MICAL3 (NM_015241) Human Untagged Clone
CAT＃: SC328096
MICAL3 (untagged)-Human microtubule associated monoxygenase calponin and LIM domain containing 3 (MICAL3) transcript variant 1
CNY 38670.00
货期*
5周
规格
Product images
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MICAL-3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_015241, the custom clone sequence may differ by one or more nucleotides
ATGGAGGAGAGGAAGCATGAGACCATGAACCCAGCTCATGTCCTCTTTGACCGGTTTGTC CAGGCCACCACCTGCAAGGGAACCCTCAAGGCTTTCCAGGAGCTCTGTGACCACCTGGAA CTAAAGCCAAAGGACTACCGCTCCTTCTATCACAAGCTCAAGTCCAAGCTTAACTACTGG AAAGCCAAAGCCCTCTGGGCAAAATTGGACAAACGGGGCAGTCACAAAGACTACAAAAAG GGAAAAGCGTGCACTAACACCAAGTGTCTCATCATTGGGGCTGGCCCCTGTGGTCTCCGT ACAGCCATCGACTTATCCTTACTGGGGGCCAAGGTGGTTGTTATTGAGAAACGAGATGCC TTCTCCCGCAACAACGTCTTGCATCTCTGGCCATTCACCATACATGATCTACGAGGTCTG GGTGCCAAGAAGTTCTATGGCAAGTTCTGTGCTGGAGCCATCGACCATATCAGTATCCGT CAGCTCCAACTAATACTTTTGAAAGTAGCCTTGATCCTAGGCATTGAAATCCACGTCAAT GTGGAATTCCAAGGACTTATACAGCCTCCTGAGGACCAAGAGAATGAACGGATAGGCTGG CGGGCACTGGTGCACCCCAAGACTCATCCTGTGTCAGAGTATGAATTTGAAGTGATCATC GGTGGGGATGGTCGGAGGAACACCTTGGAAGGGTTTCGTCGGAAAGAATTCCGTGGCAAA CTGGCCATCGCCATCACGGCAAATTTTATCAACCGAAATACAACAGCAGAAGCTAAAGTG GAAGAGATCAGTGGTGTGGCTTTTATATTCAACCAAAAATTTTTCCAGGAACTGAGGGAA GCCACAGGTATTGACTTGGAGAACATCGTTTACTACAAAGATGACACACACTATTTCGTT ATGACAGCCAAAAAGCAGAGTTTGCTGGACAAAGGAGTGATACTACATGACTACGCCGAC ACAGAGCTCCTGCTTTCCCGAGAAAACGTGGACCAGGAGGCTCTGCTCAGCTATGCCAGG GAGGCGGCAGACTTCTCTACCCAGCAGCAGCTGCCGTCTCTGGATTTTGCCATCAATCAC TATGGGCAGCCCGATGTGGCCATGTTTGACTTCACTTGTATGTATGCCTCCGAGAACGCC GCCTTGGTGCGGGAGCAGAACGGACACCAGTTACTAGTGGCTCTGGTCGGGGACAGCCTC CTAGAGCCTTTCTGGCCAATGGGAACAGGAATAGCCCGGGGCTTTCTAGCTGCTATGGAC TCTGCCTGGATGGTCCGAAGTTGGTCTCTAGGAACGAGCCCTTTGGAAGTGCTGGCAGAG AGGGAAAGTATTTACAGGTTGCTGCCTCAGACCACCCCTGAGAATGTGAGTAAGAACTTC AGCCAGTACAGTATCGACCCTGTCACTCGGTATCCCAATATCAACGTCAACTTCCTCCGG CCAAGCCAGGTGCGCCATTTATATGATACTGGCGAAACAAAAGATATTCACCTGGAAATG GAGAGCCTGGTGAATTCCCGAACCACCCCCAAATTGACTCGCAATGAGTCTGTAGCTCGT