGAGAGCGAGGCGGGGCCGCCGGGGCCGCCATGGAGCCCGACTCGG TGATTGAGGACAAGACCATCGAGCTCATGATAAGTAATGGAACATCATCTGTGATCGTCT CCAGAAAGAGGCCATCAGAAGGAAACTATCAAAAAGAAAAAGACTTGTGTATTAAATATT TTGACCAGTGGTCTGAATCAGATCAAGTGGAATTTGTGGAACATCTTATTTCACGAATGT GTCATTATCAGCATGGACATATTAACTCTTACCTGAAGCCCATGTTGCAGCGGGACTTTA TTACCGCTTTACCAGAGCAAGGCTTAGATCACATAGCAGAAAACATTCTTTCGTACCTGG ATGCCAGGTCTCTGTGTGCAGCAGAGCTGGTATGTAAAGAATGGCAGCGAGTGATCTCAG AAGGAATGCTTTGGAAGAAGCTGATTGAACGAATGGTACGCACTGATCCCCTATGGAAAG GACTTTCAGAAAGAAGAGGGTGGGATCAGTACCTGTTTAAAAACAGACCCACAGATGGCC CTCCAAATTCATTNTATAGGTCATTATACCCAAAGATTATCCAGGATATAGAGACTATAG AATCTACTGGCGGTGTGGACGACACAACTTGCAGAGGATTCAGTGCCGCTCTGAAATAGT AAAGGTGTCTACTGTNTACAGTACGATGATGAANAAATTATCAGTGGCCTACGAGATATT CTATTAGATATGGGATAAAACANCCTGAATGTTTGAAAGG >OriGene 3' read for NM_033645 unedited
GTTTTTTTTGTGGGCACTTTCCACAGTACAAANCTGTCATGNATAATATCTGTACAATTT AACAGTTTCAATAGCTGTTCAGACACAAATTTATTTCAAACAGATAATTGGCAAACATAA TTAATTACAAGTTAGAATTAGACTATCCCAGTGCTTTAAAACATTAATATAGCAGTAATT TACATTTGCTCAGTTATGGTTAGCAAAATAAAGTCCAGAGTATGGCTGGGAATTACTATT ATAATCCCAGAAAGTCAGAACTCCTTGGGTGCCAAAGTCCCCTGCTATAATTTAGTAGGC ACAATTCAAAGGTTGTCTGCATATTCAAAGGCCATCATCTCCCAAGGAACGAGGGGAACT TCTATATTAAACATGCAAAAACAACAAAAAATCCATTCATTCATTCAGAATTGCCTCCTC CCCTGCCCCCTCCCTTCCCCCTGGGCTTTCCTAACCAGTTTGATATTGAAGCTGTAGGAT GAAAAGTGGTCAAAGCTAAATCACTTTCACAACCACCATCAAGCTTACAACATCCACCTT ATGAATGGAGGTTTATTGTTTACACTTTGAGACTCAACCTCTCANAAACATAAATTAATT TAGTAACATGGGAAGGAAGGATTTTATTTTTAAAAGAAAAACTAAAAAAGCAAAGCCAAC TCAATANACAAATCACATACACACACACTGATCCCCACACCGTTCTCAATGCAAAGGACA AATCAGAGCCCAGGGGCCCTTCCCTTTAGTAGTAGAGTGTGCCTCCACGGGAAGAATTTT ACTTTATAGGAAGCTGTTTATTGGTCCCTTTAAAAGTTATTGACATTCCCTTGATCTTTG AAAACAATGGCGAAAGGGCAATCAAACCTAATTTTGGAATAAGGGGAGAAAGGATGGCCA ATTGGATGCCCAACGGTCTTTCCATGGCCTTTTCAAGGGCACCGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_033645 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033645.2, NP_387449.2 |
| RefSeq Size | 4473 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 23291 |
| UniProt ID | Q9UKB1 |
| Domains | WD40, F-box |
| Protein Families | Druggable Genome |
| Protein Pathways | Hedgehog signaling pathway, Oocyte meiosis, Ubiquitin mediated proteolysis, Wnt signaling pathway |
| Gene Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) lacks an exon in the 5' coding region, compared to variant 3, and encodes a shorter isoform (A), compared to isoform C. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221110 | FBXW11 (Myc-DDK-tagged)-Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1 |
CNY 3784.00 |
|
| RC221110L1 | Lenti ORF clone of Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1, Myc-DDK-tagged |
CNY 6184.00 |
|
| RC221110L2 | Lenti ORF clone of Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1, mGFP tagged |
CNY 6370.00 |
|
| RC221110L3 | Lenti ORF clone of Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1, Myc-DDK-tagged |
CNY 6370.00 |
|
| RC221110L4 | Lenti ORF clone of Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1, mGFP tagged |
CNY 6370.00 |
|
| RG221110 | FBXW11 (tGFP-tagged) - Human F-box and WD repeat domain containing 11 (FBXW11), transcript variant 1 |
CNY 4940.00 |
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