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LOX 1 (OLR1) (NM_002543) Human Untagged Clone
CAT＃: SC321097
OLR1 (untagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1
CNY 2,400.00
CNY 6,270.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLEC8A; LOX1; LOXIN; SCARE1; SLOX1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002543.3
AGTTTGTTGAAGTTCGTGACTGCTTCACTCTCTCATTCTTAGCTTGAATTTGGAAATGAC
TTTTGATGACCTAAAGATCCAGACTGTGAAGGACCAGCCTGATGAGAAGTCAAATGGAAA AAAAGCTAAAGGTCTTCAGTTTCTTTACTCTCCATGGTGGTGCCTGGCTGCTGCGACTCT AGGGGTCCTTTGCCTGGGATTAGTAGTGACCATTATGGTGCTGGGCATGCAATTATCCCA GGTGTCTGACCTCCTAACACAAGAGCAAGCAAACCTAACTCACCAGAAAAAGAAACTGGA GGGACAGATCTCAGCCCGGCAACAAGCAGAAGAAGCTTCACAGGAGTCAGAAAACGAACT CAAGGAAATGATAGAAACCCTTGCTCGGAAGCTGAATGAGAAATCCAAAGAGCAAATGGA ACTTCACCACCAGAATCTGAATCTCCAAGAAACACTGAAGAGAGTAGCAAATTGTTCAGC TCCTTGTCCGCAAGACTGGATCTGGCATGGAGAAAACTGTTACCTATTTTCCTCGGGCTC ATTTAACTGGGAAAAGAGCCAAGAGAAGTGCTTGTCTTTGGATGCCAAGTTGCTGAAAAT TAATAGCACAGCTGATCTGGACTTCATCCAGCAAGCAATTTCCTATTCCAGTTTTCCATT CTGGATGGGGCTGTCTCGGAGGAACCCCAGCTACCCATGGCTCTGGGAGGACGGTTCTCC TTTGATGCCCCACTTATTTAGAGTCCGAGGCGCTGTCTCCCAGACATACCCTTCAGGTAC CTGTGCATATATACAACGAGGAGCTGTTTATGCGGAAAACTGCATTTTAGCTGCCTTCAG TATATGTCAGAAGAAGGCAAACCTAAGAGCACAGTGAATTTGAAGGCTCTGGAAGAAAAG AAAAAAGTCTTTGAGTTTTATTCTGGAATTTAAGCTATTCTTTGTCACTTGGGTGCCAAA CATGAGAGCCCAGAAAACTGTCATTTAGCTGGCTGCAGAACTCCTTTGCAGAAACTGGGG TTCCAGGTGCCTGGCACCTTTATGTCAACATTTTTGATTCTAGCTATCTGTATTATTTCA CCTAGCTTGTCCCAAGCTTCCCTGCCAGCCTGAAGTCCATTTTCCCCTTTTTATTTTAAA ATTTGACTCCTCTTCAAGCTTGAAAACCCTCTGAACTCAGTCTTCTTTACCTCATTATCA CCTTCCCCTCACACTCCTAAAATTGCATGAAAGACAGAACATGGAGAACTTGCTCAAGTG CAGGCAGAGAGCAAAAAGGGGAAATATGTCTGGGAAAAAGTGCACGTGAAGAAACAAAGA AGGACAGAGGCCATTCCGAAATCAAGAAACTCATGTTCTTAACTTTAAAAAAGGTATCAA TCCTTGGTTTTTACACTGTGGTCCATCTCCAGACTCTACCACTTACAGACAGACAGACAG ACACACACACACACACACACACACACATTTTGGGACAAGTGGGGAGCCCAAGAAAGTAAT TAGTAAGTGAGTGGTCTTTTCTGTAAGCTAATCCACAACCTGTTACCACTTCCTGAATCA GTTATTATTTCTTCATTTTTTTTTCTACCAGAGGACAGATTAATAGATTTAACCCTTCAC GACAGTTCTTGTTAGAATCATGGGATGTGTGGCCCAGAGGTAAGAATAGAATTTCTTTCC CTAAAGAACATACCTTTTGTAGATGAACTCTTCTCAACTCTGTTTTGCTATGCTATAATT CCGAAACATACAAGACAAAAAAAATGAAGACACTCAATCTAGAACAAACTGAGCCAGGTA TGCAAATATCGCTGAATAGAAACAGATGGAATTAGAAATATATCTTCTATTTTTAGGCTT CTATTTCCTTTCCACCCACTCTTCACAGGCTATTCTACTTTAAAGGAAGCCTTTTTATTT TGCTGCACACAATCTAGCAGGAATCTTTTTTTTTTTTTTTAAGAGCTGTGTCATCCTTAT GTAGGCAAGAGATGTTTGCTTTTGTTAAAAGCTTTATTGAGATATAATTAACATAAAATA AACTGAACATATTTAAAGTGTACTATTTGATAAGTTTTCACACCTTGTGGAGAACATGCA TACTACAATTAAGAGAGTGAACATATCCATCATCCCTCAAAGTGTCACAATGCTCCTCCT GATGACTCCTCCCCAGAAAACCACCAATCGGCTTTCATTTTGCATTTTGTAGTTTTATGT GAATGGAATCATATAGTATGTCTTTTTTTTTTGTCTGGCTTCTTTCACTTTGCATAATTA TTTTGAGATTCATATGTCTCCATCTTGATGCTCGTATGAATTCATTCTTTTAAATGTTGA ATATTCCCTTGTATGGATATACCACAATTCATTTACCCATTTACTTGTTGATGACATTTG GGTTGTTTTAGTTTTGGGATATTACAAATAAAGCTGCTGTGAACATTTGTGCAAAAAAAA AAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002543 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002543.3, NP_002534.1 |
| RefSeq Size | 2533 bp |
| RefSeq ORF | 822 bp |
| Locus ID | 4973 |
| UniProt ID | P78380 |
| Domains | CLECT |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | PPAR signaling pathway |
| Gene Summary | This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Resveratrol attenuates oxidized LDL-evoked Lox-1 signaling and consequently protects against apoptotic insults to cerebrovascular endothelial cells
,Huai-Chia Chang, Tyng-Guey Chen, Yu-Ting Tai, Ta-Liang Chen, Wen-Ta Chiu, Ruei-Ming Chen,
Journal of Cerebral Blood Flow & Metabolism (13 October 2010) doi:10.1038/jcbfm.2010.180 Original Article
[OLR1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204704 | OLR1 (Myc-DDK-tagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1 |
CNY 2,400.00 |
|
| RC204704L1 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204704L2 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RC204704L3 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204704L4 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG204704 | OLR1 (tGFP-tagged) - Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1 |
CNY 4,000.00 |
|
| SC118589 | OLR1 (untagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1 |
CNY 2,400.00 |