TCAAGCAAACTGCTGGGTTGGTGCCAGAGGCAGACAGATGGCTATGCAGGGGTAAACGTG ACAGATCTCACCATGTCCTGGAAAAGTGGCTTGGCCCTTTGTGCAATTATCCATAGATAC CGCCCTGACCTGATAGATTTTGATTCTTTGGATGAGCAAAATGTGGAGAAGAATAACCAA CTGGCCTTTGACATTGCTGAGAAGGAATTGGGCATTTCTCCCATCATGACAGGCAAAGAA ATGGCCTCCGTGGGGGAGCCTGATAAGCTGTCCATGGTGATGTACCTGACTCAGTTCTAC GAGATGTTTAAGGACTCCCTCCCCTCTAGCGACACCTTGGACCTAAATGCCGAGGAGAAA GCAGTCCTGATAGCCAGCACCAGATCCCCTATCTCCTTCCTAAGCAAACTTGGCCAGACC ATCTCTCGGAAGCGTTCTCCCAAGGATAAAAAGGAAAAGGACTTGGATGGTGCTGGGAAG AGGAGAAAGACCAGTCAATCAGAGGAGGAGGAAGCTCCTCGGGGCCACAGAGGAGAAAGA CCGACCCTGGTGAGCACTCTGACAGACAGGAGGATGGACGTTGCCGTTGGGAACCAGAAC AAAGTGAAGTACATGGCGACCCAGCTGCTGGCCAAATTTGAAGAGAATGCGCCCGCACAG TCCATCGGCATACGGAGACAGGGCTCCATGAAGAAGGAGTTCCCGCAGAACCTGGGAGGC AGCGACACATGCTACTTCTGCCAGAAGCGGGTCTACGTGATGGAGAGGCTGAGTGCCGAG GGCAAGTTCTTCCACCGGAGCTGCTTCAAGTGCGAGTACTGCGCCACCACCCTGCGCCTC TCGGCCTACGCCTACGACATCGAGGATGGTAAATTCTACTGTAAGCCACACTACTGCTAT CGACTCTCTGGCTACGCACAAAGGAAGAGACCGGCAGTGGCTCCCCTGTCTGGAAAGGAG GCCAAAGGACCCCTGCAGGATGGCGCCACCACAGATGCAAACGGACGGGCCAACGCCGTG GCCAGCTCCACTGAGAGAACCCCAGGTTCAGGCGTGAACGGCCTGGAGGAGCCCAGCATC GCCAAGCGACTGAGGGGCACCCCAGAGCGGATCGAGCTGGAGAACTACCGCCTGTCCCTG AGGCAGGCTGAGGCACTGCAGGAGGTACCGGAGGAGACTCAGGCCGAGCACAACCTGAGC AGCGTGCTGGACACGGGCGCCGAGGAGGACGTCGCCAGCAGTAGTTCCGAGTCTGAGATG GAGGAGGAGGGAGAGGAGGAGGAGGAGGAGCCTCGCCTGCCCCCATCTGACCTGGGTGGT GTTCCGTGGAAGGAGGCCGTGCGGATCCATGCCCTTCTGAAAGGGAAAAGTGAAGAGGAG CTAGAGGCCTCAAAGAGCTTTGGGCCTGGGAATGAAGAGGAGGAGGAGGAGGAGGAAGAA TATGAAGAGGAGGAGGAGGAGGACTATGACGAGGAGGAGGAAGAGTCCAGTGAAGCCGGG AACCAGAGGCTCCAGCAGGTCATGCACGCGGCGGATCCTCTGGAGATCCAGGCTGACGTG CACTGGACTCATATCCGTGAGAGAGAGGAGGAAGAGAGGATGGCGCCGGCCTCTGAGTCC TCTGCTTCCGGAGCCCCATTGGATGAGAATGACCTAGAGGAAGATGTGGACTCAGAACCA GCCGAGATAGAAGGGGAGGCAGCAGAGGATGGGGACCCAGGGGACACTGGTGCTGAGCTG GATGATGATCAGCACTGGTCTGACAGCCCGTCGGATGCTGACAGAGAGCTGCGTTTGCCG TGCCCAGCTGAGGGGGAAGCAGAGCTGGAGCTGAGGGTGTCGGAAGATGAGGAGAAGCTG CCCGCCTCACCGAAGCACCAAGAGAGAGGTCCCTCCCAAGCCACCAGCCCCATCCGGTCT