Girdin (CCDC88A) (NM_018084) Human Untagged Clone
CAT＃: SC308873
CCDC88A (untagged)-Human coiled-coil domain containing 88A (CCDC88A), transcript variant 2
CNY 13632.00
货期*
现货
规格
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO; PEHOL |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_018084, the custom clone sequence may differ by one or more nucleotides
ATGGAGAACGAAATTTTTACTCCCCTTCTGGAGCAGTTCATGACCAGCCCTTTGGTCACT TGGGTTAAAACGTTTGGACCTCTGGCCGCAGGAAATGGGACCAACCTTGATGAATATGTG GCTTTGGTGGATGGGGTATTCTTGAACCAGGTCATGCTCCAAATTAATCCTAAATTGGAG AGTCAGAGAGTAAATAAAAAAGTCAATAATGATGCCTCACTTAGAATGCACAATCTATCC ATTTTGGTGAGACAGATAAAATTTTATTACCAGGAGACTTTGCAGCAATTGATCATGATG TCGTTGCCAAATGTCTTAATCATTGGCAAAAATCCCTTTTCTGAACAAGGCACAGAAGAA GTTAAAAAACTGCTTTTACTTTTATTGGGTTGTGCAGTTCAGTGTCAGAAAAAAGAGGAA TTTATTGAAAGAATTCAAGGTTTAGATTTTGATACAAAAGCAGCGGTTGCCGCACATATT CAAGAGGTAACTCATAATCAGGAAAATGTGTTTGACCTGCAATGGATGGAAGTGACTGAT ATGTCGCAGGAGGACATAGAACCACTCTTGAAAAATATGGCATTGCATCTAAAAAGACTT ATAGATGAGAGAGATGAACATTCAGAGACTATCATAGAACTCTCTGAAGAGCGGGATGGT CTCCATTTTCTACCCCATGCCTCTTCATCTGCACAGTCACCCTGTGGTTCTCCAGGCATG AAGCGAACAGAAAGTCGACAACATCTGTCGGTGGAACTGGCAGATGCTAAAGCCAAGATA AGAAGGCTTAGGCAGGAATTGGAGGAAAAGACTGAGCAGTTGTTGGATTGTAAACAAGAA CTTGAGCAAATGGAAATAGAACTCAAAAGGCTGCAACAAGAGAACATGAATTTGCTTTCG GATGCTCGCTCTGCCAGAATGTACCGAGATGAATTAGATGCACTTCGAGAGAAAGCAGTC AGAGTCGATAAGCTTGAAAGTGAAGTCAGCAGATATAAAGAGAGACTACATGATATTGAA TTTTATAAGGCAAGAGTTGAGGAATTAAAAGAAGACAATCAAGTTTTATTAGAAACAAAA ACCATGTTGGAAGACCAACTAGAGGGAACTCGTGCTCGTTCTGATAAATTACATGAATTA GAAAAAGAGAACTTACAACTGAAAGCTAAACTTCATGATATGGAAATGGAACGAGATATG GATAGAAAAAAGATTGAAGAATTAATGGAAGAAAATATGACTTTGGAAATGGCACAGAAA CAAAGTATGGATGAATCATTACATCTTGGCTGGGAACTGGAACAGATATCCAGAACTAGT GAACTTTCCGAAGCACCCCAGAAATCCCTGGGCCATGAGGTGAATGAGTTGACATCAAGT AGATTATTGAAGCTAGAGATGGAAAATCAAAGTTTGACAAAAACCGTAGAAGAGCTTCGG ACTACTGTGGATTCTGTAGAAGGCAATGCTTCCAAAATCCTGAAAATGGAAAAAGAAAAT CAAAGGCTCAGTAAAAAGGTTGAGATTCTTGAAAATGAGATTGTTCAAGAAAAGCAAAGT CTTCAGAATTGTCAGAATTTAAGCAAGGATCTAATGAAGGAGAAAGCTCAGCTTGAAAAA ACAATAGAAACACTGAGAGAAAATTCAGAGAGACAGATTAAGATACTGGAACAGGAAAAT GAACATCTGAATCAAACAGTGTCTTCCTTAAGGCAGCGGTCCCAGATAAGTGCAGAAGCA