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SP7 (NM_152860) Human Untagged Clone
CAT＃: SC306509
SP7 (untagged)-Human Sp7 transcription factor (SP7), transcript variant 2
CNY 5,488.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OI11; OI12; osterix; OSX |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_152860 edited
CTCCTTGGGACCCGTTCCCCAGCCTCAGGATGGCGTCCTCCCTGCTTGAGGAGGAAGTTC ACTATGGCTCCAGTCCCCTGGCCATGCTGACGGCAGCGTGCAGCAAATTTGGTGGCTCTA GCCCTCTGCGGGACTCAACAACTCTGGGCAAAGCAGGCACAAAGAAGCCGTACTCTGTGG GCAGTGACCTTTCAGCCTCCAAAACCATGGGGGATGCTTATCCAGCCCCCTTTACAAGCA CTAATGGGCTCCTTTCACCTGCAGGCAGTCCTCCAGCACCCACCTCAGGCTATGCTAATG ATTACCCTCCCTTTTCCCACTCATTCCCTGGGCCCACAGGCACCCAGGACCCTGGGCTAC TAGTGCCCAAGGGGCACAGCTCTTCTGACTGTCTGCCCAGTGTCTACACCTCTCTGGACA TGACACACCCCTATGGCTCCTGGTACAAGGCAGGCATCCATGCAGGCATTTCACCAGGCC CAGGCAACACTCCTACTCCATGGTGGGATATGCACCCTGGAGGCAACTGGCTAGGTGGTG GGCAGGGCCAGGGTGATGGGCTGCAAGGGACACTGCCCACAGGTCCAGCTCAGCCTCCAC TGAACCCCCAGCTGCCCACCTACCCATCTGACTTTGCTCCCCTTAATCCAGCCCCCTACC CAGCTCCCCACCTCTTGCAACCAGGGCCCCAGCATGTCTTGCCCCAAGATGTCTATAAAC CCAAGGCAGTGGGAAATAGTGGGCAGCTAGAAGGGAGTGGTGGAGCCAAACCCCCACGGG GTGCAAGCACTGGGGGTAGTGGTGGATATGGGGGCAGTGGGGCAGGGCGCTCCTCCTGCG ACTGCCCTAATTGCCAGGAGCTAGAGCGGCTGGGAGCAGCAGCGGCTGGGCTGCGGAAGA AGCCCATCCACAGCTGCCACATCCCTGGCTGCGGCAAGGTGTATGGCAAGGCTTCGCACC TGAAGGCCCACTTGCGCTGGCACACAGGCGAGAGGCCCTTCGTCTGCAACTGGCTCTTCT GCGGCAAGAGGTTCACTCGTTCGGATGAGCTGGAGCGTCATGTGCGCACTCACACCCGGG AGAAGAAGTTCACCTGCCTGCTCTGCTCCAAGCGCTTTACCCGAAGTGACCACCTGAGCA AACACCAGCGCACCCACGGAGAACCAGGCCCGGGTCCCCCTCCCAGTGGCCCCAAGGAGC TGGGGGAGGGCCGCAGCACGGGGGAAGAGGAGGCCAGTCAGACGCCCCGACCTTCTGCCT CGCCAGCAACCCCAGAGAAAGCCCCTGGAGGCAGCCCTGAGCAGAGCAACTTGCTGGAGA TCTGAGCCGGGTGGAAGGTCTCCCACCCCAGGG >OriGene 5' read for NM_152860 unedited
GTCAACATTTGTATACGACTCATATAGGGCGGCCGCGAATCGCCCTTCTGGCTCCTTGGG ACCCGTTCCCCACCTCAGGAGGCGTCCTCCCTGCTTGAGGAGGAAGTTCACTATGGCTCC AGTCCCCTGGCCATGCTGACGGCAGCGTGCAGCAAATTTGGTGGCTCTAGCCCTCTGCGG GACTCAACAACTCTGGGCAAAGCAGGCACAAAGAAGCCGTACTCTGTGGGCAGTGACCTT TCAGCCTCCAAAACCATGGGGGATGCTTATCCAGCCCCCTTTACAAGCACTAATGGGCTC CTTTCACCTGCAGGCAGTCCTCCAGCACCCACCTCAGGCTATGCTAATGATTACCCTCCC TTTTCCCACTCATTCCCTGGGCCCACAGGCACCCAGGACCCTGGGCTACTAGTGCCCAAG GGGCACAGCTCTTCTGACTGTCTGCCCAGTGTCTACACCTCTCTGGACATGACACACCCC TATGGCTCCTGGTACAAGGCAGGCATCCATGCAGGCATTTCACCAGGCCCAGGCAACACT CCTACTCCATGGTGGGATATGCACCCTGNAGGCAACTGGCTAGGTGGTGGGCAGGGCCAG GGTGATGGGCTGCAANGGACACTGCCCACAGGTCCAGCTCAGCCTCCACTGAACCCCCAG CTGCCCACCTACCCATCTGACTTTGCTCCCCTTAATCCAGCCCCCTACCCAGCTCCCCAC CTCTTGNCACCAGGGCCCCAGCATGTCCGGCCCCAAGATGTCTATTAACCCAAAGCAGTG GGAAATAGTGGGCAGCTAGAAAGGAGATGGTGGACCCAACCCCCACGGNGTTGCAAAGCA CTGGGGTAGTGGTTGAATATGGGGCAGTGGGGCN |
| Restriction Sites | Please inquire |
| ACCN | NM_152860 |
| Insert Size | 1400 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152860.1, NP_690599.1 |
| RefSeq Size | 2995 bp |
| RefSeq ORF | 1296 bp |
| Locus ID | 121340 |
| UniProt ID | Q8TDD2 |
| Protein Families | ES Cell Differentiation/IPS, Transcription Factors |
| Gene Summary | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A recessive form of craniodiaphyseal dysplasia caused by a homozygous missense variant in SP7/Osterix.
,null,
Bone
,PubMed ID 36436818
[SP7]
|
|
Osterix and RUNX2 are Transcriptional Regulators of Sclerostin in Human Bone
,Pérez-Campo, FM;Santurtún, A;García-Ibarbia, C;Pascual, MA;Valero, C;Garcés, C;Sañudo, C;Zarrabeitia, MT;Riancho, JA;,
Calcif. Tissue Int.
,PubMed ID 27154028
[SP7]
|
|
Regulation of the Bone-restricted IFITM-like ( Bril ) Gene Transcription by Sp and Gli Family Members and CpG Methylation
,null,
The Journal of Biological Chemistry
,PubMed ID 23530031
[SP7]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210939 | SP7 (Myc-DDK-tagged)-Human Sp7 transcription factor (SP7), transcript variant 2 |
CNY 5,488.00 |
|
| RC210939L1 | Lenti ORF clone of Human Sp7 transcription factor (SP7), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210939L2 | Lenti ORF clone of Human Sp7 transcription factor (SP7), transcript variant 2, mGFP tagged |
CNY 7,888.00 |
|
| RC210939L3 | Lenti ORF clone of Human Sp7 transcription factor (SP7), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210939L4 | Lenti ORF clone of Human Sp7 transcription factor (SP7), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG210939 | SP7 (tGFP-tagged) - Human Sp7 transcription factor (SP7), transcript variant 2 |
CNY 7,088.00 |