CCCCAGGAATCAGCTCTTCTGTTCATTCCAGTCCACAGCCCCTCAACAGAGGGGCCCCAA CTCCCACCTGTCCCTGCCGCCACCCAGGAGAAATCACCTGAGGAGCGCCTTTTCCCTGAG CCTTTGCTCCCCAAAGAGAAGCCCAAAGCTGATGCCCCCTCGGATCTGAAAGCTGTGCAC TCTCCCATCCGATCACAGCCAGTGACCCTGCCAGAAGCTAGGACTCCTGTCTCACCAGGG AGCCCGCAGCCCCAGCCACCCGTGGCGGCCTCCACGCCCCCACCCAGCCCACTCCCCATC TGCTCCCAGCCCCAGCCTTCCACCGAGGCCACTGTCCCATCCCCTACCCAGTCCCCCATA CGCTTCCAGCCTGCCCCGGCCAAAACATCCACCCCACTGGCCCCTCTCCCTGTCCAAAGC CAAAGTGACACCAAGGACAGACTGGGCAGCCCCCTTGCTGTGGATGAGGCCCTCAGACGG AGCGACCTGGTGGAGGAGTTCTGGATGAAGAGTGCGGAGATCCGCCGCAGCCTCGGGCTC ACACCTGTGGACCGCAGCAAGGGGCCCGAGCCCAGCTTCCCCACGCCTGCCTTCAGGCCA GTGTCCCTCAAATCCTATTCCGTTGAAAAGTCCCCCCAGGATGAGGGACTCCACCTTCTC AAGCCTCTGTCCATCCCCAAAAGGCTGGGCCTGCCAAAGCCGGAAGGCGAGCCGTTGTCC CTGCCAACCCCCCGGTCCCCGTCCGACAGAGAGCTACGCAGCGCCCAGGAGGAGCGCAGG GAGCTGTCCAGCAGCTCTGGCCTGGGCCTGCACGGGAGCTCCTCCAACATGAAGACACTG GGCAGCCAGAGCTTCAACACCTCGGACTCCGCCATGCTCACGCCCCCCTCCAGCCCGCCC CCACCGCCACCCCCGGGCGAGGAGCCCGCCACCTTGCGGAGGAAGCTCAGGGAGGCCGAG CCCAATGCCTCGGTGGTCCCGCCGCCCTTGCCCGCCACCTGGATGCGGCCCCCCCGGGAG CCTGCTCAGCCCCCCAGAGAGGAGGTGCGGAAGTCGTTTGTGGAGAGCGTGGAGGAGATT CCCTTTGCTGATGATGTGGAGGACACCTATGACGACAAGACTGAGGACTCAAGCCTGCAG GAGAAATTCTTCACGCCCCCGTCCTGCTGGCCGCGCCCCGAGAAGCCTCGCCACCCGCCC CTGGCCAAGGAGAACGGGAGGCTGCCTGCTCTGGAGGGGACGCTGCAGCCACAGAAGAGG GGGCTGCCCTTGGTGTCCGCGGAAGCCAAGGAGTTGGCCGAGGAGCGCATGCGAGCCAGG GAGAAGTCCGTGAAGAGCCAGGCGCTGCGGGACGCCATGGCCAGGCAGCTGAGCAGGATG CAGCAGATGGAGCTGGCCTCAGGCGCCCCCAGGCCCCGCAAGGCGTCCTCAGCACCCTCC CAGGGCAAGGAGCGCCGGCCTGACTCCCCCACACGCCCCACTCTCAGGGGCTCCGAGGAG CCCACCCTGAAGCATGAAGCCACCAGCGAGGAGGTCCTCTCCCCGCCGTCGGACTCAGGG GGCCCAGATGGCTCTTTCACTTCATCCGAGGGCTCCAGTGGGAAGAGCAAGAAGAGGTCG TCACTCTTCTCCCCCCGCAGAAACAAGAAGGAGAAGAAGTCCAAAGGCGAGGGCCGGCCC CCGGAGAAGCCCAGCTCCAACCTCCTAGAAGAAGCCGCCGCCAAACCCAAGTCCCTGTGG AAGTCCGTCTTCTCCGGGTACAAGAAGGACAAGAAGAAGAAGGCCGACGACAAGTCCTGC CCCAGCACCCCCTCCAGCGGGGCCACGGTGGACTCTGGAAAGCACAGGGTGCTTCCCGTC GTAAGGGCAGAGCTGCAGCTCCGGCGCCAGCTGAGCTTCTCCGAGGACTCAGACCTCTCC