Igk (BC028540) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR202838L4V

LentiORF^®

Lenti ORF particles, MGC:41421 (GFP-tagged) - Mouse cDNA clone MGC:41421 IMAGE:3371732, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

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CNY 11115.00

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Cited in 180 publications.

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Specifications

Product Data
Product Name	Igk (BC028540) Mouse Tagged ORF Clone Lentiviral Particle
Vector	pLenti-C-mGFP-P2A-Puro
ACCN	BC028540
ORF Size	702 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(MR202838).
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	BC028540
RefSeq Size	943 bp
RefSeq ORF	704 bp
Locus ID	243469
Gene Summary	Summary:Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the kappa light chain locus from the C57BL/6J inbred mouse strain. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments in this cluster are incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Jul 2008]

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Citations (180)

The use of this cDNA Clones has been cited in the following citations:
High Levels of Hyaluronic Acid Synthase-2 Mediate NRF2-Driven Chemoresistance in Breast Cancer Cells ,null, Biomolecules & Therapeutics ,PubMed ID 35768333 [Igk]
A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells ,null, Experimental Hematology & Oncology ,PubMed ID 35831896 [Igk]
ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL-8/Notch signaling cascade ,null, International Journal of Molecular Medicine ,PubMed ID 35656893 [Igk]
MEX3A promotes the malignant progression of ovarian cancer by regulating intron retention in TIMELESS ,null, Cell Death & Disease ,PubMed ID 35715407 [Igk]
FOXK2 promotes ovarian cancer stemness by regulating the unfolded protein response pathway ,null, The Journal of Clinical Investigation ,PubMed ID 35349489 [Igk]
Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism ,null, Cell Death & Disease ,PubMed ID 35428778 [Igk]
The Autophagy Protein Pacer Positively Regulates the Therapeutic Potential of Mesenchymal Stem Cells in a Mouse Model of DSS-Induced Colitis ,null, Cells ,PubMed ID 35563809 [Igk]
Senecavirus a 3D Interacts with NLRP3 to Induce IL-1β Production by Activating NF-κB and Ion Channel Signals ,null, Microbiology Spectrum ,PubMed ID 35254168 [Igk]
The BCAT1 CXXC Motif Provides Protection against ROS in Acute Myeloid Leukaemia Cells ,null, Antioxidants ,PubMed ID 35453368 [Igk]
The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal, et al. The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal ,null, FASEB BioAdvances ,PubMed ID 35664831 [Igk]
Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α ,null, Science Advances ,PubMed ID 35179955 [Igk]
Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer ,null, Journal of Experimental & Clinical Cancer Research : CR ,PubMed ID 35039048 [Igk]
RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation ,null, Nature Communications ,PubMed ID 34887419 [Igk]
Peroxidasin Enhances Basal Phenotype and Inhibits Branching Morphogenesis in Breast Epithelial Progenitor Cell Line D492 ,null, Journal of Mammary Gland Biology and Neoplasia ,PubMed ID 34964086 [Igk]
FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1β Production ,null, Viruses ,PubMed ID 35062226 [Igk]
ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis ,null, Frontiers in Molecular Biosciences ,PubMed ID 34805267 [Igk]
TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models ,null, Cellular and Molecular Gastroenterology and Hepatology ,PubMed ID 34823063 [Igk]
THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer, THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer ,null, Advanced Science ,PubMed ID 34708581 [Igk]
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection ,null, Cell Reports ,PubMed ID 34731648 [Igk]
Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells ,null, Cell Metabolism ,PubMed ID 34358431 [Igk]
Integrative Network Analysis Revealed Genetic Impact of Pyruvate Kinase L/R on Hepatocyte Proliferation and Graft Survival after Liver Transplantation ,null, Oxidative Medicine and Cellular Longevity ,PubMed ID 34512869 [Igk]
Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropism and virulence ,null, Cell Reports ,PubMed ID 34551286 [Igk]
Cannabinoid Receptor Type 1 Regulates Drug Reward Behavior via Glutamate Decarboxylase 67 Transcription ,null, International Journal of Molecular Sciences ,PubMed ID 34638827 [Igk]
CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation ,null, Frontiers in Molecular Neuroscience ,PubMed ID 34421533 [Igk]
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy ,null, Immunity ,PubMed ID 34453881 [Igk]
Dipeptidyl peptidase 4 contributes to Alzheimer’s disease–like defects in a mouse model and is increased in sporadic Alzheimer’s disease brains ,null, The Journal of Biological Chemistry ,PubMed ID 34265307 [Igk]
Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism ,null, Cell Death Discovery ,PubMed ID 34290233 [Igk]
Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1 ,null, Frontiers in Immunology ,PubMed ID 34305888 [Igk]
Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype ,null, Genetics in Medicine ,PubMed ID 34145395 [Igk]
METTL3 increases cisplatin chemosensitivity of cervical cancer cells via downregulation of the activity of RAGE ,null, Molecular Therapy Oncolytics ,PubMed ID 34514103 [Igk]
89Zr-Labeled Anti-PD-L1 Antibody PET Monitors Gemcitabine Therapy-Induced Modulation of Tumor PD-L1 Expression ,null, Journal of Nuclear Medicine ,PubMed ID 32917780 [Igk]
Regulation of Synovial Inflammation and Tissue Destruction by Guanylate Binding Protein 5 in Synovial Fibroblasts From Patients With Rheumatoid Arthritis and Rats With Adjuvant-Induced Arthritis ,null, Arthritis & rheumatology (Hoboken, N.J.) ,PubMed ID 33615742 [Igk]
Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis ,null, Redox Biology ,PubMed ID 33946018 [Igk]
Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma ,null, Molecular Oncology ,PubMed ID 33605536 [Igk]
MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts ,null, Aging (Albany NY) ,PubMed ID 33621951 [Igk]
Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation ,null, Nature Communications ,PubMed ID 33568645 [Igk]
The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma ,null, Scientific Reports ,PubMed ID 33574425 [Igk]
Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase ,null, Oncogenesis ,PubMed ID 33637682 [Igk]
Lactate Dehydrogenase A as a Potential New Biomarker for Thyroid Cancer ,null, Endocrinology and Metabolism ,PubMed ID 33677931 [Igk]
Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D ,null, Frontiers in Neuroscience ,PubMed ID 33679286 [Igk]
Laminin N-terminus α31 protein distribution in adult human tissues ,null, PLoS ONE ,PubMed ID 33264294 [Igk]
Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17 ,null, Cell reports ,PubMed ID 33207199 [Igk]
Identification of CD137-Expressing B Cells in Multiple Sclerosis Which Secrete IL-6 Upon Engagement by CD137 Ligand ,null, Frontiers in Immunology ,PubMed ID 33240262 [Igk]
VRK1 Phosphorylates Tip60/KAT5 and Is Required for H4K16 Acetylation in Response to DNA Damage ,null, Cancers ,PubMed ID 33076429 [Igk]
Protein Tyrosine Phosphatase Receptor S Acts as a Metastatic Suppressor in Malignant Peripheral Nerve Sheath Tumor via Profilin 1-Induced Epithelial-Mesenchymal Transition ,null, Frontiers in Cell and Developmental Biology ,PubMed ID 33163494 [Igk]
Klotho overexpression improves amyloid‐β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease ,null, Aging Cell ,PubMed ID 32964663 [Igk]
Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike ,null, Cell Reports. Medicine ,PubMed ID 33015650 [Igk]
Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells ,null, Cells ,PubMed ID 32756469 [Igk]
Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5 ,null, mAbs ,PubMed ID 32835602 [Igk]
Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma. ,null, Oncogene ,PubMed ID 32855525 [Igk]
Human CLPB forms ATP-dependent complexes in the mitochondrial intermembrane space. ,null, The international journal of biochemistry cell biology ,PubMed ID 32866687 [Igk]
Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes ,null, Science Advances ,PubMed ID 32875100 [Igk]
