TNPO2 (NM_001136196) Human Untagged Clone
CAT＃: SC326278
TNPO2 (untagged)-Human transportin 2 (TNPO2), transcript variant 1
CNY 17290.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IPO3; KPNB2B; TRN2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC326278 representing NM_001136196.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGACTGGCAGCCAGACGAGCAGGGCCTGCAGCAGGTCCTGCAGCTGCTCAAAGACTCACAGTCGCCC AACACAGCCACTCAGCGCATCGTGCAGGATAAACTCAAACAACTCAATCAGTTTCCTGACTTCAACAAC TACCTGATTTTCGTCCTGACCAGACTCAAGTCAGAAGATGAGCCAACGCGCTCTCTCAGTGGCCTCATC CTCAAGAACAACGTGAAGGCACACTATCAGAGCTTCCCACCCCCTGTGGCAGACTTCATCAAACAGGAG TGTCTCAACAACATTGGCGATGCCTCCTCGCTCATCCGAGCCACCATTGGCATTCTCATCACCACCATC GCTTCCAAGGGTGAGCTGCAGATGTGGCCCGAGCTGCTGCCCCAGCTCTGCAACCTGCTTAACTCGGAG GATTACAACACTTGTGAGGGAGCCTTTGGAGCCCTGCAGAAGATCTGTGAAGACTCATCAGAGCTTCTG GACAGTGACGCCCTCAACAGGCCCCTCAACATCATGATCCCCAAGTTCCTGCAGTTCTTCAAGCACTGC AGTCCCAAGATCCGGTCCCACGCCATCGCCTGCGTGAACCAGTTCATCATGGACCGGGCCCAGGCGCTG ATGGACAATATTGACACCTTCATCGAGCACCTATTTGCCCTGGCTGTGGATGATGACCCCGAGGTGCGG AAGAATGTGTGCCGTGCCCTGGTGATGCTTCTGGAAGTGCGGATTGACAGGCTCATCCCCCACATGCAC AGCATCATCCAGTACATGCTGCAGAGGACCCAGGACCATGATGAGAACGTTGCCCTTGAGGCCTGTGAG TTCTGGCTGACGCTGGCCGAGCAGCCCATCTGCAAGGAAGTCCTGGCCTCCCATCTGGTCCAGTTGATC CCCATCTTGGTGAATGGGATGAAGTACTCGGAAATTGACATCATCCTGCTCAAGGGGGATGTGGAGGAG GATGAGGCTGTCCCCGACAGTGAGCAGGACATCAAGCCACGCTTCCACAAGTCACGCACGGTCACACTG CCCCACGAGGCTGAGCGGCCTGATGGCTCCGAGGACGCGGAGGATGACGATGATGATGATGCTCTGTCC GACTGGAATTTGAGGAAGTGCTCAGCGGCTGCACTGGACGTCCTCGCCAATGTCTTCCGGGAGGAACTG CTGCCCCACCTACTCCCACTACTCAAAGGCCTCCTCTTCCACCCCGAGTGGGTGGTCAAGGAGTCGGGC ATCCTGGTGCTGGGCGCCATTGCTGAGGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATC CCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGC CGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTC AAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAA GAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAA TACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCAC CTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGAC GAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTC CTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATG ATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACA TTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGAC CTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAAC CTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATG GGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAAC ACACCCAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATC GGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGC ACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATC GGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGC CCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGAT AACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTC TAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001136196 |
| Insert Size | 2694 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001136196.1 |
| RefSeq Size | 4949 bp |
| RefSeq ORF | 2694 bp |
| Locus ID | 30000 |
| UniProt ID | O14787 |
| MW | 101.4 kDa |
| Gene Summary | Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226797 | TNPO2 (Myc-DDK-tagged)-Human transportin 2 (TNPO2), transcript variant 1 |
CNY 6568.00 |
|
| RC226797L1 | Lenti ORF clone of Human transportin 2 (TNPO2), transcript variant 1, Myc-DDK-tagged |
CNY 8968.00 |
|
| RC226797L2 | Lenti ORF clone of Human transportin 2 (TNPO2), transcript variant 1, mGFP tagged |
CNY 9030.00 |
|
| RC226797L3 | Lenti ORF clone of Human transportin 2 (TNPO2), transcript variant 1, Myc-DDK-tagged |
CNY 9030.00 |
|
| RC226797L4 | Lenti ORF clone of Human transportin 2 (TNPO2), transcript variant 1, mGFP tagged |
CNY 9030.00 |
|
| RG226797 | TNPO2 (tGFP-tagged) - Human transportin 2 (TNPO2), transcript variant 1 |
CNY 7890.00 |