AGAGTGAAAGACATTGAAAAAGAAAACAAAATTCTTCATGAATCTATCAAAGAAACAAGT AGCAAGCTAAGCAAGATTGAATTTGAAAAAAGACAAATTAAAAAAGAATTGGAACATTAT AAAGAAAAAGGAGAACGAGCTGAAGAACTTGAAAATGAATTGCATCATCTTGAAAAAGAA AATGAATTATTACAGAAAAAAATAACTAATTTAAAAATTACTTGTGAAAAAATTGAGGCC TTAGAACAAGAAAATTCAGAGCTAGAAAGAGAAAATAGAAAATTAAAAAAAACATTGGAT AGCTTTAAAAATCTGACCTTTCAGTTAGAATCCCTAGAAAAAGAGAATTCCCAACTTGAT GAGGAAAACTTAGAACTGCGAAGGAATGTAGAATCTTTGAAGTGTGCAAGCATGAAAATG GCTCAGCTACAGCTAGAAAACAAAGAACTGGAAAGTGAAAAAGAGCAACTTAAGAAGGGT TTGGAGCTCCTGAAAGCATCTTTCAAGAAAACAGAACGCTTAGAAGTTAGCTACCAGGGT TTAGATATAGAAAATCAAAGACTGCAAAAAACTTTAGAGAACAGCAATAAAAAAATCCAG CAATTAGAGAGTGAACTACAAGACTTAGAGATGGAAAATCAAACATTGCAGAAAAACCTA GAAGAACTAAAAATATCTAGCAAAAGACTAGAACAGCTGGAAAAAGAAAATAAATCATTA GAGCAAGAGACTTCTCAACTGGAAAAGGATAAGAAACAATTGGAGAAGGAAAATAAGAGA CTCCGACAACAAGCAGAAATTAAAGATACCACATTAGAAGAAAATAATGTGAAGATTGGA AATTTGGAAAAAGAAAACAAAACCCTATCCAAAGAAATTGGTATATATAAAGAATCTTGT GTCCGTCTGAAAGAACTAGAAAAAGAAAATAAGGAGCTTGTGAAAAGAGCAACTATTGAT ATAAAAACGTTGGTTACACTACGTGAGGATTTGGTGAGTGAAAAGTTGAAGACCCAACAG ATGAACAATGATCTCGAAAAATTAACTCATGAGCTTGAGAAGATAGGGTTAAATAAGGAG CGACTCTTACATGATGAACAAAGTACTGATGACAGTAGGTATAAACTTTTGGAATCAAAA TTAGAATCCACTCTTAAGAAGTCTCTTGAAATAAAAGAAGAAAAAATTGCTGCTTTAGAA GCTCGATTAGAAGAATCCACGAATTATAACCAGCAATTGCGCCAAGAACTTAAAACAGTG AAAAAAAATTATGAAGCTCTCAAACAGAGACAAGATGAGGAAAGGATGGTACAGAGCTCT CCTCCAATATCTGGTGAAGACAACAAATGGGAGCGAGAAAGTCAAGAAACGACTAGAGAA CTTCTGAAAGTTAAAGACAGATTAATTGAAGTAGAAAGAAATAATGCTACACTGCAAGCA GAGAAGCAAGCGTTGAAAACTCAACTGAAGCAACTTGAGACACAGAACAATAATTTGCAG GCTCAGATTCTTGCACTTCAGAGGCAGACAGTGTCATTACAAGAACAGAATACCACTCTT CAAACACAGAATGCCAAGCTTCAGGTTGAAAATTCCACCCTTAATTCCCAAAGTACCTCA CTCATGAACCAGAATGCCCAACTCCTAATCCAGCAGTCTTCCTTAGAAAATGAAAATGAA TCTGTAATCAAAGAGCGAGAAGACCTAAAATCTCTCTATGATTCTCTGATCAAAGATCAT GAAAAGCTGGAACTTCTTCATGAACGTCAGGCTTCAGAGTATGAATCTCTTATCTCTAAA CATGGAACTCTGAAGTCTGCCCACAAAAATCTTGAGGTGGAACATAGAGACCTTGAAGAC CGTTACAATCAGTTATTAAAACAGAAAGGACAGTTGGAAGATTTGGAAAAAATGCTCAAA GTAGAACAGGAAAAAATGCTGCTTGAAAATAAAAATCATGAAACAGTAGCTGCAGAATAC AAGAAACTTTGTGGTGAAAATGATAGGCTGAATCATACCTATAGTCAACTTTTAAAAGAG ACTGAAGTTTTACAAACTGACCATAAAAATTTGAAAAGTCTTCTGAATAATTCCAAACTG