gp340 (DMBT1) (NM_007329) Human Untagged Clone
CAT＃: SC303910
DMBT1 (untagged)-Human deleted in malignant brain tumors 1 (DMBT1), transcript variant 2
CNY 46460.00
货期*
8周
规格
Product images
推荐一起购买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GP340; muclin; SAG; SALSA |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_007329, the custom clone sequence may differ by one or more nucleotides
ATGGGGATCTCCACAGTCATCCTTGAAATGTGTCTTTTATGGGGACAAGTTCTATCTACA GGTGGGTGGATCCCAAGGACTACAGACTACGCTTCACTGATTCCCTCGGAGGTGCCCTTG GATCCAACTGTAGCAGAAGGTTCTCCATTTCCCTCGGAGTCGACCCTGGAGTCAACTGTA GCAGAAGGTTCTCCGATTTCCTTGGAGTCAACCCTGGAGTCAACCGTAGCAGAAGGTTCT CTGATTCCCTCAGAGTCAACCCTGGAGTCAACTGTAGCAGAAGGATCTGATTCTGGTTTG GCCCTGAGGCTGGTGAATGGAGATGGCAGGTGTCAGGGCCGAGTGGAGATCCTATACCGA GGCTCCTGGGGCACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAACGTGGTCTGT AGGCAGCTGGGTTGTGGCTGGGCCATGTCAGCTCCAGGAAATGCCTGGTTTGGCCAGGGC TCAGGACCCATTGCCCTGGATGATGTGCGCTGCTCAGGACACGAATCCTACCTGTGGAGC TGCCCCCACAATGGCTGGCTCTCCCATAACTGTGGCCATGGTGAAGATGCTGGTGTTATC TGCTCAGCTGCCCAGCCTCAGTCAACACTCAGGCCAGAAAGTTGGCCTGTCAGGATATCA CCACCTGTACCCACAGAAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGC GACAGGTGTCGAGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGAT GACTACTGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCC ATGTCAGCCCCAGGAAATGCCCAGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGAT GTGCGCTGCTCAGGACATGAGTCCTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCACC CACAACTGTGGCCATAGTGAAGACGCTGGTGTCATCTGCTCAGCTCCCCAGTCCCGGCCG ACACCCAGCCCAGATACTTGGCCGACCTCACATGCATCAACAGCAGGACCTGAATCCAGT TTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATAC CGAGGCTCCTGGGGCACCGTGTGTGATGATAGCTGGGACACCAGTGACGCCAATGTGGTC TGCCGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGCCAG GGTTCAGGACCCATTGTCCTGGATGACGTGCGCTGCTCAGGCTATGAGTCCTACCTGTGG AGCTGCCCCCACAATGGCTGGCTCTCCCATAACTGTCAGCACAGTGAAGACGCTGGTGTC ATCTGCTCAGCTGCCCACTCCTGGTCGACGCCCAGTCCAGACACGTTGCCGACCATCACC TTACCTGCATCGACAGTAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGT GACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGAT GACAGCTGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCC ATGTTGGCCCCAGGAAATGCCCGGTTTGGTCAGGGCTCAGGACCCATTGTCCTGGATGAC GTGCGCTGCTCAGGGAATGAGTCCTACTTGTGGAGCTGCCCCCACAATGGCTGGCTCTCC CATAACTGTGGCCATAGTGAAGACGCTGGTGTCATCTGCTCAGGACCTGAATCCAGTTTG GCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCGA GGCTCTTGGGGCACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAATGTGGTCTGC AGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGTCAGGGC TCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGACATGAGTCCTACCTGTGGAGC TGCCCCAACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGATGCTGGTGTCATC TGCTCAGCTGCCCAGTCCCGGTCGACGCCCAGGCCAGACACGTTGTCGACCATCACGTTA CCTCCATCGACAGTAGGATCTGAATCCAGTTTGACCCTGAGGCTGGTGAATGGAAGTGAC AGGTGTCAGGGCCGAGTAGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGAC AGCTGGGATACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCCACG TCGGCCCCAGGAAATGCCCGGTTTGGCCAGGGCTCAGGACCCATTGTTCTGGATGATGTG CGCTGCTCAGGACACGAGTCCTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCAC AACTGTGGCCATCATGAAGATGCTGGTGTCATCTGCTCAGTTTCCCAGTCCCGGCCGACA CCCAGTCCAGATACTTGGCCGACCTCACATGCATCAACAGCAGGACCTGAATCCAGTTTG GCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCGA GGCTCCTGGGGCACCGTGTGTGATGATAGCTGGGACACCAGTGACGCCAATGTGGTCTGC CGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGCCAGGGT TCAGGACCCATTGTCCTGGATGACGTGCGCTGCTCAGGCTATGAGTCCTACCTGTGGAGC TGCCCCCACAATGGCTGGCTCTCCCATAACTGTCAGCACAGTGAAGACGCTGGTGTCATC TGCTCAGCTGCCCACTCCTGGTCGACGCCCAGTCCAGACACATTGCCGACCATCACCTTG CCTGCATCGACAGTAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGAC AGGTGTCAGGGCCGAGTGGAGGTCCTATACCAAGGCTCCTGGGGCACCGTGTGCGATGAC AGCTGGGACACCAATGATGCCAATGTCGTCTGCAGGCAACTGGGCTGTGGCTGGGCCATG TCAGCCCCAGGAAATGCCCGGTTTGGTCAGGGCTCAGGACCCATTGTCCTGGATGATGTG CGCTGCTCAGGACACGAGTCTTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCAC AACTGTGGCCATAGTGAAGACGCTGGTGTCATCTGCTCAGCTTCCCAGTCCCGGCCAACA CCTAGTCCAGACACTTGGCCAACCTCACATGCATCAACAGCAGGATCTGAATCCAGTTTG GCCCTGAGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCGA GGCTCCTGGGGCACCGTGTGTGATGACTACTGGGACACCAATGATGCCAATGTGGTTTGC AGGCAGCTGGGCTGTGGCTGGGCCATGTCAGCCCCAGGAAATGCCCGGTTTGGCCAGGGT TCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGACATGAGTCCTATCTGTGGAGC TGCCCCCACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGACGCTGGTGTCATC TGCTCAGCTTCCCAGTCCCAGCCGACACCCAGCCCAGACACTTGGCCAACCTCACATGCA TCAACAGCAGGATCTGAATCCAGTTTGGCCCTGAGGCTGGTGAATGGAGGTGACAGGTGT CAGGGCCGAGTGGAGGTCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGACTACTGG GACACCAATGATGCCAATGTGGTTTGCAGGCAGCTGGGCTGTGGCTGGGCCACGTCAGCC CCAGGAAATGCCCGGTTTGGCCAGGGTTCAGGACCCATTGTCCTGGATGATGTGCGCTGC TCAGGACATGAGTCCTATCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCACAACTGT GGCCATCATGAAGACGCTGGTGTCATCTGCTCAGCTTCCCAGTCCCAGCCGACACCCAGC CCAGACACTTGGCCAACCTCACATGCATCAACAGCAGGATCTGAATCCAGTTTGGCCCTG AGGCTGGTGAATGGAGGTGACAGGTGTCAGGGCCGAGTGGAGGTCCTATACCGAGGCTCC TGGGGCACCGTGTGTGATGACTACTGGGACACCAATGATGCCAATGTGGTTTGCAGGCAG CTGGGCTGTGGCTGGGCCACGTCAGCCCCAGGAAATGCCCGGTTTGGCCAGGGTTCAGGA CCCATTGTCCTGGATGATGTGCGCTGCTCAGGACATGAGTCCTATCTGTGGAGCTGCCCC CACAATGGCTGGCTCTCCCACAACTGTGGCCATCATGAAGACGCTGGTGTCATCTGCTCA GCTTCCCAGTCCCAGCCGACACCCAGCCCAGACACTTGGCCAACCTCTCGTGCATCAACA GCAGGATCTGAATCCACTTTGGCCCTGAGACTGGTGAATGGAGGTGACAGGTGTCGAGGC CGAGTGGAGGTCCTATACCAAGGCTCCTGGGGCACCGTGTGTGATGACTACTGGGACACC AATGATGCCAACGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCCATGTCAGCCCCAGGA AATGCCCAGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGA CACGAGTCTTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCACAACTGTGGCCAT CATGAAGATGCTGGTGTCATCTGCTCAGCTGCTCAGTCCCAGTCAACGCCCAGGCCAGAT ACTTGGCTGACCACCAACTTACCGGCATTGACAGTAGGATCTGAATCCAGTTTGGCTCTG