AKR1B15 (NM_001080538) Human Untagged Clone
CAT＃: SC315736
AKR1B15 (untagged)-Human aldo-keto reductase family 1, member B15 (AKR1B15)
CNY 5610.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AK1R1B7; AKR1B10L; AKR1R1B7 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315736 representing NM_001080538.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGTCTTACAAATGGAACCCCAAGTGAACTCAACTAACAACTTCCACCAAGGACCCCTGGACCAACCC GTTGGCCCTTTGACTGGCCTAAAGAGTTCCCTTCTGAAGGACACTACAAGTGCAGGGCCCCTTCTTCGC CCCTATCCAGCATCTCTTCTCGGCAAAGTGAAAGAAGCGGTGAAGGTGGCCATTGATGCAGAATATCGC CACATTGACTGTGCCTATTTCTATGAGAATCAACATGAGGTGGGAGAAGCCATCCAAGAGAAGATCCAA GAGAAGGCTGTGATGCGGGAGGACCTGTTCATCGTCAGCAAGGTGTGGCCCACTTTCTTTGAGAGACCC CTTGTGAGGAAAGCCTTTGAGAAGACCCTCAAGGACCTGAAGCTGAGCTATCTGGACGTCTATCTTATT CACTGGCCACAGGGATTCAAGACTGGGGATGACTTTTTCCCCAAAGATGATAAAGGTAATATGATCAGT GGAAAAGGAACGTTCTTGGATGCCTGGGAGGCCATGGAGGAGCTGGTGGACGAGGGGCTGGTGAAAGCC CTTGGGGTCTCAAATTTCAACCACTTCCAGATCGAGAGGCTCTTGAACAAACCTGGACTGAAATATAAA CCAGTGACTAACCAGGTTGAGTGTCACCCATACCTCACGCAGGAGAAACTGATCCAGTACTGCCACTCC AAGGGCATCACCGTTACGGCCTACAGCCCCCTGGGCTCTCCGGATAGACCTTGGGCCAAACCTGAGGAC CCTTCCCTGCTGGAGGATCCCAAGATTAAGGAGATTGCTGCAAAGCACAAAAAAACCACAGCCCAGGTT CTGATCCGTTTCCATATCCAGAGGAATGTGACAGTGATCCCCAAGTCTATGACACCAGCACACATTGTT GAGAACATTCAGGTCTTTGACTTTAAATTGAGTGATGAGGAGATGGCAACCATACTCAGCTTCAACAGA AACTGGAGGGCCTTTGACTTCAAGGAATTCTCTCATTTGGAGGACTTTCCCTTCGATGCAGAATATTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001080538 |
| Insert Size | 1035 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001080538.2 |
| RefSeq Size | 1625 bp |
| RefSeq ORF | 1035 bp |
| Locus ID | 441282 |
| UniProt ID | C9JRZ8 |
| MW | 39.5 kDa |
| Gene Summary | Isoform 1: Catalyzes the NADPH-dependent reduction of a variety of carbonyl substrates, like aromatic aldehydes, alkenals, ketones and alpha-dicarbonyl compounds (PubMed:26222439, PubMed:21276782). In addition, catalyzes the reduction of androgens and estrogens with high positional selectivity (shows 17-beta-hydroxysteroid dehydrogenase activity) as well as 3-keto-acyl-CoAs (PubMed:25577493). Displays strong enzymatic activity toward all-trans-retinal and 9-cis-retinal (PubMed:26222439). May play a physiological role in retinoid metabolism (PubMed:26222439).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a). ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000457545.7/ ENSP00000389289.1 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219738 | AKR1B15 (Myc-DDK-tagged)-Human aldo-keto reductase family 1, member B15 (AKR1B15) |
CNY 3656.00 |
|
| RC219738L3 | Lenti ORF clone of Human aldo-keto reductase family 1, member B15 (AKR1B15), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC219738L4 | Lenti ORF clone of Human aldo-keto reductase family 1, member B15 (AKR1B15), mGFP tagged |
CNY 5890.00 |
|
| RG219738 | AKR1B15 (tGFP-tagged) - Human aldo-keto reductase family 1, member B15 (AKR1B15) |
CNY 4370.00 |
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