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IL19 (NM_013371) Human Untagged Clone
CAT＃: SC304003
IL19 (untagged)-Human interleukin 19 (IL19), transcript variant 2
CNY 2,400.00
CNY 3,990.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IL-10C; MDA1; NG.1; ZMDA1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_013371 edited
ATTTCCTCTTATCCACCTGAATAAAAATGACCAGCCCTTTCCAAATGGCAGAGAGCACTG AGAGGAGACACAAGGAGCAGCCCGCAAGCACCAAGTGAGAGGCATGAAGTTACAGTGTGT TTCCCTTTGGCTCCTGGGTACAATACTGATATTGTGCTCAGTAGACAACCACGGTCTCAG GAGATGTCTGATTTCCACAGACATGCACCATATAGAAGAGAGTTTCCAAGAAATCAAAAG AGCCATCCAAGCTAAGGACACCTTCCCAAATGTCACTATCCTGTCCACATTGGAGACTCT GCAGATCATTAAGCCCTTAGATGTGTGCTGCGTGACCAAGAACCTCCTGGCGTTCTACGT GGACAGGGTGTTCAAGGATCATCAGGAGCCAAACCCCAAAATCTTGAGAAAAATCAGCAG CATTGCCAACTCTTTCCTCTACATGCAGAAAACTCTGCGGCAATGTCAGGAACAGAGGCA GTGTCACTGCAGGCAGGAAGCCACCAATGCCACCAGAGTCATCCATGACAACTATGATCA GCTGGAGGTCCACGCTGCTGCCATTAAATCCCTGGGAGAGCTCGACGTCTTTCTAGCCTG GATTAATAAGAATCATGAAGTAATGTTCTCAGCTTGATGACAAGGAACCTGTATAGTGAT CCAGGGATGAACACCCCCTGTGCGGTTTACTGTGGGAGACAGCCCAC >OriGene 5' read for NM_013371 unedited
NAGGTCACATTTGTATACGACTCATATAGGGCGGCCGCGATTCAAATCTGGTACCGAGCT CGGATCCACTAGTAACGGCCGCCAGTGTGCTGGAATTCGCCCTTAGCATTTCCTCTTATC CACCTGAATAAAAATGACCAGCCCTTTCCAAATGGCAGAGAGCACTGAGAGGAGACACAA GGAGCAGCCCGCAAGCACCAAGTGAGAGGCATGAAGTTACAGTGTGTTTCCCTTTGGCTC CTGGGTACAATACTGATATTGTGCTCAGTAGACAACCACGGTCTCAGGAGATGTCTGATT TCCACAGACATGCACCATATAGAAGAGAGTTTCCAAGAAATCAAAAGAGCCATCCAAGCT AAGGACACCTTCCCAAATGTCACTATCCTGTCCACATTGGAGACTCTGCAGATCATTAAG CCCTTAGATGTGTGCTGCGTGACCAAGAACCTCCTGGCGTTCTACGTGGACAGGGTGTTC AAGGATCATCAGGAGCCAAACCCCAAAATCTTGAGAAAAATCAGCAGCATTGCCAACTCT TTCCTCTACATGCAGAAAACTCTGCGGCAATGTCAGGAACAGAGGCAGTGTCACTGCAGG CAGGAAGCCACCAATGCCACCAGAGTCATCCATGACAACTATGATCAGCTGGAGGTCCAC GCTGCTGCCATTAAATCCCTGGGAGAGCTCGACGTCTTTCTAGCCTGGATTAATAAGAAT CATGAAGTAATGTTCTCAGCTTGATGACAAGGAACCTGTATAGTGATCCAGGGATGAACA CCCNCTGTGCGGTTTACTGTGGGAGACAGCCCACAGGGGCGAATTCTGCAGATATCCATC ACACTGGGCGGCCGCTCGACTCTAGATTGCNGGCCGCGTCATAGCTGTTTCCCTGACAC |
| Restriction Sites | Please inquire |
| ACCN | NM_013371 |
| Insert Size | 700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This construct is a cloned PCR fragment that was fully sequenced. There are no nucleotide differences between the OriGene clone and the NCBI reference ORF. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_013371.2, NP_037503.2 |
| RefSeq Size | 1831 bp |
| RefSeq ORF | 534 bp |
| Locus ID | 29949 |
| UniProt ID | Q9UHD0 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
| Gene Summary | The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains two alternate 5' non-coding exons, resulting in translation initiation from an in-frame downstream AUG start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Expression and Suppressive Effects of Interleukin-19 on Vascular Smooth Muscle Cell Pathophysiology and Development of Intimal Hyperplasia
,Ying Tian, Laura J. Sommerville, Anthony Cuneo, Sheri E. Kelemen, and Michael V. Autieri,
Am. J. Pathol., Sep 2008; 173: 901 - 909.
[IL19]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212571 | IL19 (Myc-DDK-tagged)-Human interleukin 19 (IL19), transcript variant 2 |
CNY 2,400.00 |
|
| RC212571L1 | Lenti ORF clone of Human interleukin 19 (IL19), transcript variant 2, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC212571L2 | Lenti ORF clone of Human interleukin 19 (IL19), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC212571L3 | Lenti ORF clone of Human interleukin 19 (IL19), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212571L4 | Lenti ORF clone of Human interleukin 19 (IL19), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG212571 | IL19 (tGFP-tagged) - Human interleukin 19 (IL19), transcript variant 2 |
CNY 4,000.00 |
