FISH (SH3PXD2A) (NM_014631) Human Untagged Clone
CAT＃: SC304145
SH3PXD2A (untagged)-Human SH3 and PX domains 2A (SH3PXD2A)
CNY 21380.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FISH; SH3MD1; TKS5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC304145 representing NM_014631.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCTCGCCTACTGCGTGCAGGATGCCACCGTGGTGGACGTGGAGAAGCGGAGGAACCCCTCCAAGCAC TACGTATACATAATCAATGTGACCTGGTCTGACTCCACCTCCCAGACTATCTACCGGAGGTACAGCAAG TTCTTTGACCTGCAGATGCAGCTTTTGGATAAGTTTCCCATTGAAGGTGGCCAGAAGGACCCCAAGCAA AGGATCATCCCCTTCCTCCCAGGCAAGATCCTCTTCCGCAGAAGCCACATCCGGGACGTAGCTGTGAAG AGACTGAAGCCCATCGATGAATACTGCCGGGCACTTGTCCGGCTGCCCCCCCACATCTCACAGTGTGAC GAAGTCTTCCGGTTCTTCGAGGCTCGACCCGAGGATGTCAACCCTCCAAAAGAGGACTATGGCAGTTCC AAGAGGAAATCAGTGTGGCTGTCCAGCTGGGCTGAGTCGCCCAAGAAGGACGTGACAGGTGCCGACGCC ACCGCCGAGCCCATGATCCTGGAACAGTACGTGGTGGTGTCCAACTATAAGAAGCAGGAGAACTCGGAG CTGAGCCTCCAGGCCGGGGAGGTGGTGGATGTCATCGAGAAGAACGAGAGCGGCTGGTGGTTCGTGAGC ACTTCTGAGGAGCAGGGCTGGGTCCCTGCCACCTACCTGGAGGCCCAGAATGGTACTCGGGATGACTCC GACATCAACACCTCTAAGACTGGAGAAGAGGAGAAGTATGTCACCGTGCAGCCTTACACCAGCCAAAGC AAGGACGAGATTGGCTTTGAGAAGGGCGTCACAGTGGAGGTGATCCGGAAGAATCTGGAAGGCTGGTGG TATATCAGATACCTGGGCAAAGAGGGCTGGGCGCCAGCATCCTACCTGAAGAAGGCCAAGGATGACCTG CCAACCCGGAAGAAGAACCTGGCCGGCCCAGTGGAGATCATTGGGAACATCATGGAGATCAGCAACCTG CTGAACAAGAAGGCGTCTGGGGACAAGGAAACTCCACCAGCCGAAGGCGAGGGCCATGAGGCCCCCATT GCCAAGAAGGAGATCAGCCTGCCCATCCTCTGCAATGCCTCCAATGGCAGTGCCGTGGGCGTTCCTGAC AGGACTGTCTCCAGGCTGGCCCAGGGCTCTCCAGCTGTGGCCAGGATTGCCCCTCAGCGGGCCCAGATC AGCTCCCCGAACCTACGGACAAGACCTCCACCACGCAGAGAATCCAGCCTGGGGTTCCAACTGCCAAAG CCACCAGAGCCCCCTTCTGTTGAGGTGGAGTACTACACCATTGCCGAATTCCAGTCGTGCATTTCCGAT GGCATCAGCTTTCGGGGTGGACAGAAGGCAGAGGTCATTGATAAGAACTCAGGTGGCTGGTGGTACGTG CAGATCGGTGAGAAGGAGGGCTGGGCCCCCGCATCATACATCGATAAGCGCAAGAAGCCCAACCTGAGC CGCCGCACAAGCACGCTGACCCGGCCCAAGGTGCCCCCGCCAGCACCCCCCAGCAAGCCCAAGGAGGCC GAGGAGGGCCCTACGGGGGCCAGTGAGAGCCAGGACTCCCCGCGGAAGCTCAAGTATGAGGAGCCTGAG TATGACATCCCTGCATTCGGCTTTGACTCAGAGCCTGAGCTGAGCGAGGAGCCCGTGGAGGACAGAGCC TCAGGGGAGAGGCGGCCTGCCCAGCCCCACCGGCCCTCGCCGGCCTCTTCTCTGCAGCGGGCCCGCTTC AAGGTGGGTGAGTCTTCAGAGGATGTGGCCCTGGAAGAGGAGACCATCTATGAGAATGAGGGCTTCCGG CCATATGCAGAGGACACCCTGTCAGCCAGAGGCTCCTCCGGGGACAGCGACTCCCCAGGCAGCTCCTCG CTGTCCCTGACCAGGAAAAACTCCCCCAAATCAGGCTCCCCCAAGTCATCATCACTCCTAAAGCTCAAG