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PIAS2 (NM_004671) Human Untagged Clone
CAT＃: SC125358
PIAS2 (untagged)-Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta
CNY 4,632.00
CNY 9,980.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARIP3; DIP; MIZ1; PIASX; SIZ2; ZMIZ4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125358 sequence for NM_004671 edited (data generated by NextGen Sequencing)
ATGGCGGATTTCGAAGAGTTGAGGAATATGGTTTCTAGTTTTAGGGTTTCTGAACTACAA GTATTACTAGGCTTTGCTGGACGGAATAAAAGTGGACGCAAGCATGACCTCCTGATGAGG GCGCTGCATTTATTGAAGAGCGGCTGCAGCCCTGCGGTTCAGATTAAAATCCGAGAATTG TATAGACGCCGATATCCACGAACTCTTGAAGGACTTTCTGATTTATCCACAATCAAATCA TCGGTTTTCAGTTTGGATGGTGGCTCATCACCTGTAGAACCTGACTTGGCCGTGGCTGGA ATCCACTCGTTGCCTTCCACTTCAGTTACACCTCACTCACCATCCTCTCCTGTTGGTTCT GTGCTGCTTCAAGATACTAAGCCCACATTTGAGATGCAGCAGCCATCTCCCCCAATTCCT CCTGTCCATCCTGATGTGCAGTTAAAAAATCTGCCCTTTTATGATGTCCTTGATGTTCTC ATCAAGCCCACGAGTTTAGTTCAAAGCAGTATTCAGCGATTTCAAGAGAAGTTTTTTATT TTTGCTTTGACACCTCAACAAGTTAGAGAGATATGCATATCCAGGGATTTTTTGCCAGGT GGTAGGAGAGATTATACAGTCCAAGTTCAGTTGAGACTTTGCCTGGCAGAGACAAGTTGC CCTCAAGAAGATAACTATCCAAATAGTCTATGTATAAAAGTAAATGGGAAGCTATTTCCT TTGCCTGGCTATGCACCACCGCCTAAAAATGGGATTGAACAGAAGCGCCCTGGACGCCCC TTGAATATTACATCTTTAGTTAGGTTATCTTCAGCTGTGCCAAACCAAATTTCCATTTCT TGGGCATCAGAAATTGGGAAGAATTACTCTATGTCTGTATATCTTGTACGGCAGCTTACA TCAGCCATGTTATTACAGAGATTAAAAATGAAAGGTATTAGAAACCCTGATCATTCCAGA GCACTAATTAAAGAAAAACTTACTGCAGATCCTGATAGTGAAATTGCTACAACTAGCCTT CGGGTATCCTTGATGTGCCCTTTAGGAAAAATGAGGCTGACAATCCCATGCCGTGCAGTG ACTTGTACACATCTGCAGTGTTTTGATGCTGCCCTCTATCTACAAATGAATGAGAAAAAG CCCACCTGGATTTGTCCTGTGTGTGACAAAAAAGCTGCCTATGAAAGTCTAATATTAGAT GGGCTTTTTATGGAAATTCTCAATGACTGTTCTGATGTAGATGAGATCAAATTCCAAGAA GATGGTTCTTGGTGTCCAATGAGACCGAAGAAAGAAGCTATGAAAGTATCCAGCCAACCG TGTACAAAAATAGAAAGTTCAAGCGTCCTCAGTAAGCCTTGTTCAGTGACTGTAGCCAGT GAGGCAAGCAAGAAGAAAGTAGATGTTATTGATCTTACAATAGAAAGCTCTTCTGACGAA GAGGAAGACCCTCCTGCCAAAAGGAAATGCATCTTTATGTCAGAAACACAAAGCAGCCCA ACCAAAGGGGTTCTCATGTATCAGCCATCTTCTGTAAGGGTGCCCAGTGTGACTTCGGTT GATCCTGCTGCTATTCCGCCTTCATTAACAGACTACTCAGTACCATTCCACCATACGCCA ATATCAAGCATGTCATCAGATTTGCCAGGTTTGGATTTTCTTTCCCTTATTCCAGTTGAT CCCCAGTACTGTCCTCCTATGTTTTTGGATAGTCTCACCTCACCCTTAACAGCAAGCAGT ACGTCTGTCACCACCACCAGCTCCCATGAAAGCAGTACTCATGTTAGTTCATCCAGCAGC AGGAGTGAGACAGGGGTCATAACCAGCAGTGGAAGTAACATTCCTGACATCATCTCATTG GACTAA Clone variation with respect to NM_004671.3 >OriGene 5' read for NM_004671 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGGCGGCGGCCGCG GCGTCTTAAGCGGCGCCCAGTGCAGGATGGTGCTGGAGGCGGCGGCGGCCGTGGTGGCGG CAGCGTCGTTGGCGGCAGCGGGAGTGGGTGCGGCGGCAGCGGCGGCGGCGCCCGCGGGTG GTATAAAATGGCGGATTTCGAAGAGTTGAGGAATATGGTTTCTAGTTTTAGGGTTTCTGA ACTACAAGTATTACTAGGCTTTGCTGGACGGAATAAAAGTGGACGCAAGCATGACCTCCT