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UMPS (NM_000373) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC201324L4V
- LentiORF®
-
Lenti ORF particles, UMPS (mGFP-tagged) - Human uridine monophosphate synthetase (UMPS), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | UMPS (NM_000373) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | OPRT |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_000373 |
| ORF Size | 1440 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201324).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000373.1 |
| RefSeq Size | 6738 bp |
| RefSeq ORF | 1443 bp |
| Locus ID | 7372 |
| Domains | Pribosyltran, OMPdecase |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism |
| MW | 52.2 kDa |
| Gene Summary | This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
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