KCNQ3 (NM_004519) Human Untagged Clone
CAT＃: SC303492
KCNQ3 (untagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1
CNY 6392.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BFNC2; EBN2; KV7.3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004519 edited
GCGGATCATGGCATTGGAGTTCCCGGGCTTGCAGCCGCCGCCGCCGCCTCGTTCACGCAC CCCGAGCGCCCCTTCTTCCCAGAGCAGCAGCGGAGAAGGCGAAGCGGCCGGCGGGGGCGA GGCAGATGGGGCTCAAGGCGCGCAGGGCGGCGGGGGCGGCTGGCGGCGGCGGCGACGGGG GCGGCGGAGGCGGCGGGGCGGCTAACCCAGCCGGAGGGGACGCGGCGGCGGCCGGCGACG AGGAGCGGAAAGTGGGGCTGGCGCCCGGCGACGTGGAGCAAGTCACCTTGGCGCTCGGGG CCGGAGCCGACAAAGACGGGACCCTGCTGCTGGAGGGCGGCGGCCGCGACGAGGGGCAGC GGAGGACCCCGCAGGGCATCGGGCTCCTGGCCAAGACCCCGCTGAGCCGCCCAGTCAAGA GAAACAACGCCAAGTACCGGCGCATCCAAACTTTGATCTACGACGCCCTGGAGAGACCGC GGGGCTGGGCGCTGCTTTACCACGCGTTGGTGTTCCTGATTGTCCTGGGGTGCTTGATTC TGGCTGTCCTGACCACATTCAAGGAGTATGAGACTGTCTCGGGAGACTGGCTTCTGTTAC TGGAGACATTTGCTATTTTCATCTTTGGAGCCGAGTTTGCTTTGAGGATCTGGGCTGCTG GATGTTGCTGCCGATACAAAGGCTGGCGGGGCCGACTGAAGTTTGCCAGGAAGCCCCTGT GCATGTTGGACATCTTTGTGCTGATTGCCTCTGTGCCAGTGGTTGCTGTGGGAAACCAAG GCAATGTTCTGGCCACCTCCCTGCGAAGCCTGCGCTTCCTGCAGATCCTGCGCATGCTGC GGATGGACCGGAGAGGTGGCACCTGGAAGCTTCTGGGCTCAGCCATCTGTGCCCACAGCA AAGAACTCATCACGGCCTGGTACATCGGTTTCCTGACACTCATCCTTTCTTCATTTCTTG TCTACCTGGTTGAGAAAGACGTCCCAGAGGTGGATGCACAAGGAGAGGAGATGAAAGAGG AGTTTGAGACCTATGCAGATGCCCTGTGGTGGGGCCTGATCACACTGGCCACCATTGGCT ATGGAGACAAGACACCCAAAACGTGGGAAGGCCGTCTGATTGCCGCCACCTTTTCCTTAA TTGGCGTCTCCTTTTTTGCCCTTCCAGCGGGCATCCTGGGGTCCGGGCTGGCCCTCAAGG TGCAGGAGCAACACCGTCAGAAGCACTTTGAGAAAAGGAGGAAGCCAGCTGCTGAGCTCA TTCAGGCTGCCTGGAGGTATTATGCTACCAACCCCAACAGGATTGACCTGGTGGCGACAT GGAGATTTTATGAATCAGTCGTCTCTTTTCCTTTCTTCAGGAAAGAACAGCTGGAGGCAG CATCCAGCCAAAAGCTGGGTCTCTTGGATCGGGTTCGCCTTTCTAATCCTCGTGGTAGCA ATACTAAAGGAAAGCTATTTACCCCTCTGAATGTAGATGCCATAGAAGAAAGTCCTTCTA AAGAACCAAAGCCTGTTGGCTTAAACAATAAAGAGCGTTTCCGCACGGCCTTCCGCATGA AAGCCTACGCTTTCTGGCAGAGTTCTGAAGATGCCGGGACAGGTGACCCCATGGCGGAAG ACAGGGGCTATGGGAATGACTTCCCCATCGAAGACATGATCCCCACCCTGAAGGCCGCCA TCCGAGCCGTCAGAATTCTACAATTCCGTCTCTATAAAAAAAAATTCAAGGAGACTTTGA GGCCTTACGATGTGAAGGATGTGATTGAGCAGTATTCTGCCGGGCATCTCGACATGCTTT CCAGGATAAAGTACCTTCAGACGAGAATAGATATGATTTTCACCCCTGGACCTCCCTCCA