GAACAAACAAGATTAGAAGCTGAATTTTCAAAACTAAAGGAACAATACCAACAATTGGAT ATTACATCAACCAAGCTGAATAACCAGTGTGAGTTGCTAAGCCAACTTAAAGGAAATTTA GAAGAAGAAAATCGGCATCTACTAGATCAAATTCAGACATTAATGCTACAGAACAGAACA CTTTTGGAGCAGAATATGGAAAGCAAGGATCTTTTTCATGTTGAACAAAGACAGTACATT GATAAGTTAAATGAATTAAGACGTCAGAAGGAGAAACTAGAAGAGAAAATTATGGATCAA TACAAATTTTATGACCCATCTCCTCCTAGAAGGAGAGGCAACTGGATTACTCTAAAAATG AGAAAATTGATAAAGTCTAAGAAAGATATTAATCGGGAACGCCAGAAATCTCTAACATTA ACACCCACCCGCTCAGACTCCAGTGAAGGATTTCTTCAGCTCCCTCATCAAGACAGTCAA GATAGTTCTTCAGTAGGTTCAAACTCTTTAGAAGATGGCCAGACCTTGGGGACCAAGAAA AGCAGCACCATGAATGACCTGGTGCAGTCCATGGTCCTAGCAGGACAGTGGACAGGTAGT ACTGAGAATTTGGAGGTTCCTGATGATATTTCAACGGGTAAAAGGAGAAAAGAATTGGGA GCTATGGCCTTCTCTACTACAGCCATCAACTTTTCAACTGTCAACTCTTCTGCAGGCTTC AGATCCAAGCAGTTGGTTAATAATAAAGATACTACATCCTTTGAAGACATAAGTCCACAA GGTGTTAGTGATGATTCTAGTACGGGATCAAGAGTTCATGCTTCAAGACCAGCCAGCCTT GATAGTGGCAGAACATCCACTAGCAATAGCAATAATAATGCTTCACTACATGAAGTCAAA GCAGGTGCAGTTAATAACCAAAGCAGGCCACAAAGCCACAGCAGTGGAGAATTTAGCCTG CTTCATGACCATGAGGCTTGGTCCAGCAGTGGTAGCAGTCCAATCCAGTACTTGAAAAGA CAGACCAGATCAAGCCCAGTGCTCCAGCACAAAATATCTGAAACACTGGAGAGTCGACAT CACAAGATCAAAACTGGTTCCCCTGGAAGTGAAGTTGTTACTCTACAACAGTTTTTGGAA GAAAGCAATAAGCTTACCTCAGTACAGATAAAGTCCTCAAGTCAAGAGAATCTTTTAGAT GAAGTAATGAAAAGTTTGTCTGTCTCTTCTGACTTTTTGGGAAAAGACAAACCAGTTAGC TGTGGTCTGGCCAGGTCAGTAAGTGGAAAAACCCCAGGGGACTTCTATGATAGACGGACA ACTAAGCCTGAGTTTTTGAGACCTGGTCCTCGAAAAACTGAAGATACCTACTTCATTAGT TCTGCGGGAAAACCTACACCAGGCACTCAAGGAAAAATAAAATTAGTAAAAGAATCTTCT CTGTCACGACAATCAAAAGATAGTAACCCTTATGCAACTTTACCTCGTGCAAGCAGCGTG ATCTCAACTGCCGAAGGAACTACACGAAGGACAAGCATCCATGATTTTTTGACCAAGGAC AGTAGACTGCCTATATCAGTTGATTCACCACCAGCTGCTGCTGACAGCAACACCACTGCA GCATCTAATGTGGACAAAGTACAAGAAAGCAGAAATTCAAAAAGCAGGTCTAGGGAGCAA CAAAGCTCCTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_018084 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018084.3, NP_060554.3 |
| RefSeq Size | 9630 bp |
| RefSeq ORF | 5532 bp |
| Locus ID | 55704 |
| UniProt ID | Q3V6T2 |
| Gene Summary | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (2) uses an alternate splice site and lacks an exon in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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