Pazopanib and Trametinib as a Synergistic Strategy against Osteosarcoma: Preclinical Activity and Molecular Insights ,null, Cancers ,PubMed ID 32531992 [Igk]
Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPAR α ,null, JCI Insight ,PubMed ID 32315292 [Igk]
Differential Glucocorticoid-Dependent Regulation and Function of the ERRFI1 Gene in Triple-Negative Breast Cancer ,null, Endocrinology ,PubMed ID 32432675 [Igk]
Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing ,null, PLoS ONE ,PubMed ID 32437477 [Igk]
Effect of AGER on the biological behavior of non-small cell lung cancer H1299 cells ,null, Molecular Medicine Reports ,PubMed ID 32468030 [Igk]
PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway. ,null, Carcinogenesis ,PubMed ID 31095674 [Igk]
GPR56/ADGRG1 is associated with response to antidepressant treatment ,null, Nature Communications ,PubMed ID 32242018 [Igk]
Glucose-Stimulated Insulin Secretion Fundamentally Requires H2O2 Signaling by NADPH Oxidase 4 ,null, Diabetes ,PubMed ID 32245800 [Igk]
Long Non-Coding RNA LEF1-AS1 Promotes Migration, Invasion and Metastasis of Colon Cancer Cells Through miR-30-5p/SOX9 Axis ,null, OncoTargets and therapy ,PubMed ID 32308428 [Igk]
Downregulation of RAGE Inhibits Cell Proliferation and Induces Apoptosis via Regulation of PI3K/AKT Pathway in Cervical Squamous Cell Carcinoma ,null, OncoTargets and therapy ,PubMed ID 32256089 [Igk]
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity. ,null, Cell reports ,PubMed ID 32049014 [Igk]
AGO2 mediates MYC mRNA stability in hepatocellular carcinoma ,null, Molecular cancer research : MCR ,PubMed ID 31941754 [Igk]
CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility ,null, eLife ,PubMed ID 31971513 [Igk]
ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output ,null, Cancers ,PubMed ID 31817719 [Igk]
Prohibitin levels regulate OMA1 activity and turnover in neurons ,null, Cell Death and Differentiation ,PubMed ID 31819158 [Igk]
B7-H3 Induces Ovarian Cancer Drugs Resistance Through An PI3K/AKT/BCL-2 Signaling Pathway ,null, Cancer Management and Research ,PubMed ID 31819652 [Igk]
Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer. ,null, Cancer letters ,PubMed ID 31765735 [Igk]
Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake ,null, Communications Biology ,PubMed ID 31646189 [Igk]
BC200 overexpression contributes to luminal and triple negative breast cancer pathogenesis ,null, BMC Cancer ,PubMed ID 31646972 [Igk]
Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer ,null, Molecular Therapy Oncolytics ,PubMed ID 31720371 [Igk]
Activation of TFEB ameliorates dedifferentiation of arterial smooth muscle cells and neointima formation in mice with high-fat diet ,null, Cell Death & Disease ,PubMed ID 31515484 [Igk]
Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F ,null, Oncogene ,PubMed ID 31527668 [Igk]
NPC1 enables cholesterol mobilization during long‐term potentiation that can be restored in Niemann–Pick disease type C by CYP46A1 activation ,null, EMBO Reports ,PubMed ID 31535451 [Igk]
Prolactin promotes fibrosis and pancreatic cancer progression ,null, Cancer research ,PubMed ID 31395607 [Igk]
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer disease risk ,null, Science translational medicine ,PubMed ID 31413141 [Igk]
mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn’s Disease ,null, Cells ,PubMed ID 31426584 [Igk]
HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer ,null, Oncogenesis ,PubMed ID 31431614 [Igk]
STING signaling in melanoma cells shapes antigenicity and can promote antitumor T-cell activity ,null, Cancer immunology research ,PubMed ID 31462408 [Igk]
Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection ,null, PLoS Pathogens ,PubMed ID 31356650 [Igk]
The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases ,null, Oncogene ,PubMed ID 31253868 [Igk]
Mitochondrial protein 18 is a positive apoptotic regulator in cardiomyocytes under oxidative stress. ,null, Clinical science (London, England : 1979) ,PubMed ID 31015359 [Igk]
AIF-regulated oxidative phosphorylation supports lung cancer development ,null, Cell Research ,PubMed ID 31133695 [Igk]
