VNN2 (NM_078488) Human Untagged Clone
CAT＃: SC305777
VNN2 (untagged)-Human vanin 2 (VNN2), transcript variant 2
CNY 7220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FOAP-4; GPI-80 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC305777 representing NM_078488.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAACGAGAATATAGACATTCTGGAGACAGCGATCAAGCAGGCAGCTGAGCAGGGTGCTCGAATCATT GTGACTCCAGAAGATGCACTTTATGGATGGAAATTTACCAGGGAAACTGTTTTCCCTTATCTGGAGGAT ATCCCAGACCCTCAGGTGAACTGGATTCCGTGTCAAGACCCCCACAGATTTGGTCACACACCAGTACAA GCAAGACTCAGCTGCCTGGCCAAGGACAACTCTATCTATGTCTTGGCAAATTTGGGGGACAAAAAGCCA TGTAATTCCCGTGACTCCACATGTCCTCCTAATGGCTACTTTCAATACAATACCAATGTGGTGTATAAT ACAGAAGGAAAACTCGTGGCACGTTACCATAAGTACCACCTGTACTCTGAGCCTCAGTTTAATGTCCCT GAAAAGCCGGAGTTGGTGACTTTCAACACCGCATTTGGAAGGTTTGGCATTTTCACGTGCTTTGATATA TTCTTCTATGATCCTGGTGTTACCCTGGTGAAAGATTTCCATGTGGACACCATACTGTTTCCCACAGCT TGGATGAACGTTTTGCCCCTTTTGACAGCTATTGAATTCCATTCAGCTTGGGCAATGGGAATGGGAGTT AATCTTCTTGTGGCCAACACACATCATGTCAGCCTAAATATGACAGGAAGTGGTATTTATGCACCAAAT GGTCCCAAAGTGTATCATTATGACATGAAGACAGAGTTGGGAAAACTTCTCCTTTCAGAGGTGGATTCA CATCCCCTATCCTCGCTTGCCTACCCAACAGCTGTTAATTGGAATGCCTACGCCACCACCATCAAACCA TTTCCAGTACAGAAAAACACTTTCAGGGGATTTATTTCCAGGGATGGGTTCAACTTCACAGAACTTTTT GAAAATGCAGGAAACCTTACAGTCTGTCAAAAGGAGCTTTGCTGTCATTTAAGCTACAGAATGTTACAA AAAGAAGAGAATGAAGTATACGTTCTAGGAGCTTTTACAGGATTACATGGCCGAAGGAGAAGAGAGTAC TGGCAGGTCTGCACAATGCTGAAGTGCAAAACTACTAATTTGACAACTTGTGGACGGCCAGTAGAAACT GCTTCTACAAGATTTGAAATGTTCTCCCTCAGTGGCACATTTGGAACAGAGTATGTTTTTCCTGAAGTG CTACTTACCGAAATTCATCTGTCACCTGGAAAATTTGAGGTGCTGAAAGATGGGCGTTTGGTAAACAAG AATGGATCATCTGGGCCTATACTAACAGTGTCACTCTTTGGGAGGTGGTACACAAAGGACTCACTTTAC AGCTCATGTGGGACCAGCAATTCAGCAATAACTTACCTGCTAATATTCATATTATTAATGATCATAGCT TTGCAAAATATTGTAATGTTATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_078488 |
| Insert Size | 1404 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_078488.2 |
| RefSeq Size | 1961 bp |
| RefSeq ORF | 1404 bp |
| Locus ID | 8875 |
| UniProt ID | O95498 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 52.9 kDa |
| Gene Summary | This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream codon, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213006 | VNN2 (Myc-DDK-tagged)-Human vanin 2 (VNN2), transcript variant 2 |
CNY 3656.00 |
|
| RC213006L3 | Lenti-ORF clone of VNN2 (Myc-DDK-tagged)-Human vanin 2 (VNN2), transcript variant 2 |
CNY 5890.00 |
|
| RC213006L4 | Lenti-ORF clone of VNN2 (mGFP-tagged)-Human vanin 2 (VNN2), transcript variant 2 |
CNY 5890.00 |
|
| RG213006 | VNN2 (tGFP-tagged) - Human vanin 2 (VNN2), transcript variant 2 |
CNY 5256.00 |