AGGCTGGTGAATGGAGGTGACAGGTGTCGAGGCCGAGTGGAGGTCCTGTATCGAGGCTCC TGGGGAACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAATGTGGTCTGCAGGCAG CTGGGCTGTGGCTGGGCCATGTCGGCCCCAGGAAATGCCCGGTTTGGCCAGGGCTCAGGA CCCATTGTCCTGGATGATGTGCGCTGCTCAGGGAATGAGTCCTACCTGTGGAGCTGCCCC CACAAAGGCTGGCTCACCCACAACTGTGGCCATCACGAAGACGCTGGTGTCATCTGCTCA GCCACCCAAATAAATTCTACTACGACAGATTGGTGGCATCCAACAACTACAACCACTGCA AGACCCTCTTCAAATTGTGGTGGCTTCTTATTCTATGCCAGTGGGACATTCTCCAGCCCA TCCTACCCTGCATACTACCCCAACAATGCTAAGTGTGTTTGGGAAATAGAAGTGAATTCT GGTTATCGCATAAACCTGGGCTTCAGTAATCTGAAATTGGAGGCACACCATAACTGCAGT TTTGATTATGTTGAAATCTTTGATGGATCATTGAATAGCAGTCTCCTGCTGGGGAAAATC TGTAATGATACCAGGCAAATATTTACATCTTCTTACAACCGAATGACCATTCACTTTCGA AGTGACATCAGTTTCCAAAACACTGGCTTTTTGGCTTGGTATAACTCCTTCCCAAGCGAT GCCACCTTGAGGTTGGTCAATTTAAATTCATCCTATGGTCTATGTGCCGGGCGTGTAGAA ATTTACCATGGTGGCACCTGGGGGACAGTTTGTGATGACTCCTGGACCATTCAGGAAGCT GAGGTGGTCTGCAGACAGCTAGGGTGTGGACGTGCAGTTTCAGCCCTTGGAAATGCATAT TTTGGCTCTGGCTCTGGCCCCATCACCCTGGACGATGTAGAGTGCTCAGGGACGGAATCC ACTCTCTGGCAGTGCCGGAACCGAGGCTGGTTCTCCCACAACTGTAATCATCGTGAAGAT GCTGGTGTCATCTGCTCAGGAAACCATCTATCGACACCTGCTCCTTTTCTCAACATCACC CGTCCAAACACAGATTATTCCTGCGGAGGCTTCCTATCCCAACCATCAGGGGACTTTTCC AGCCCATTCTATCCCGGGAACTATCCAAACAATGCCAAGTGTGTGTGGGACATTGAGGTG CAAAACAACTACCGTGTGACTGTGATCTTCAGAGATGTCCAGCTTGAAGGTGGCTGCAAC TATGATTATATTGAAGTTTTCGATGGCCCCTACCGCAGTTCCCCTCTCATTGCTCGAGTT TGTGATGGGGCCAGAGGCTCCTTCACTTCTTCCTCCAACTTCATGTCCATTCGCTTCATC AGTGACCACAGCATCACAAGGAGAGGGTTCCGGGCTGAGTACTACTCCAGTCCCTCCAAT GACAGCACCAACCTGCTCTGTCTGCCAAATCACATGCAAGCCAGTGTGAGCAGGAGCTAT CTCCAATCCTTGGGCTTTTCTGCCAGTGACCTTGTCATTTCCACCTGGAATGGATACTAC GAGTGTCGGCCCCAGATAACGCCGAACCTGGTGATATTCACAATTCCCTACTCAGGCTGC GGCACCTTCAAGCAGGCAGACAATGACACCATCGACTATTCCAACTTCCTCACAGCAGCT GTCTCAGGTGGCATCATCAAGAGGAGGACAGACCTCCGTATTCACGTCAGCTGCAGAATG CTTCAGAACACCTGGGTCGACACCATGTACATTGCTAATGACACCATCCACGTTGCTAAT AACACCATCCAGGTCGAGGAAGTCCAGTATGGCAATTTTGACGTGAACATTTCCTTTTAT ACTTCCTCATCTTTCTTGTATCCTGTGACCAGCCGCCCTTACTACGTGGACCTGAACCAG GACTTGTACGTTCAGGCTGAAATCCTCCATTCTGATGCTGTACTGACCTTGTTTGTGGAC ACCTGCGTGGCATCACCATACTCCAATGACTTCACGTCTTTGACTTATGATCTAATCCGG AGTGGATGCGTGAGGGATGACACCTACGGACCCTACTCCTCGCCATCTCTTCGCATTGCC CGCTTCCGGTTCAGGGCCTTCCACTTCCTGAACCGCTTCCCCTCCGTGTACCTGCGTTGT AAAATGGTGGTGTGCAGAGCGTATGACCCCTCTTCCCGCTGCTACCGAGGCTGTGTGTTG AGGTCGAAGAGGGATGTGGGCTCCTACCAGGAAAAGGTGGACGTCGTCCTGGGTCCCATC CAGCTGCAGACCCCCCCACGCCGAGAAGAGGAGCCTCGGTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_007329 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007329.1, NP_015568.1 |
| RefSeq Size | 7686 bp |
| RefSeq ORF | 7242 bp |
| Locus ID | 1755 |
| UniProt ID | Q9UGM3 |
| Protein Families | Druggable Genome |
| Gene Summary | Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (2) encodes the longest isoform (b). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Customer
Reviews
Loading...