A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer ,null, Cell Death & Disease ,PubMed ID 31138788 [Igk]
The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair ,null, Nucleic Acids Research ,PubMed ID 30812030 [Igk]
YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells ,null, Nature Communications ,PubMed ID 30931946 [Igk]
The mitochondrial metabolic function of DJ-1 is modulated by 14-3-3β ,null, The FASEB Journal ,PubMed ID 31034784 [Igk]
Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ ,null, Scientific Reports ,PubMed ID 31040372 [Igk]
Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain ,null, Pain ,PubMed ID 30422869 [Igk]
Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype ,null, Cell Death & Disease ,PubMed ID 30741928 [Igk]
RNA binding antagonizes neurotoxic phase transitions of TDP-43. ,null, Neuron ,PubMed ID 30826182 [Igk]
The role of Slit2 as a tumor suppressor in thyroid cancer. ,null, Molecular and cellular endocrinology ,PubMed ID 30648543 [Igk]
Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity ,null, Journal of Ovarian Research ,PubMed ID 30651135 [Igk]
Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma ,null, Oncogene ,PubMed ID 30651601 [Igk]
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment ,null, Cell stem cell ,PubMed ID 30686763 [Igk]
Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells ,null, Journal of Experimental & Clinical Cancer Research : CR ,PubMed ID 30541574 [Igk]
Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis, et al. Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis ,null, Glia ,PubMed ID 30578556 [Igk]
Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 30352848 [Igk]
Melatonin protects chronic kidney disease mesenchymal stem cells against senescence via PrPC -dependent enhancement of the mitochondrial function. ,null, Journal of pineal research ,PubMed ID 30372554 [Igk]
TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw ,null, Nature Communications ,PubMed ID 30385747 [Igk]
Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene ,null, Cell Death & Disease ,PubMed ID 30451833 [Igk]
New Insights into the Runt Domain of RUNX2 in Melanoma Cell Proliferation and Migration ,null, Cells ,PubMed ID 30463392 [Igk]
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis ,null, Nature Communications ,PubMed ID 30464173 [Igk]
Immune Effector Functions of Human IgG2 Antibodies against EGFR. ,null, Molecular cancer therapeutics ,PubMed ID 30282813 [Igk]
Fos-like antigen 2 (FOSL2) promotes metastasis in colon cancer. ,null, Experimental cell research ,PubMed ID 30114390 [Igk]
A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2 ,null, Journal of Biological Engineering ,PubMed ID 30127847 [Igk]
Multi-Kinase Inhibitor with Anti-p38γ Activity in Cutaneous T-Cell Lymphoma ,null, The Journal of investigative dermatology ,PubMed ID 29758280 [Igk]
Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention ,null, The Journal of Neuroscience ,PubMed ID 29967007 [Igk]
Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma ,null, Oncogene ,PubMed ID 29980786 [Igk]
Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 30012602 [Igk]
Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis ,null, Frontiers in Immunology ,PubMed ID 30072988 [Igk]
Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma ,null, Cellular and Molecular Gastroenterology and Hepatology ,PubMed ID 30258965 [Igk]
Upregulation of KIF26B, Cell Migration and Proliferation of Human Ovarian Cancer Cell Lines In Vitro, and Patient Outcomes from Human Bioinformatic Analysis ,null, Medical Science Monitor : International Medical Journal of Experimental and Clinical Research ,PubMed ID 29880787 [Igk]
UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation ,null, BMC Biotechnology ,PubMed ID 29764417 [Igk]
cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells ,null, Cell Death and Differentiation ,PubMed ID 29674627 [Igk]
Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival ,null, Nature Communications ,PubMed ID 29674746 [Igk]
The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages ,null, Frontiers in Immunology ,PubMed ID 29666621 [Igk]
