RAB7B (NM_177403) Human Untagged Clone
CAT＃: SC323745
RAB7B (untagged)-Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1
CNY 2400.00
CNY 2950.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | RAB7 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_177403.3
GTGGCGTGGCTTCAACAGACTTTCTTTTGCCTGTCTTTGTCCCAGAGCCTCTTCCCTGGC
CCTGCTGAGACCACTGCTCTAAGAAGAGACCACCAGACTGAGAGAGGACTCCCAGCTGCC CTCAGAGCGGAGGCCGAGTGCTGCACAGCCACAGCTGCTCTGAAGCCCTTCCATGAATCC CCGGAAGAAGGTGGACCTGAAACTCATTATCGTCGGAGCCATTGGTGTGGGAAAGACCTC CCTCCTTCACCAATATGTGCACAAGACGTTTTATGAGGAATACCAGACCACACTGGGGGC CAGCATCCTCTCCAAGATTATCATATTGGGTGACACAACTTTGAAGTTACAGATCTGGGA CACGGGCGGTCAGGAGCGGTTCCGCTCCATGGTGTCCACGTTCTACAAGGGCTCCGATGG CTGCATCCTAGCTTTTGATGTCACCGACCTGGAGTCTTTTGAAGCCCTGGATATCTGGCG GGGTGATGTCCTGGCCAAGATTGTCCCCATGGAGCAGTCCTACCCCATGGTGTTGTTGGG GAACAAGATCGATCTGGCAGACCGGAAGGTACCCCAGGAAGTAGCTCAAGGCTGGTGTAG AGAGAAAGATATTCCTTACTTTGAAGTCAGTGCCAAGAATGACATCAATGTGGTGCAAGC GTTTGAGATGCTGGCCAGTAGGGCTCTGTCGAGGTACCAGAGCATCTTAGAAAATCACCT CACAGAATCCATCAAGCTCTCGCCAGACCAGTCAAGGAGCAGATGCTGCTGACCTCCAGA CGCCTGCTCTGGAAGCCCAGAAACAGAGCCTGCCCCGAGCCTGGTCACCCCAGGCTTGAG AACAGGTGACCATCCCCCTCCAGCCCCACTGCCTGCCCAAGCACAGTGCAGGGGGCCTAA GCTCTGCGGCAGAGCCCTTGACCCTGGTGCTGGGCCCAGAGTCAGAGGGCAGCCCCTGGC TCAGGCTGAGTATAGTGAGAGCGTCTGGATGAAGCCCGGAATGTCAGAGCCAAACCCTGG TCCTGCAGAAGTCACAGTTTCCGCAGTGGCTCCAGCTTTCCCCACCCATCCACCCCTCAA ACACTCCCGCTCCAGAACACACATCTCCGCAGACCGGCCACTGATTGGAGTCTGGTTACA TCCTCCTGTGGACAGACCTTCCTCACCCGCTCCCACCTCACACCCCTCAGCCACAAGCAA AGCTTTGGACAATGGCACAGCTCAGCCTCCTTCAACGAGCAGACTAAGGAGTAAAGGTCT GGACCCCACATGCTGGGCCCGCCTCAGCTCCTGGCAGAAGCTGTCGTGCCTGAGACCCCC TCTGCTCCCTCCAGGGTAGAAGACTGAGGGAGCACAGGAGAAGCCACAAGGGACCATGGC TCATTCCTCCTTGCTGGGTGCTCAGGCAACTCACATAAATCTCTGAGTCTCAATTTGTTT ATCTGTCCTGTGGGGGTGAGATGTGCCTTGCCCCCTGTATCACAGTGTGGTTTTGAGGAC CAGAAGCTGTGCTTAAATCCAGTAGCTGTTGTCAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_177403 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_177403.3, NP_796377.2 |
| RefSeq Size | 2330 bp |
| RefSeq ORF | 600 bp |
| Locus ID | 338382 |
| UniProt ID | Q96AH8 |
| Protein Families | Druggable Genome |
| Gene Summary | Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 2 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202283 | RAB7B (Myc-DDK-tagged)-Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1 |
CNY 2400.00 |
|
| RC202283L1 | Lenti ORF clone of Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1, Myc-DDK-tagged |
CNY 4800.00 |
|
| RC202283L2 | Lenti ORF clone of Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RC202283L3 | Lenti ORF clone of Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC202283L4 | Lenti ORF clone of Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RG202283 | RAB7B (tGFP-tagged) - Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1 |
CNY 4000.00 |
|
| SC106979 | RAB7B (untagged)-Human RAB7B, member RAS oncogene family (RAB7B), transcript variant 1 |
CNY 2400.00 |
