KLHL2 (NM_001161521) Human Untagged Clone
CAT＃: SC327117
KLHL2 (untagged)-Human kelch-like 2 Mayven (Drosophila) (KLHL2) transcript variant 2
CNY 9690.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABP-KELCH; MAV; MAYVEN |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC327117 representing NM_001161521.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGTATGGTTGGAAGCACGGCCCCAGATTCTCTTTGTATGCACAAAGCAGGGTCATCAGAAGCCTCTC GATTCAAAAGATGATAATACCGAAAAACACTGCCCAGTGACAGTGAATCCTTGGCATATGAAGAAAGCT TTCAAAGTCATGAACGAATTAAGAAGTCAAAATTTGCTGTGCGATGTCACAATTGTGGCAGAAGACATG GAAATTTCTGCTCATAGAGTGGTGCTGGCCGCCTGTAGTCCTTATTTTCATGCCATGTTTACAGGTGAG ATGAGTGAGAGCCGAGCAAAGAGAGTTAGAATAAAAGAGGTAGATGGCTGGACCCTGAGGATGCTAATT GATTATGTTTACACTGCAGAAATTCAGGTTACAGAAGAAAATGTACAGGTACTTCTCCCAGCAGCTGGT CTCTTACAGTTACAGGATGTGAAGAAGACTTGTTGTGAATTTTTGGAATCCCAGCTTCACCCTGTCAAC TGCTTAGGAATCCGGGCTTTTGCTGATATGCATGCATGTACCGACCTTCTGAACAAGGCCAACACCTAT GCAGAGCAACATTTTGCAGATGTTGTACTTAGTGAAGAATTTCTCAATCTTGGCATCGAACAAGTGTGC AGCTTAATCTCAAGTGACAAACTTACCATTTCTTCAGAAGAGAAGGTATTTGAAGCAGTAATAGCATGG GTGAACCATGACAAGGATGTGAGGCAAGAGTTTATGGCCCGACTGATGGAACATGTACGGTTACCTTTG CTTCCTCGGGAATATTTAGTTCAGAGGGTTGAAGAGGAAGCATTGGTCAAGAATAGCAGTGCTTGCAAA GATTACCTCATTGAAGCAATGAAGTACCATTTGCTGCCAACAGAGCAGCGTATATTAATGAAGAGTGTC CGGACCCGGCTGAGGACACCCATGAACCTTCCCAAATTGATGGTGGTGGTTGGGGGCCAAGCACCAAAG GCTATCCGGAGTGTGGAATGCTATGACTTTAAAGAAGAAAGGTGGCACCAAGTAGCAGAGTTGCCTTCC AGGAGGTGCAGGGCAGGCATGGTCTACATGGCTGGACTTGTTTTTGCTGTTGGTGGCTTTAATGGCTCA TTAAGAGTTCGCACTGTAGATTCCTACGACCCTGTGAAGGACCAGTGGACCAGCGTTGCTAACATGAGA GACCGGAGAAGCACTTTGGGAGCTGCTGTGTTAAATGGATTATTATACGCTGTGGGAGGCTTTGATGGG AGTACAGGTTTGTCATCTGTGGAAGCATACAACATAAAGTCTAATGAGTGGTTTCATGTAGCTCCCATG AATACAAGGAGGAGCAGTGTTGGTGTGGGTGTTGTTGGAGGTTTGCTCTATGCTGTAGGAGGTTATGAT GGAGCATCACGTCAGTGTCTTAGCACAGTAGAATGCTATAATGCTACAACAAATGAGTGGACCTATATA GCAGAAATGAGCACCAGGCGGAGTGGAGCAGGTGTTGGTGTGTTAAACAATTTATTGTATGCTGTAGGA GGTCATGATGGCCCTTTAGTACGAAAAAGTGTTGAAGTATATGATCCCACCACTAACGCATGGAGACAG GTTGCAGATATGAACATGTGCAGAAGAAATGCAGGAGTTTGTGCAGTTAATGGTCTGTTATATGTTGTT GGAGGGGATGATGGTTCCTGTAACTTGGCGTCAGTAGAATATTATAACCCAACAACCGATAAATGGACA GTTGTGTCATCGTGTATGAGCACAGGGAGAAGTTATGCAGGGGTCACAGTTATTGATAAACCATTATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001161521 |
| Insert Size | 1794 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001161521.1 |
| RefSeq Size | 3014 bp |
| RefSeq ORF | 1794 bp |
| Locus ID | 11275 |
| UniProt ID | O95198 |
| MW | 66.6 kDa |
| Gene Summary | Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228482 | KLHL2 (Myc-DDK-tagged)-Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 2 |
CNY 4448.00 |
|
| RC228482L3 | Lenti-ORF clone of KLHL2 (Myc-DDK-tagged)-Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 2 |
CNY 7130.00 |
|
| RC228482L4 | Lenti-ORF clone of KLHL2 (mGFP-tagged)-Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 2 |
CNY 7130.00 |
|
| RG228482 | KLHL2 (tGFP-tagged) - Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 2 |
CNY 5700.00 |