Interleukin-30/IL27p28 Shapes Prostate Cancer Stem-like Cell Behavior and Is Critical for Tumor Onset and Metastasization. ,null, Cancer research ,PubMed ID 29487200 [Igk]
AGER promotes proliferation and migration in cervical cancer ,null, Bioscience Reports ,PubMed ID 29298878 [Igk]
Innate Sensing of Influenza A Virus Hemagglutinin Glycoproteins by the Host Endoplasmic Reticulum (ER) Stress Pathway Triggers a Potent Antiviral Response via ER-Associated Protein Degradation ,null, Journal of Virology ,PubMed ID 29046440 [Igk]
Mesoderm specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy ,null, Journal of cellular biochemistry ,PubMed ID 29058774 [Igk]
Role of Dopamine Receptors in the Anticancer Activity of ONC201 ,null, Neoplasia (New York, N.Y.) ,PubMed ID 29216597 [Igk]
Empowering human cardiac progenitor cells by P2Y14 nucleotide receptor overexpression ,null, The Journal of Physiology ,PubMed ID 28980705 [Igk]
HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD ,null, Scientific Reports ,PubMed ID 29042644 [Igk]
Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence ,null, Cancer research ,PubMed ID 29055014 [Igk]
CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression ,null, Oncotarget ,PubMed ID 29152125 [Igk]
E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion ,null, Oncotarget ,PubMed ID 29163761 [Igk]
p53 gain‐of‐function mutations increase Cdc7‐dependent replication initiation ,null, EMBO Reports ,PubMed ID 28887320 [Igk]
Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas ,null, International journal of cancer ,PubMed ID 28646488 [Igk]
Nrf2 deficiency exacerbates ochratoxin A-induced toxicity in vitro and in vivo. ,null, Toxicology ,PubMed ID 28710020 [Igk]
OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma ,null, Carcinogenesis ,PubMed ID 28911005 [Igk]
Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells ,null, Oncotarget ,PubMed ID 28418925 [Igk]
Mutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers ,null, Cell Death & Disease ,PubMed ID 28661474 [Igk]
PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism. ,null, Cell metabolism ,PubMed ID 28467929 [Igk]
Fibulin-3 promotes muscle-invasive bladder cancer. ,null, Oncogene ,PubMed ID 28504717 [Igk]
Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart ,null, The Journal of Biological Chemistry ,PubMed ID 28154187 [Igk]
Depletion of Gangliosides Enhances Articular Cartilage Repair in Mice ,null, Scientific Reports ,PubMed ID 28252046 [Igk]
Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells. ,null, Nitric oxide : biology and chemistry ,PubMed ID 28257996 [Igk]
FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination ,null, Human Molecular Genetics ,PubMed ID 28025327 [Igk]
Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division ,null, Scientific Reports ,PubMed ID 28059125 [Igk]
Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain ,null, eLife ,PubMed ID 28079521 [Igk]
Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation ,null, PLoS ONE ,PubMed ID 27907090 [Igk]
Non-invasive imaging using reporter genes altering cellular water permeability ,null, Nature Communications ,PubMed ID 28008959 [Igk]
RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. ,null, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology ,PubMed ID 27606466 [Igk]
Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells. ,null, Free radical biology medicine ,PubMed ID 27693380 [Igk]
Enzyme overexpression – an exercise toward understanding regulation of heparan sulfate biosynthesis ,null, Scientific Reports ,PubMed ID 27511124 [Igk]
Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion ,null, Diabetes ,PubMed ID 26993066 [Igk]
Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors ,null, Acta neuropathologica ,PubMed ID 26920151 [Igk]
Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors ,null, EBioMedicine ,PubMed ID 27211548 [Igk]
Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression ,null, Nature Communications ,PubMed ID 26671628 [Igk]
Bidirectional Signaling of Neuregulin-2 Mediates Formation of GABAergic Synapses and Maturation of Glutamatergic Synapses in Newborn Granule Cells of Postnatal Hippocampus ,null, The Journal of Neuroscience ,PubMed ID 26674872 [Igk]
