C16orf57 (USB1) (NM_024598) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202591L3V
- LentiORF®
Lenti ORF particles, USB1 (Myc-DDK tagged) - Human chromosome 16 open reading frame 57 (C16orf57), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Product Name | C16orf57 (USB1) (NM_024598) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | C16orf57; hUsb1; HVSL1; Mpn1; PN |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_024598 |
ORF Size | 795 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202591).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024598.2 |
RefSeq Size | 2287 bp |
RefSeq ORF | 798 bp |
Locus ID | 79650 |
MW | 30.3 kDa |
Gene Summary | This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011] |
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