ELAVL1 (NM_001419) Human Untagged Clone
CAT＃: SC322158
ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1)
CNY 2400.00
CNY 2950.00
| Cited in 2 publications. |
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ELAV1; Hua; HUR; MelG |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322158
CCGTCGCCGCCACCGCCGCCACCGCTACCGAGGCCGAGCGGAGCCGTTAGCGCCGCGCCG
CCGCCGCCTCCCGCCCGCCCCGGAGCAGCCCCGGGCCCGCCCGCCCGCATCCAGATTTTT GAAAAATACAATGTCTAATGGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACAT CGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAGGATGAGTTACG AAGCCTGTTCAGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGC AGGACACAGCTTGGGCTATGGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGC GATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTGTCGTATGCTCG CCCGAGCTCAGAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCAT GACCCAGAAGGACGTAGAAGACATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGT CCTCGTGGATCAGACTACAGGTTTGTCCAGAGGGGTTGCGTTTATCCGGTTTGACAAACG GTCGGAGGCAGAAGAGGCAATTACCAGTTTCAATGGTCATAAACCCCCAGGTTCCTCTGA GCCCATCACAGTGAAGTTTGCAGCCAACCCCAACCAGAACAAAAACGTGGCACTCCTCTC GCAGCTGTACCACTCGCCAGCGCGACGGTTCGGAGGCCCCGTTCACCACCAGGCGCAGAG ATTCAGGTTCTCCCCCATGGGCGTCGATCACATGAGCGGGCTCTCTGGCGTCAACGTGCC AGGAAACGCCTCCTCCGGCTGGTGCATTTTCATCTACAACCTGGGGCAGGATGCCGACGA GGGGATCCTCTGGCAGATGTTTGGGCCGTTTGGTGCCGTCACCAATGTGAAAGTGATCCG CGACTTCAACACCAACAAGTGCAAAGGGTTTGGCTTTGTGACCATGACAAACTATGAAGA AGCCGCGATGGCCATAGCCAGCCTGAACGGCTACCGCCTGGGGGACAAAATCTTACAGGT TTCCTTCAAAACCAACAAGTCCCACAAATAACTCGCTCATGCTTTTTTTTGTACGGAATA GATAATTAAGAGTGAAGGAGTTGAAACTTTTCTTGTTAGTGTACAACTCATTTTGCGCCA ATTTTCACAAGTGTTTGTCTTTGTCTGAATGAGAAGTGAGAAGGTTTTTATACTCTGGGA TGCAACCGACATGTTCAAATGTTTGAAATCCCACAATGTTAGACCAATCTTAAGTTTCGT AAGTTATTTCCTTTAAGATATATATTAAACAGAAATCTAAGTAGAACTGCATTGACTAAC CAGTCCCTCTGGATGGTGGTGAACCTGAAGCATGCTTTAACCTCTAAGACTGTCTAACAC GCGTTTCATTCAATGTCTCCACAGACTGGGTAGCAAAAAAATCACCTTTTAGTTTTAGTT TTTAATCTAAAGATGTTAGACAGATGCTGAGTGTGCGTTTTCTCAACCGCTTCAACATTG TAAGCGATGTATGCTTTGGTTGACAGGAAGTTCCTTTTCCAGGCAGGTCCCGTTGCCACC TCCTGCTCACTCAGTCCCGGGCTCTGCCGAGTGGTCCTGGGAATGGCGGCGGGCCCGTCC AGCGTGGGCCACCACTGGGGCCGGGGGCCACGGGCTGCATGCTGGGCGGGCCCTCCAGAG AAGGACACAAACGTGTTTCGTAAGCCCAGGCACCAATGGGAATGGACCAAAGAGTTTCAG GGAAACTCCAGTATATTCCAGAGTCAGATCTAAGCTCCAGGCACGCCTGAAGATGTGTTG CTACTCTGACATCCCGAGTTTCTGTCCACACATTGCATGCACAGCGCCCCACACATTGGA TACTGTTGTTCACGATAATTTCTCCCGTTTTCCAGAGCATTTAACATAGCTTGGAGGCGT AAAATGGCTCTGTATTTTAATAACACAGAAACATTTGAGCATTGTATTTCTCGCATCCCT TCTCGTGAGCGCTTAGACCTTTTTCTATTTTAGTCGGATTTTGTTTTGGAATTTTGCTTT TGTATGAACACTCAGCAGAAAAGTACTTACTTCTTGCCAGTTATCTATTAACCAAAACCT TTGATTTGTAGTTTTAAAGATTAACCCTCAAAGTTCTCTTCATAACTGCCTTGACATTTT GGGTTGTTCTGTTCTGTTAATTTTCTTTTGCTTTTTTGTGTTTTTTGTTTGTTTTTACTT TTGCATTTAAGACCATTAAATTTGATTTTGTTTTGCTCGAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001419 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001419.2, NP_001410.2 |
| RefSeq Size | 6075 bp |
| RefSeq ORF | 981 bp |
| Locus ID | 1994 |
| UniProt ID | Q15717 |
| Domains | RRM |
| Gene Summary | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Interleukin-19 decreases leukocyte-endothelial cell interactions by reduction in endothelial cell adhesion molecule mRNA stability
,Ross N. England, Kyle J. Preston, Rosario Scalia, and Michael V. Autieri,
Am J Physiol Cell Physiol, Aug 2013; 305: C255 - C265.
,PubMed ID 23596173
[ELAVL1]
|
|
Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent
,Po-Chen Chu, Samuel K. Kulp, and Ching-Shih Chen,
Carcinogenesis, Aug 2013; 10.1093/carcin/bgt251.
,PubMed ID 23864387
[ELAVL1]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201562 | ELAVL1 (Myc-DDK-tagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) |
CNY 2400.00 |
|
| RC201562L1 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), Myc-DDK-tagged |
CNY 4800.00 |
|
| RC201562L2 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mGFP tagged |
CNY 5890.00 |
|
| RC201562L3 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC201562L4 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mGFP tagged |
CNY 4800.00 |
|
| RG201562 | ELAVL1 (tGFP-tagged) - Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) |
CNY 4000.00 |
|
| SC119271 | ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) |
CNY 2400.00 |