Overexpression of the Monocyte Chemokine CCL2 in Dorsal Root Ganglion Neurons Causes a Conditioning-Like Increase in Neurite Outgrowth and Does So via a STAT3 Dependent Mechanism ,null, Experimental neurology ,PubMed ID 26431741 [Igk]
H-rev107 Regulates Cytochrome P450 Reductase Activity and Increases Lipid Accumulation ,null, PLoS ONE ,PubMed ID 26381418 [Igk]
Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice ,null, Cellular and molecular gastroenterology and hepatology ,PubMed ID 26740970 [Igk]
Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 26080426 [Igk]
Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation ,null, Scientific Reports ,PubMed ID 26108359 [Igk]
mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity ,null, Endocrine-Related Cancer ,PubMed ID 26113609 [Igk]
Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism ,null, Oncoimmunology ,PubMed ID 26942078 [Igk]
A Conserved Function in Phosphatidylinositol Metabolism for Mammalian Vps13 Family Proteins ,null, PLoS ONE ,PubMed ID 25915401 [Igk]
Receptor Tyrosine Kinase EphA5 Is a Functional Molecular Target in Human Lung Cancer * ,null, The Journal of Biological Chemistry ,PubMed ID 25623065 [Igk]
Targeting the MLL complex in castration resistant prostate cancer ,null, Nature medicine ,PubMed ID 25822367 [Igk]
Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines ,null, Stem Cell Research & Therapy ,PubMed ID 25559585 [Igk]
Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent. ,null, Biochemical and biophysical research communications ,PubMed ID 25173938 [Igk]
miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7 ,null, Cell Death & Disease ,PubMed ID 25077541 [Igk]
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer ,null, Nature communications ,PubMed ID 25078033 [Igk]
Numb Regulates Glioma Stem Cell Fate and Growth by Altering Epidermal Growth Factor Receptor and Skp1-Cullin-F-Box Ubiquitin Ligase Activity ,null, Stem cells (Dayton, Ohio) ,PubMed ID 22553175 [Igk]
Presenilins Regulate Neurotrypsin Gene Expression and Neurotrypsin-dependent Agrin Cleavage via Cyclic AMP Response Element-binding Protein (CREB) Modulation * ,null, The Journal of Biological Chemistry ,PubMed ID 24145027 [Igk]
The Overexpression of Scaffolding Protein NEDD9 Promotes Migration and Invasion in Cervical Cancer via Tyrosine Phosphorylated FAK and SRC ,null, PLoS ONE ,PubMed ID 24058594 [Igk]
The tumor suppressor CDKN3 controls mitosis ,null, The Journal of Cell Biology ,PubMed ID 23775190 [Igk]
FGFR4 Role in Epithelial-Mesenchymal Transition and Its Therapeutic Value in Colorectal Cancer ,null, PLoS ONE ,PubMed ID 23696849 [Igk]
P21 Activated Kinase-1 (Pak1) Promotes Prostate Tumor Growth and Microinvasion via Inhibition of Transforming Growth Factor ? Expression and Enhanced Matrix Metalloproteinase 9 Secretion * ,null, The Journal of Biological Chemistry ,PubMed ID 23258534 [Igk]
The Lifetime of UDP-galactose:Ceramide Galactosyltransferase Is Controlled by a Distinct Endoplasmic Reticulum-associated Degradation (ERAD) Regulated by Sigma-1 Receptor Chaperones * ,null, The Journal of Biological Chemistry ,PubMed ID 23105111 [Igk]
TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells ,null, Molecular cancer research : MCR ,PubMed ID 22952044 [Igk]
STING Mediates Neuronal Innate Immune Response Following Japanese Encephalitis Virus Infection ,null, Scientific Reports ,PubMed ID 22470840 [Igk]
Identification of Membrane-bound Variant of Metalloendopeptidase Neurolysin (EC 3.4.24.16) as the Non-angiotensin Type 1 (Non-AT1), Non-AT2 Angiotensin Binding Site * ,null, The Journal of Biological Chemistry ,PubMed ID 22039052 [Igk]
Membrane protein GARP is a receptor for latent TGF-β on the surface of activated human Treg ,null, European Journal of Immunology ,PubMed ID 19750484 [Igk]
Three Promoters Regulate Tissue- and Cell Type-specific Expression of Murine Interleukin-1 Receptor Type I ,null, The Journal of Biological Chemistry ,PubMed ID 19196714 [Igk]
At Least Ten Genes Define the Imprinted Dlk1-Dio3 Cluster on Mouse Chromosome 12qF1 ,null, PLoS ONE ,PubMed ID 19194500 [Igk]
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 11274398 [Igk]

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