DYNLT1 (NM_006519) Human Untagged Clone

CAT#: SC126752

DYNLT1 (untagged)-Human dynein, light chain, Tctex-type 1 (DYNLT1)



  "NM_006519" in other vectors (6)

CNY 1,800.00


货期*
现货

规格
    • 10 ug

Product images

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DYNLT1 Rabbit polyclonal Antibody
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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CW-1; TCTEL1; tctex-1; TCTEX1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC126752 sequence for NM_006519 edited (data generated by NextGen Sequencing)
ATGGAAGACTACCAGGCTGCGGAGGAGACTGCTTTTGTTGTTGATGAAGTGAGCAACATT
GTAAAAGAGGCTATAGAAAGCGCAATTGGTGGTAACGCTTATCAACACAGCAAAGTGAAC
CAGTGGACCACAAATGTAGTAGAACAAACTTTAAGCCAACTCACCAAGCTGGGAAAACCA
TTTAAATACATCGTGACCTGTGTAATTATGCAGAAGAATGGAGCTGGATTACACACAGCA
AGTTCCTGCTTCTGGGACAGCTCTACTGACGGGAGCTGCACTGTGCGATGGGAGAATAAG
ACCATGTACTGCATCGTCAGTGCCTTCGGACTGTCTATTTGA

Clone variation with respect to NM_006519.2
>OriGene 5' read for NM_006519 unedited
CCCCCCCCCCGCCCCCCCCCCCCCTCCCCCGGTTTAGATTTGNATACGACTCATATAGGC
GGCCGCGNAATTCGCACCGACGCGCCGGNAGNAAAGATGGAAGACTACCAGGCTGCGGAG
GAGACTGCTTTTGTTGTTGATGAAGTGAGCAACATTGTAAAAGAGGCTATAGAAAGCGCA
ATTGGTGGTAACGCTTATCAACACAGCAAAGTGAACCAGTGGACCACAAATGTAGTAGAA
CAAACTTTAAGCCAACTCACCAAGCTGGGAAAACCATTTAAATACATCGTGACCTGTGTA
ATTATGCAGAAGAATGGAGCTGGATTACACACAGCAAGTTCCTGCTTCTGGGACAGCTCT
ACTGACGGGAGCTGCACTGTGCGATGGGAGAATAAGACCATGTACTGCATCGTCAGTGCC
TTCGGACTGTCTATTTGACCTGCAGTCCAGCCTATGGCCTTTCTCCTTTTGTCTCTAGTT
CATCCTCTAACCACCAGCCATGAATTCAGTGAACTCTTTTCTCATTCTCTTTGTTTTGNG
GCACTTTCACAATGTAGAGGAAAAAACCAAATGACCGCACTGTGATGTGAATGGCACCGA
AGTCAGATGAGTATCCCCTGTAGGTCACCTGCAGCCTGCGTTGCCACTTGTCTTAACTCT
GAATATTTCATTTCAAAGGTGCTAAAATCTGAAATCTGCTAGTGTGAAACTTGCTCTACT
CTCTGAAATGATTCACATACACTAATTTTCCATACTTTATACTTTTGTTAGAATANATTA
TTCANATCTAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGT
TTCCTTGACAGATCCCGGGTTGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCT
TGAAGTTGCCCCTCCAGTGCCCACCAGCCTTGTCCTAATAAAATAAGNTGCATCATT
Restriction Sites NotI-NotI     
ACCN NM_006519
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_006519.1, NP_006510.1
RefSeq Size 713 bp
RefSeq ORF 342 bp
Locus ID 6993
UniProt ID P63172
Domains Tctex-1
Gene Summary This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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