PLEKHN1 (NM_032129) Human Untagged Clone
CAT＃: SC305403
PLEKHN1 (untagged)-Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 1
CNY 9880.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLPABP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC305403 representing NM_032129.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGGAACAGCCACTGTGTCCCTCAGGCCCCCAGGAGGCTCCGGGCCTCCTTCTCCAGAAAGCCCTCG CTGAAGGGAAACAGAGAGGACAGCGCGCGGATGTCGGCCGGCCTGCCGGGCCCCGAGGCTGCTCGAAGC GGGGACGCCGCCGCCAACAAGCTCTTCCACTACATCCCGGGCACGGACATCCTGGACCTGGAGAACCAG CGAGAAAACCTGGAGCAGCCATTCCTGAGTGTGTTCAAGAAGGGGCGGCGGAGGGTGCCTGTGAGGAAC CTGGGAAAAGTTGTGCATTACGCCAAGGTCCAGCTGCGGTTCCAGCACAGCCAGGATGTCAGCGACTGC TACCTGGAGCTATTCCCCGCCCACCTGTACTTCCAGGCCCACGGCTCGGAAGGACTCACATTTCAGGGG CTGTTACCGCTGACGGAGCTGAGTGTCTGCCCGCTCGAGGGGTCCCGAGAGCACGCCTTCCAGATCACA GGCCCACTGCCCGCACCCCTCCTGGTGCTCTGCCCCAGCCGGGCCGAGCTGGACCGCTGGCTTTACCAC CTGGAGAAGCAGACGGCCCTCCTCGGGGGGCCGCGGCGCTGCCACTCGGCACCCCCACAGCGCCGTCTA ACCCGGCTGCGGACGGCGTCAGGGCACGAACCCGGCGGCAGTGCTGTCTGTGCCTCGAGGGTCAAGCTG CAGCACCTGCCCGCACAGGAGCAGTGGGACCGGCTCTTGGTCCTGTACCCAACGTCCTTGGCCATTTTC TCCGAGGAGCTGGACGGGCTTTGCTTCAAGGGGGAGCTCCCACTCCGTGCCGTCCACATCAACCTGGAG GAGAAGGAGAAGCAGATCCGCTCCTTCCTGATTGAAGGCCCCCTCATCAACACCATCCGCGTGGTGTGC GCCAGCTACGAGGACTACGGTCACTGGCTGCTGTGCCTTCGCGCTGTCACCCACAGGGAGGGGGCCCCG CCGCTGCCTGGTGCCGAGAGCTTCCCAGGGTCGCAGGTTATGGGCAGTGGCCGAGGCTCACTCTCCTCA GGCGGACAGACCAGCTGGGACTCGGGGTGCTTGGCGCCCCCCTCCACCCGCACCAGCCACTCCCTGCCT GAGTCCTCAGTGCCATCCACCGTGGGCTGCTCCTCCCAGCACACACCGGACCAGGCCAACTCTGACCGT GCCAGCATTGGCCGACGGAGGACCGAGCTGAGACGCAGTGGCAGCAGCCGGTCACCCGGGAGCAAGGCC CGGGCAGAGGGCCGCGGCCCTGTCACCCCACTGCACCTGGACCTGACCCAGCTGCACAGGCTGAGCCTG GAGAGCAGCCCAGATGCCCCTGACCACACTTCGGAAACATCACACTCGCCCCTCTATGCCGACCCCTAC ACACCACCCGCCACCTCCCACCGCAGGGTCACAGATGTCCGGGGCCTGGAGGAGTTCCTCAGTGCCATG CAGAGTGCACGTGGACCCACGCCCTCGAGCCCACTCCCCTCGGTGCCTGTGTCTGTGCCTGCCTCTGAC CCTCGCTCCTGCTCCTCCGGCCCCGCTGGCCCCTACTTGCTCTCCAAGAAGGGAGCCCTGCAGTCCAGA GCCGCTCAGAGACACCGGGGCTCAGCCAAGGATGGGGGGCCGCAGCCCCCAGACGCCCCTCAGCTTGTC TCCTCTGCCAGGGAAGGTTCGCCCGAACCCTGGCTGCCTCTGACAGATGGTCGGTCCCCCAGGAGGAGC CGGGACCCCGGCTACGACCACCTCTGGGACGAGACTTTGTCTTCCTCCCACCAGAAGTGCCCCCAGCTT GGAGGGCCTGAGGCCAGTGGGGGGCTTGTGCAGTGGATCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_032129 |
| Insert Size | 1836 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032129.2 |
| RefSeq Size | 2404 bp |
| RefSeq ORF | 1836 bp |
| Locus ID | 84069 |
| UniProt ID | Q494U1 |
| MW | 66.4 kDa |
| Gene Summary | Controls the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR, in cooperation with the RNA stabilizer ELAVL1 (PubMed:29180010). Decreases the stability of the leptin mRNA by antagonizing the function of ELAVL1 by inducing its atypical recruitment from the nucleus to the cytosol (By similarity). Binds to cardiolipin (CL), phosphatidic acid (PA), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylserine (PS) (PubMed:18191643). Promotes apoptosis by enhancing BAX-BAK hetro-oligomerization via interaction with BID in colon cancer cells (PubMed:29531808) (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223977 | PLEKHN1 (Myc-DDK-tagged)-Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 1 |
CNY 4552.00 |
|
| RC223977L3 | Lenti ORF clone of Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 1, Myc-DDK-tagged |
CNY 7320.00 |
|
| RC223977L4 | Lenti ORF clone of Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 1, mGFP tagged |
CNY 7320.00 |
|
| RG223977 | PLEKHN1 (tGFP-tagged) - Human pleckstrin homology domain containing, family N member 1 (PLEKHN1), transcript variant 1 |
CNY 5990.00 |
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