GCAGAGAAGAATGCCCAGGCAGAAATGGGGAAGAACCACTCCTCAGCCTCCTTTTCCTCATCCATCACC ATCAACACCACTTGCTGCTCCTCCTCTTCCTCCTCCTCCTCTTCCTTGTCCAAAACCAGTGGCGACCTG AAGCCCCGCTCTGCTTCGGACGCAGGCATCCGCGGCACTCCCAAGGTCAGGGCAAAGAAGGATGCTGAT GCGAACGCTGGGCTGACCTCCTGTCCCCGGGCCAAGCCATCGGTCCGGCCCAAGCCATTCCTAAACCGA GCAGAGTCGCAGAGCCAAGAGAAGATGGACATCAGCACTTTACGGCGCCAGCTGAGACCCACAGGCCAG CTCCGTGGAGGGCTCAAGGGCTCCAAGAGTGAGGATTCGGAGCTGCCCCCGCAGACGGCCTCCGAGGCT CCCAGTGAGGGGTCTAGGAGAAGCTCATCCGACCTCATCACCCTCCCAGCCACCACTCCCCCATGTCCC ACCAAGAAGGAATGGGAAGGGCCAGCCACCTCGTACATGACATGCAGCGCCTACCAGAAGGTCCAGGAC TCGGAGATCAGCTTCCCCGCGGGCGTGGAGGTGCAGGTGCTGGAGAAGCAGGAGAGCGGGTGGTGGTAT GTGAGGTTTGGGGAGCTGGAGGGCTGGGCCCCTTCCCACTATTTGGTGCTGGATGAGAACGAGCAACCT GACCCCTCTGGCAAAGAGCTGGACACAGTGCCCGCCAAGGGCAGGCAGAACGAAGGCAAATCAGACAGC CTGGAGAAGATCGAGAGGCGCGTCCAAGCACTGAACACCGTCAACCAGAGCAAGAAGGCCACGCCCCCC ATCCCCTCCAAACCTCCCGGGGGCTTCGGCAAGACCTCAGGCACTCCAGCGGTGAAGATGAGGAACGGA GTGCGGCAGGTGGCGGTCAGGCCCCAGTCGGTGTTTGTGTCCCCGCCACCCAAGGACAACAACCTGTCC TGCGCCCTGCGGAGGAATGAGTCACTCACGGCCACTGATGGCCTCCGAGGCGTCCGACGGAACTCCTCC TTTAGCACTGCTCGCTCCGCTGCCGCCGAGGCCAAGGGCCGCCTGGCCGAACGGGCTGCCAGCCAGGGT TCAGACTCACCCCTACTGCCCGCCCAGCGCAACAGCATACCCGTGTCCCCTGTGCGCCCCAAGCCCATC GAGAAGTCTCAGTTCATCCACAATAACCTCAAAGATGTGTACGTCTCTATCGCAGACTACGAGGGGGAT GAGGAGACAGCAGGCTTCCAGGAGGGGGTGTCCATGGAGGTTCTGGAGAGGAACCCTAATGGCTGGTGG TACTGCCAGATCCTGGATGGTGTGAAGCCCTTCAAAGGCTGGGTGCCTTCCAACTACCTTGAGAAAAAG AACTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_014631 |
| Insert Size | 3318 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014631.2 |
| RefSeq Size | 11264 bp |
| RefSeq ORF | 3318 bp |
| Locus ID | 9644 |
| UniProt ID | Q5TCZ1 |
| MW | 121.8 kDa |
| Gene Summary | Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217487 | SH3PXD2A (Myc-DDK-tagged)-Human SH3 and PX domains 2A (SH3PXD2A) |
CNY 11544.00 |
|
| RC217487L1 | Lenti ORF clone of Human SH3 and PX domains 2A (SH3PXD2A), Myc-DDK-tagged |
CNY 13944.00 |
|
| RC217487L2 | Lenti ORF clone of Human SH3 and PX domains 2A (SH3PXD2A), mGFP tagged |
CNY 13944.00 |
|
| RC217487L3 | Lenti ORF clone of Human SH3 and PX domains 2A (SH3PXD2A), Myc-DDK-tagged |
CNY 12920.00 |
|
| RC217487L4 | Lenti ORF clone of Human SH3 and PX domains 2A (SH3PXD2A), mGFP tagged |
CNY 12920.00 |
|
| RG217487 | SH3PXD2A (tGFP-tagged) - Human SH3 and PX domains 2A (SH3PXD2A) |
CNY 12160.00 |
