SLCO1A2 (NM_134431) Human Untagged Clone
CAT＃: SC309088
SLCO1A2 (untagged)-Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1
CNY 4912.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OATP; OATP-A; OATP1A2; SLC21A3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC309088 representing NM_134431.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCGGCCGCGAATTCGGCACGAGGTGAAGAGCAACATGGGAGAAACTGAGAAAAGAATTGAAACCCATAG AATAAGATGTCTTTTCAAGTTGAAGATGTTTCTGTTGGCAATAACATGTGCATTTGTATCCAAAACACT GTCTGGATCTTATATGAATTCCATGCTCACACAAATAGAGAGACAATTCAACATCCCAACATCTCTAGT TGGATTCATTAATGGAAGCTTTGAGATTGGAAATCTTTTGTTGATTATATTTGTGAGTTATTTTGGAAC CAAACTGCATAGACCTATAATGATTGGCATTGGATGTGTGGTTATGGGCTTAGGCTGTTTCTTAAAATC ACTACCTCATTTCCTCATGAACCAATATGAATATGAATCTACAGTTTCAGTTTCAGGCAACTTGTCCTC AAACAGTTTCTTGTGTATGGAAAATGGAACCCAGATTTTAAGACCAACGCAGGATCCATCAGAGTGTAC AAAGGAAGTTAAATCATTAATGTGGGTGTACGTCCTAGTAGGCAATATTGTACGTGGAATGGGTGAAAC TCCCATCCTGCCTTTGGGTATTTCCTATATAGAAGATTTTGCCAAATTTGAAAATTCTCCTTTATATAT TGGGCTTGTAGAAACAGGAGCTATTATTGGTCCTTTGATCGGACTTTTGTTGGCATCATTCTGTGCAAA TGTTTATGTTGACACTGGATTTGTGAACACAGATGATCTGATCATAACTCCCACTGACACTCGTTGGGT CGGTGCATGGTGGTTTGGCTTTCTGATTTGTGCAGGAGTTAACGTGCTCACTGCCATTCCTTTTTTCTT TTTGCCCAACACACTTCCAAAGGAAGGACTAGAGACTAATGCTGACATCATTAAAAATGAAAATGAAGA CAAACAAAAAGAAGAGGTCAAGAAGGAAAAATATGGAATCACTAAAGATTTTCTACCTTTCATGAAAAG TCTTTCCTGCAATCCAATTTATATGCTTTTCATACTTGTAAGTGTGATACAGTTCAATGCATTCGTTAA CATGATCTCCTTCATGCCTAAATACCTAGAACAGCAATATGGAATATCATCTTCAGATGCAATCTTTCT AATGGGTATTTATAACTTACCTCCAATATGTATTGGATATATAATTGGTGGTTTAATTATGAAGAAGTT CAAGATTACTGTCAAACAAGCTGCCCACATAGGATGTTGGTTATCCTTACTTGAGTATCTTCTCTATTT TTTATCTTTTCTCATGACTTGTGAAAATTCTTCAGTTGTTGGAATAAATACCTCTTATGAAGGAATTCC ACAAGATTTATATGTGGAAAATGACATCTTTGCTGATTGCAATGTGGATTGCAACTGTCCATCTAAAAT ATGGGATCCTGTGTGTGGAAACAATGGCTTGTCATATCTGTCAGCTTGTCTTGCTGGTTGTGAGACATC CATTGGAACGGGAATAAACATGGTGTTCCAAAATTGCAGCTGTATTCAAACATCAGGAAATTCATCTGC AGTTCTTGGGCTGTGCGACAAAGGACCTGACTGTTCCTTGATGCTCCAGTACTTCCTAATCTTGTCAGC GATGAGCAGTTTCATTTATTCTTTGGCTGCCATACCTGGATATATGGTTCTCTTGAGGTGTATGAAATC TGAAGAGAAGTCCCTTGGTGTGGGATTACATACATTTTGCACAAGAGTATTTGCTGGCATTCCTGCACC TATATATTTTGGCGCTTTAATGGATTCCACATGTTTACACTGGGGAACTTTGAAATGTGGTGAGTCAGG GGCATGCAGGATATATGATTCCACCACCTTCAGATACATCTACCTCGGATTGCCGGCAGCACTAAGAGG ATCAAGCTTTGTTCCAGCCTTAATCATCTTAATTCTTTTGAGGAAGTGTCATCTACCTGGTGAAAATGC CTCTTCAGGAACAGAGCTTATAGAGACAAAAGTCAAAGGGAAGGAAAATGAGTGCAAAGATATATACCA AAAGTCCACGGTTTTGAAAGATGATGAATTGAAAACTAAATTGTAATTGTCCTATTATATTACTTTTTT CAGAATTAGAGAACATGCTGTACAACTTAATTGTTTTAAAAATCAGTAGAGATATAATAGATAACTTTT TCTTGTCTTTAAGAACCTAAAAAACCTCTTAACTCAAAATAATAAAATGTTCACTAATGATAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_134431 |
| Insert Size | 2261 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | A 5' end in-Frame SNP, which changes amino acid from S to F, was observed. This SNP comes from a partial cDNA clone which is obtained from cDNA library. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_134431.1 |
| RefSeq Size | 3389 bp |
| RefSeq ORF | 2261 bp |
| Locus ID | 6579 |
| UniProt ID | P46721 |
| Protein Families | Transmembrane |
| MW | 90 kDa |
| Gene Summary | This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. The translation of this protein may be modulated by multiple upstream ORFs that are present in the 5' UTR. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Evaluation of Organic Anion Transporter 1A2-knockin Mice as a Model of Human Blood-Brain Barrier
,Sano, Y;Mizuno, T;Mochizuki, T;Uchida, Y;Umetsu, M;Terasaki, T;Kusuhara, H;,
Drug Metab. Dispos.
,PubMed ID 30154106
[SLCO1A2]
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Distinct Interaction of Nilotinib and Imatinib with P-Glycoprotein in Intracellular Accumulation and Cytotoxicity in CML Cell Line K562 Cells
,Yamakawa, Y;Hamada, A;Uchida, T;Sato, D;Yuki, M;Hayashi, M;Kawaguchi, T;Saito, H;,
Biol. Pharm. Bull.
,PubMed ID 25087954
[SLCO1A2]
|
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Interaction of Macrolide Antibiotics with Intestinally Expressed Human and Rat Organic Anion Transporting Polypeptides
,Tian Lan, Anuradha Rao, Jamie Haywood, Charles B. Davis, Chao Han, Eric Garver, and Paul A. Dawson,
Drug Metab. Dispos., Sep 2009; 10.1124/dmd.109.028522
[SLCO1A2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215450 | SLCO1A2 (Myc-DDK-tagged)-Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1 |
CNY 4912.00 |
|
| RC215450L1 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1, Myc-DDK-tagged |
CNY 7312.00 |
|
| RC215450L2 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1, mGFP tagged |
CNY 7700.00 |
|
| RC215450L3 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1, Myc-DDK-tagged |
CNY 7312.00 |
|
| RC215450L4 | Lenti ORF clone of Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1, mGFP tagged |
CNY 7700.00 |
|
| RG215450 | SLCO1A2 (tGFP-tagged) - Human solute carrier organic anion transporter family, member 1A2 (SLCO1A2), transcript variant 1 |
CNY 6512.00 |
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