MSL2L1 (MSL2) (NM_018133) Human Untagged Clone
CAT＃: SC127078
MSL2 (untagged)-Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1
CNY 4304.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MSL-2; MSL2L1; RNF184 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127078 sequence for NM_018133 edited (data generated by NextGen Sequencing)
ATGAACCCCGTGAATGCTACTGCTCTCTACATTTCCGCGAGCCGCCTAGTGCTCAACTAC GACCCCGGAGACCCCAAGGCGTTTACTGAGATTAACAGGCTCTTGCCTTACTTCCGACAG TCCCTTTCGTGCTGTGTTTGCGGACATTTGCTACAAGATCCTATTGCACCCACCAACTCC ACCTGCCAACATTATGTCTGCAAAACTTGTAAAGGCAAGAAAATGATGATGAAACCTTCC TGTAGCTGGTGCAAAGACTATGAGCAGTTTGAGGAAAACAAGCAGTTAAGCATCCTAGTG AACTGCTACAAAAAACTATGCGAGTATATAACACAGACTACACTGGCACGGGATATAATA GAAGCAGTTGACTGTTCTTCTGATATTTTGGCTTTGCTTAATGATGGATCATTGTTTTGT GAGGAGACAGAAAAACCCTCAGATTCATCCTTTACTTTGTGTTTGACACATTCCCCTTTA CCTTCAACCTCAGAACCCACAACTGATCCTCAAGCTAGTTTATCTCCAATGTCTGAAAGC ACCCTCAGCATTGCTATTGGCAGTTCTGTTATCAATGGTTTGCCTACTTATAATGGGCTT TCAATAGATAGATTTGGTATAAATATTCCTTCACCTGAACATTCAAATACGATTGACGTA TGTAATACTGTTGACATAAAAACTGAGGATCTGTCTGACAGCCTGCCACCCGTTTGTGAC ACAGTAGCCACTGACTTATGTTCCACAGGCATTGATATCTGCAGTTTCAGTGAAGATATA AAACCTGGAGACTCTCTGTTACTGAGTGTTGAGGAAGTACTCCGCAGCTTAGAAACTGTT TCAAATACAGAGGTCTGTTGCCCTAATTTGCAGCCGAACTTGGAAGCCACTGTATCCAAT GGACCTTTTCTGCAGCTTTCTTCCCAGTCTCTTAGCCATAATGTTTTTATGTCCACCAGT CCTGCACTTCATGGGTTATCATGTACAGCAGCAACTCCGAAGATAGCAAAATTGAATAGA AAACGATCCAGATCAGAGAGTGACAGTGAGAAAGTTCAGCCACTTCCAATTTCTACCATT ATCCGAGGCCCAACACTGGGGGCATCTGCTCCTGTGACAGTGAAACGGGAGAGCAAAATT TCTCTTCAACCTATAGCAACTGTTCCCAATGGAGGCACAACACCTAAAATCAGCAAAACT GTACTTTTATCTACTAAAAGCATGAAAAAGAGTCATGAACATGGATCCAAGAAATCTCAC TCTAAAACCAAGCCAGGTATTCTTAAAAAAGACAAAGCAGTAAAGGAAAAGATTCCTAGT CATCATTTTATGCCAGGAAGTCCTACCAAGACTGTGTACAAAAAACCCCAGGAAAAGAAA GGGTGTAAATGTGGGCGTGCTACTCAAAATCCAAGTGTTCTTACATGCCGAGGCCAACGC TGCCCTTGCTACTCTAACCGCAAAGCCTGCTTAGATTGTATATGTCGTGGCTGCCAAAAC TCCTATATGGCCAATGGGGAGAAGAAGCTGGAGGCATTTGCCGTGCCAGAAAAGGCCTTG GAGCAGACCAGGCTCACTTTGGGCATTAACGTGACTAGCATTGCTGTGCGTAACGCTAGT ACCAGCACCAGTGTAATAAATGTCACAGGGTCCCCAGTAACGACGTTTTTAGCTGCCAGT ACACATGATGATAAAAGTTTGGATGAAGCTATAGACATGAGATTCGACTGTTAA Clone variation with respect to NM_018133.3 >OriGene 5' read for NM_018133 unedited
GGGGTTCACAATTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGCAAACTT GCACGGATTTTGGTTACTTGTTTGGCCAATGGTTCGGCTCTGATTTCTTCCGAATTGTTG CAAATTCGCCATCGTTCCCTGGCTGCTTACTAAGTTGGATCCGGAATTTCTTTTCAACCG GGAGCCATTGGTGTCGAAGTGTCTGCAATGAACCCCGTGAATGCTACTGCTCTCTACATT TCCGCGAGCCGCCTAGTGCTCAACTACGACCCCGGAGACCCCAAGGCGTTTACTGAGATT AACAGGCTCTTGCCTTACTTCCGACAGTCCCTTTCGTGCTGTGTTTGCGGACATTTGCTA CAAGATCCTATTGCACCCACCAACTCCACCTGCCAACATTATGTCTGCAAAACTTGTAAA GGCAAGAAAATGATGATGAAACCTTCCTGTAGCTGGTGCAAAGACTATGAGCAGTTTGAG GAAAACAAGCAGTTAAGCATCCTAGTGAACTGCTACAAAAAACTATGCGAGTATATAACA CAGACTACACTGGCACGGGATATAATAGAAGCAGTTGACTGTTCTTCTGATATTTTGGCT TTGCTTAATGATGGATCATTGTTTTGTGAGGAGACAGAAAAACCCTCAGATTCATCCTTT ACTTTGTGTTTGACACATTCCCCTTTACCTTCAACCTCAGAACCCACAACTGATCCTCAA GCTAGTTTATCTCCAATGTCTGAAAGCACCCTCAGCATTGCTATTGGCAGTTCTGTTATC AATGGTTTGCCTACTTATAATGGGCTNTCAATAGATAGATTTGGTATAAATATTCCTTCA CCTGAACATTCAAATACGATTGACGTATGTAATACTGTTGACATAAAAACTNGAGATCTG TCTGACAGCCTGNCACCCCGTTGT >OriGene 3' read for NM_018133 unedited
NGGGTATTCTATGNACCGCGCCGCATTCTANGATCGATTTTTTTTTTTTTTTTTTTTTCA TTTTCCACCATTTACTCTTGTTATCAAAAAAGTTCAACTCTTCTTGCAAAACAAAAACAA AATAGTACATACTGGACACATACATCACATTTTTCTTCCTATGGCTTTAGCCCACCCCCA CCCCACCAAAAGAGACCAAAAAAAAAAAAAGAAAAAAAAGCCCAACAACAACAACAAAAA CAACTCTACCTGACCACATTCACAGAAAATGACACCAGGATACACTACAAAACAGAAGGA GGTGTCATCTGCTCTGTGTCCAAAGGTTTCTTCTCCATGTCTTGTACTAGGCGAGTAACC ATCATTGAACATGCTGTGTGCCAAATCAAAACATAACTTCAGCATATGTCAGATCTTACT AGAGATGGTGAACGTAGTAGAAATTGGAAATTTTCCAGCAGTATTTTTCTTTAAATAAGC ACTGTCAAAGCTGCAGCTCTTCTTTTAAATCACAGGTTATTTCATTACACCTAGTCAGTC CTTGTTTTATTTGGGCTGTGCTCTTTCAAGCAACTGACTAGATTTCCCTTCAACAGAATG TTTGTGACTCACTTGTCTTCCCCATAAAAATTAACCGGAAGAAGTGCATTTAAACTGAAA CATACTTTGTGCTTTACATGCAAAAGAGCATTCTAAAGAAAATCCTCCTAGCTTCAACCT ACCTAAATGCACAGGCTTTATAAAAAGGCATTNCTATTAGGCCTCTATAAAGAAGCCTTC ATATGAACAGCACCCTAAAAAAACTAGGAGCATATTCAAAATAAGACTGTGGCANATAAC TATTAGAGAAATAGTCAAGTGGCGGGCAGTGGGCATAGTACATACACAATCTGGGCAGTC TGGAGCATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018133 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018133.2, NP_060603.2 |
| RefSeq Size | 4696 bp |
| RefSeq ORF | 1734 bp |
| Locus ID | 55167 |
| UniProt ID | Q9HCI7 |
| Protein Families | Druggable Genome |
| Gene Summary | Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210829 | MSL2 (Myc-DDK-tagged)-Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1 |
CNY 4296.00 |
|
| RC210829L1 | Lenti ORF clone of Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1, Myc-DDK-tagged |
CNY 6696.00 |
|
| RC210829L2 | Lenti ORF clone of Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RC210829L3 | Lenti ORF clone of Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC210829L4 | Lenti ORF clone of Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RG210829 | MSL2 (tGFP-tagged) - Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1 |
CNY 5896.00 |