GATGAGGGCGCTGCATTTATTGAAGAGCGGCTGCAGCCCTGCGGTTCAGATTAAAATCCG AGAATTGTATAGACGCCGATATCCACGAACTCTTGAAGGACTTTCTGATTTATCCACAAT CAAATCATCGGTTTTCAGTTTGGATGGTGGCTCATCACCTGTAGAACCTGACTTGGCCGT GGCTGGAATCCACTCGTTGCCTTCCACTTCAGTTACACCTCACTCACCATCCTCTNCTGT TGGTTCTGTGCTGCTTCAAGATACTAAGCCCACATTTGAGATGCAGCAGCCATCTCCCCC AATTCCTCCTGTCCATCCTGATGTGCAGTTAAAAAATCTGCCCTTTTATGATGTCCTTGA TGTTCTCATCAAGCCCACGAGTTTAGTTCANAGCAGTATTCAGCGATTTAAAGAGAAGTT NTTTATTNTTGCTTTGACACCTCAAACAGTTAGAGAGATATGCATATCCAGNNGATTTTT TGCCANNGTGGTANNGAGAGATTATACAGTCCAAGTTCAGTTGAGACTTTGCCTGGCAGA GACAAGTTGCCCTCAAGAAGATNACTATCCCAATAGTCTATGTATAAAAAAGTAATGGAA GCTATTTCCTTTGCCTGGCTATGACCCACCGCCTAAANATGG >OriGene 3' read for NM_004671 unedited
NAAAGACATTCTCATCTTGTACTTCANNTGCTCTTTATTTAACAAAACTTTTTTCACTGA TTTGTAGACTCCATCCATTAACGTATGAAAGTGAAATCCATCTCTCAGGAAGATACAGTT ATGGTTGAATGTATCTGATGCTGAGAGTACAGCATAATTAAAAAAAATCCTTGCCTGTCA TTTTGGTTTCTTGTTGCGAGTCTTTTGGGGTTTCCCCCTCTCAAAAAGCCAAAAAACCCC TTTTGGGTTTCTTTGAAATTCCCCCCCTTTTTTTAAAACAAAAAAAAAAAAAACCTTTTC CCCCCAGTTATTCTCCTCCCACAAAAGTCTCCTTCTTGGATAATAATTCCCCCACCACAC GGGGGGGCCCCCTTTCTCTCTCAAAAAAATTTTATTCGACTGGGAGAATTTTCCCCCTCT TTCTTTTTTTCCTACCCCTCTTCTTTTCCCCTCCCGTGTTTTTCGTTAGACAACATCCTC CCCCTCTTCTCTCACTTCACTCCCGCATGCTCGGCCCCGCTTATCACCGTCTTCCTTTTC ATTTCCGGCGGAATCGGCCCCCTTCCCCCCCCACCCGTTTTATCCCCGTCCCCCTAGTTT CCCCCTCTCTGTATCATGTCGGCCTCTTCTTCCCCTTCCCCCTACATTCCTATTCCCCCC GCTGTTCTTCCCTATATTTCACCTCCTTTTCCGTTTCCTCATCCTTTTTTCATCTTCTCT CCATTTCGCCTTTTGTTCTCGCCCTCGTCTCACTGTTTTCCGTCCCTTCTCTCCTTTTTC TACACGTGCCTACTTCCTCGTTGTCCCCACTCTCGCCCCCCTTTCTTTTCCCCTTCTTGT TCGTTCGGTGCCCCGCTTTTTTTTCTCCCCATGCTCCCTTTTGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004671 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004671.2, NP_004662.2 |
| RefSeq Size | 2360 bp |
| RefSeq ORF | 1866 bp |
| Locus ID | 9063 |
| UniProt ID | O75928 |
| Domains | SAP, zf-MIZ |
| Protein Families | Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis |
| Gene Summary | This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (beta) encodes isoform (beta). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212659 | PIAS2 (Myc-DDK-tagged)-Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta |
CNY 4,560.00 |
|
| RC212659L1 | Lenti ORF clone of Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC212659L2 | Lenti ORF clone of Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta, mGFP tagged |
CNY 6,460.00 |
|
| RC212659L3 | Lenti ORF clone of Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC212659L4 | Lenti ORF clone of Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta, mGFP tagged |
CNY 6,460.00 |
|
| RG212659 | PIAS2 (tGFP-tagged) - Human protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta |
CNY 5,040.00 |
