Septin 8 (SEPT8) (NM_001098812) Human Untagged Clone
CAT＃: SC316522
41525 (untagged)-Human septin 8 (SEPT8), transcript variant 3
CNY 7030.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SEP2; SEPT8 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001098812, the custom clone sequence may differ by one or more nucleotides
ATGGCGGCCACCGACCTGGAGCGCTTCTCGAATGCAGAGCCAGAGCCCCGGAGCCTCTCC CTGGGCGGCCATGTGGGTTTCGACAGCCTCCCCGACCAGCTGGTCAGCAAGTCGGTCACT CAGGGCTTCAGCTTCAACATCCTCTGTGTGGGGGAGACCGGCATTGGCAAATCCACACTG ATGAACACACTCTTCAACACGACCTTCGAGACTGAGGAAGCCAGTCACCATGAGGCATGC GTGCGCCTGCGGCCCCAGACCTATGACCTCCAGGAGAGCAACGTGCAGCTCAAGCTGACC ATTGTGGATGCCGTGGGCTTTGGGGATCAGATCAATAAGGATGAGAGTTACAGGCCCATA GTTGACTACATCGATGCGCAGTTTGAAAATTATCTGCAGGAGGAGCTGAAGATCCGCCGC TCGCTCTTCGACTACCATGACACAAGGATCCACGTTTGCCTCTACTTCATCACGCCCACA GGGCACTCCCTGAAGTCTCTAGATCTAGTGACCATGAAGAAACTAGACAGCAAGGTGAAC ATTATTCCCATCATCGCCAAGGCTGACACCATCTCCAAGAGCGAGCTCCACAAGTTCAAG ATCAAGATCATGGGCGAGTTGGTCAGCAACGGGGTCCAGATCTACCAGTTCCCCACGGAT GATGAGGCTGTTGCAGAGATTAACGCAGTCATGAATGCACATCTGCCCTTTGCCGTGGTG GGCAGCACCGAGGAGGTGAAGGTGGGGAACAAGCTGGTCCGAGCACGGCAGTACCCCTGG GGAGTGGTGCAGGTGGAGAATGAGAATCACTGCGACTTCGTGAAGCTGCGGGAGATGTTG ATCCGGGTGAACATGGAAGACCTCCGCGAGCAGACCCACAGCCGGCACTACGAGCTCTAC CGGCGCTGCAAGTTGGAGGAGATGGGCTTTCAGGACAGCGATGGTGACAGCCAGCCCTTC AGCCTACAAGAGACATACGAGGCCAAGAGGAAGGAGTTCCTAAGTGAGCTGCAGAGGAAG GAGGAAGAGATGAGGCAGATGTTTGTCAACAAAGTGAAGGAGACAGAGCTGGAGCTGAAG GAGAAGGAAAGGGAGCTCCATGAGAAGTTTGAGCACCTGAAGCGGGTCCACCAGGAGGAG AAGCGCAAGGTGGAGGAAAAGCGCCGGGAACTGGAGGAGGAGACCAACGCCTTCAATCGC CGGAAGGCTGCGGTGGAGGCCCTGCAGTCGCAGGCCTTGCACGCCACCTCGCAGCAGCCC CTGAGGAAGGACAAGGACAAGAAGAAAGCCAGTGGCTGGTCTTCCATTTACAGTGTCACT ATTCCC |
| Restriction Sites | Please inquire |
| ACCN | NM_001098812 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001098812.1, NP_001092282.1 |
| RefSeq Size | 4076 bp |
| RefSeq ORF | 1329 bp |
| Locus ID | 23176 |
| UniProt ID | Q92599 |
| Gene Summary | This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (3) differs in the 3' UTR and 3' coding region compared to variant 1. The resulting isoform (c) is shorter and has a distinct C-terminus compared to isoform a. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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SEPT8 modulates ß-amyloidogenic processing of APP via affecting the sorting and accumulation of BACE1
,Kurkinen, KM;Marttinen, M;Turner, L;Natunen, T;Mäkinen, P;Haapalinna, F;Sarajärvi, T;Gabbouj, S;Kurki, M;Paananen, J;Koivisto, AM;Rauramaa, T;Leinonen, V;Tanila, H;Soininen, H;Lucas, FR;Haapasalo, A;Hiltunen, M;,
J. Cell. Sci.
,PubMed ID 27084579
[SEPTIN8]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213606 | SEPT8 (Myc-DDK-tagged)-Human septin 8 (SEPT8), transcript variant 3 |
CNY 5488.00 |
|
| RC213606L1 | Lenti-ORF clone of 41525 (Myc-DDK-tagged)-Human septin 8 (SEPT8), transcript variant 3 |
CNY 7888.00 |
|
| RC213606L2 | Lenti-ORF clone of 41525 (mGFP-tagged)-Human septin 8 (SEPT8), transcript variant 3 |
CNY 5890.00 |
|
| RC213606L3 | Lenti-ORF clone of 41525 (Myc-DDK-tagged)-Human septin 8 (SEPT8), transcript variant 3 |
CNY 5890.00 |
|
| RC213606L4 | Lenti-ORF clone of 41525 (mGFP-tagged)-Human septin 8 (SEPT8), transcript variant 3 |
CNY 5890.00 |
|
| RG213606 | SEPT8 (tGFP-tagged)-Human septin 8 (SEPT8), transcript variant 3 |
CNY 4370.00 |
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