CARKD (NAXD) (NM_001242881) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CARKD; LP3298; PEBEL2
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331910 representing NM_001242881. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGTCACACGCGCGGGGGCCGGAACTGCCGTCGCCGGCGCGGTCGTTGTCGCATTGCTCTCGGCCGCA CTCGCGCTGTACGGGCCGCCACTGGACGCAGTTTTAGAAAGAGCGTTTTCGCTACGTAAAGCACATTCG ATAAAGGATATGGAAAATACTTTGCAGCTGGTGAGAAATATCATACCTCCTCTGTCTTCCACAAAGCAC AAAGGGCAAGATGGAAGAATAGGCGTAGTTGGAGGCTGTCAGGAGTACACTGGAGCCCCATATTTTGCA GCAATCTCAGCTCTCAAAGTGGGCGCAGACTTGTCCCACGTGTTCTGTGCCAGTGCGGCCGCACCTGTG ATTAAGGCCTACAGCCCGGAGCTGATCGTCCACCCAGTTCTTGACAGCCCCAATGCTGTTCATGAGGTG GAGAAGTGGCTGCCCCGGCTGCATGCTCTTGTCGTAGGACCTGGCTTGGGTAGAGATGATGCGCTTCTC AGAAATGTCCAGGGCATTTTGGAAGTGTCAAAGGCCAGGGACATCCCTGTTGTCATCGACGCGGATGGC CTGTGGCTGGTCGCTCAGCAGCCGGCCCTCATCCATGGCTACCGGAAGGCTGTGCTCACTCCCAACCAC GTGGAGTTCAGCAGACTGTATGACGCTGTGCTCAGAGGCCCTATGGACAGCGATGACAGCCATGGATCT GTGCTAAGACTCAGCCAAGCCCTGGGCAACGTGACGGTGGTCCAGAAAGGAGAGCGCGACATCCTCTCC AACGGCCAGCAGGTGCTTGTGTGCAGCCAGGAAGGCAGCAGCCGCAGGTGTGGAGGGCAAGGGGACCTC CTGTCGGGCTCCCTGGGCGTCCTGGTACACTGGGCGCTCCTTGCTGGACCACAGAAAACAAATGGGTCC AGCCCTCTCCTGGTGGCCGCGTTTGGCGCCTGCTCTCTCACCAGGCAGTGCAACCACCAAGCCTTCCAG AAGCACGGTCGCTCCACCACCACCTCCGACATGATCGCCGAGGTGGGGGCCGCCTTCAGCAAGCTCTTT GAAACCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001242881
Insert Size	1044 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001242881.1
RefSeq Size	2620 bp
RefSeq ORF	1044 bp
Locus ID	55739
UniProt ID	Q8IW45
Protein Families	Transmembrane
MW	36.6 kDa
Gene Summary	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate splice site that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct and shorter C-terminus, compared to isoform a.

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