CGCCAAAACACAAGAAGTCTCAGAAAGGGTCAGCATTCACCTTCCCATCCCAGCAATCTC CCAGGAATGAACCATATGTAGCCAGACCATCCACATCAGAAATCGAAGACCAAAGCATGA TGGGGAAGTTTGTAAAAGTTGAAAGACAGGTTCAGGACATGGGGAAGAAGCTGGACTTCC TCGTGGATATGCACATGCAACACATGGAACGGTTGCAGGTGCAGGTCACGGAGTATTACC CAACCAAGGGCACCTCCTCGCCAGCTGAAGCAGAGAAGAAGGAGGACAACAGGTATTCCG ATTTGAAAACCATCATCTGCAACTATTCTGAGACAGGCCCCCCGGAACCACCCTACAGCT TCCACCAGGTGACCATTGACAAAGTCAGCCCCTATGGGTTTTTTGCACATGACCCTGTGA ACCTGCCCCGAGGGGGACCCAGTTCTGGAAAGGTTCAGGCAACTCCTCCTTCCTCAGCAA CAACGTATGTGGAGAGGCCCACGGTCCTGCCTATCTTGACTCTTCTCGACTCCCGAGTGA GCTGCCACTCCCAGGCTGACCTGCAGGGCCCCTACTCGGACCGAATCTCCCCCCGGCAGA GACGTAGCATCACGCGAGACAGTGACACACCTCTGTCCCTGATGTCGGTCAACCACGAGG AGCTGGAGAGGTCTCCAAGTGGCTTCAGCATCTCCCAGGACAGAGATGATTATGTGTTCG GCCCCAATGGGGGGTCGAGCTGGATGAGGGAGAAGCGGTACCTCGCCGAGGGTGAGACGG ACACAGACACGGACCCCTTCACGCCCAGCGGCTCCATGCCTCTGTCGTCCACAGGGGATG GGATTTCTGATTCAGTATGGACCCCTTCCAATAAGCCCATTTAAAAGAGGTCACTGGCTG ACCCCTCCTTGTAATGTAGACAGACTTTGTATAGTTCACTTACTCTTACACCCGACGCTT ACCAGCGGGGACACCAATGGCTGCATCAAATGCATGCGTGTGCGTGGTGGCCCCACCCAG GCAGGGGCTTCCCACAGCCTCTTCCTCCCCATGTCACCACAACAAAGTGCTTCCTTTTCA GCATGGTTTGCATGACTTTACACTATATAAATGGTTCCGCTAATCTCTTCTAGGATAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004519 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004519.2, NP_004510.1 |
| RefSeq Size | 3097 bp |
| RefSeq ORF | 2619 bp |
| Locus ID | 3786 |
| UniProt ID | O43525 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). The 5' extent of this variant is inferred based on orthologous alignments. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218739 | KCNQ3 (Myc-DDK-tagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1 |
CNY 6384.00 |
|
| RC218739L1 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, Myc-DDK-tagged |
CNY 8784.00 |
|
| RC218739L2 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, mGFP tagged |
CNY 11120.00 |
|
| RC218739L3 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, Myc-DDK-tagged |
CNY 11120.00 |
|
| RC218739L4 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1, mGFP tagged |
CNY 11120.00 |
|
| RG218739 | KCNQ3 (tGFP-tagged) - Human potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 1 |
CNY 10170.00 |