AGCGACGATGTCCTTGAGAAGTCCTCACAGAAGTCCCGGCGAGAGCCAAGAACCTACACG GAGGAGGAACTGAATGCCAAGCTGACCCGGCGTGTGCAAAAGGCAGCTCGGAGACAGGCC AAGCAGGAGGAGCTTAAGCGGCTGCATCGAGCCCAGATCATCCAGCGGCAGCTGCAGCAG GTGGAGGAGAGGCAGCGGCGGCTGGAGGAAAGGGGCGTGGCTGTGGAGAAGGCGCTCCGG GGCGAAGCAGGCATGGGCAAGAAGGACGACCCCAAGCTGATGCAGGAGTGGTTCAAGCTA GTGCAGGAGAAGAACGCCATGGTGCGCTACGAGTCGGAGCTGATGATCTTTGCCCGGGAG CTGGAGCTGGAAGACCGGCAGAGTCGACTGCAGCAGGAGCTCCGGGAACGCATGGCAGTG GAAGATCACCTTAAGACTGAGGAGGAGCTGTCAGAAGAGAAGCAGATTCTCAATGAGATG CTGGAGGTGGTGGAGCAGAGAGACTCACTGGTGGCGCTGCTGGAGGAGCAGCGGCTCCGG GAGAGAGAGGAGGACAAGGACCTGGAGGCTGCCATGCTGTCCAAGGGCTTCAGCCTTAAC TGGTCC |
| Restriction Sites | Please inquire |
| ACCN | NM_015241 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015241.2, NP_056056.2 |
| RefSeq Size | 9471 bp |
| RefSeq ORF | 6009 bp |
| Locus ID | 57553 |
| UniProt ID | Q7RTP6 |
| Gene Summary | Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Seems to act as Rab effector protein and plays a role in vesicle trafficking. Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this process and implicates RAB8A associated with exocytotic vesicles. Required for cytokinesis. Contributes to stabilization and/or maturation of the intercellular bridge independently of its monooxygenase activity. Promotes recruitment of Rab8 and ERC1 to the intercellular bridge, and together these proteins are proposed to function in timely abscission.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC229461 | MICAL3 (Myc-DDK-tagged)-Human microtubule associated monoxygenase, calponin and LIM domain containing 3 (MICAL3), transcript variant 1 |
CNY 18990.00 |
|
| RG229461 | MICAL3 (tGFP-tagged) - Human microtubule associated monoxygenase, calponin and LIM domain containing 3 (MICAL3), transcript variant 1 |
CNY 21424.00 |
|
| SC316581 | MICAL3 (untagged)-Human microtubule associated monoxygenase, calponin and LIM domain containing 3 (MICAL3), transcript variant 1 |
CNY 38670.00 |
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