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SRC (NM_005417) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC208622L3V
- LentiORF®
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Lenti ORF particles, SRC (Myc-DDK tagged) - Human v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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| Product Data | |
| Product Name | SRC (NM_005417) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ASV; c-SRC; p60-Src; SRC1; THC6 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_005417 |
| ORF Size | 1608 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208622).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_005417.3 |
| RefSeq Size | 4145 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 6714 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Stem cell relevant signaling - JAK/STAT signaling pathway |
| Protein Pathways | Adherens junction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Focal adhesion, Gap junction, GnRH signaling pathway, Tight junction, VEGF signaling pathway |
| MW | 59.7 kDa |
| Gene Summary | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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